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Christopher A. Walsh

Researcher at Howard Hughes Medical Institute

Publications -  470
Citations -  62520

Christopher A. Walsh is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Cerebral cortex & Microcephaly. The author has an hindex of 123, co-authored 455 publications receiving 55874 citations. Previous affiliations of Christopher A. Walsh include University of Liverpool & Newcastle University.

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PaSD-qc: Quality control for single cell whole-genome sequencing data using power spectral density estimation

TL;DR: A statistical method that uses a modified power spectral density to assess amplification uniformity, amplicon size distribution, autocovariance, and inter-sample consistency as well as identifies aberrantly amplified chromosomes is presented.
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TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system

Shyam K. Akula, +232 more
TL;DR: In this article , the authors identified TMEM161B, a gene with previously unknown function that is part of no known protein superfamily, and showed that disrupting Tmem161b in utero is sufficient to lead to gyration abnormalities in a ferret model.

The specificity of interactions between the cortex and the thalamus - Discussion

TL;DR: It is presented evidence that activity conveyed by thalamic afferents is required for the elaboration of the columnar specificity of cortical circuits and that the establishment of the development of layer-specific patterns of afferent and efferent cortical connections does not depend upon neuronal activity.