C
Claudia Conrad
Researcher at Charité
Publications - 16
Citations - 1495
Claudia Conrad is an academic researcher from Charité. The author has contributed to research in topics: Immune system & Streptococcus pneumoniae. The author has an hindex of 8, co-authored 13 publications receiving 835 citations. Previous affiliations of Claudia Conrad include Humboldt University of Berlin.
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Journal ArticleDOI
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Jonas Schulte-Schrepping,Nico Reusch,Daniela Paclik,Kevin Baßler,Stephan Schlickeiser,Bowen Zhang,Benjamin Krämer,Tobias Krammer,Sophia Brumhard,Lorenzo Bonaguro,Elena De Domenico,Daniel Wendisch,Martin Grasshoff,Theodore S. Kapellos,Michael Beckstette,Tal Pecht,Adem Saglam,Oliver Dietrich,Henrik E. Mei,Axel Schulz,Claudia Conrad,Désirée Kunkel,Ehsan Vafadarnejad,Cheng-Jian Xu,Cheng-Jian Xu,Arik Horne,Miriam Herbert,Anna Drews,Charlotte Thibeault,Moritz Pfeiffer,Stefan Hippenstiel,Andreas C. Hocke,Holger Müller-Redetzky,Katrin-Moira Heim,Felix Machleidt,Alexander Uhrig,Laure Bosquillon de Jarcy,Linda Jürgens,Miriam Stegemann,Christoph R. Glösenkamp,Hans-Dieter Volk,Christine Goffinet,Markus Landthaler,Emanuel Wyler,Philipp Georg,Maria Schneider,Chantip Dang-Heine,Nick Neuwinger,Kai Kappert,Rudolf Tauber,Victor M. Corman,Jan Raabe,Kim Melanie Kaiser,Michael To Vinh,Gereon Rieke,Christian Meisel,Thomas Ulas,Matthias Becker,Robert Geffers,Martin Witzenrath,Christian Drosten,Norbert Suttorp,Christof von Kalle,Florian Kurth,Florian Kurth,Florian Kurth,Kristian Händler,Joachim L. Schultze,Joachim L. Schultze,Anna C. Aschenbrenner,Anna C. Aschenbrenner,Yang Li,Yang Li,Jacob Nattermann,Birgit Sawitzki,Antoine-Emmanuel Saliba,Leif E. Sander,Angel Angelov,Robert Bals,Alexander Bartholomäus,Anke Becker,Daniela Bezdan,Ezio Bonifacio,Peer Bork,Thomas Clavel,Maria Colomé-Tatché,Andreas Diefenbach,Alexander T. Dilthey,Nicole Fischer,Konrad U. Förstner,Julia-Stefanie Frick,Julien Gagneur,Alexander Goesmann,Torsten Hain,Michael Hummel,Stefan Janssen,Jörn Kalinowski,René Kallies,Birte Kehr,Andreas Keller,Sarah Kim-Hellmuth,Christoph Klein,Oliver Kohlbacher,Jan O. Korbel,Ingo Kurth,Kerstin U. Ludwig,Oliwia Makarewicz,Manja Marz,Alice C. McHardy,Christian Mertes,Markus M. Nöthen,Peter Nürnberg,Uwe Ohler,Stephan Ossowski,Jörg Overmann,Silke Peter,Klaus Pfeffer,Anna R. Poetsch,Alfred Pühler,Nikolaus Rajewsky,Markus Ralser,Olaf Rieß,Stephan Ripke,Ulisses Nunes da Rocha,Philip Rosenstiel,Philipp H. Schiffer,Eva-Christina Schulte,Alexander Sczyrba,Oliver Stegle,Jens Stoye,Fabian J. Theis,Janne Vehreschild,Jörg Vogel,Max von Kleist,Andreas Walker,Jörn Walter,Dagmar Wieczorek,John Ziebuhr +137 more
TL;DR: This study provides detailed insights into the systemic immune response to SARS-CoV-2 infection and it reveals profound alterations in the myeloid cell compartment associated with severe COVID-19.
Journal ArticleDOI
Effect of pro-inflammatory and immunoregulatory cytokines on human tenocytes.
Thilo John,Dörte Lodka,Benjamin Kohl,Wolfgang Ertel,Jennifer Jammrath,Claudia Conrad,Christiane Stoll,Catharina Busch,Gundula Schulze-Tanzil +8 more
TL;DR: Results indicate that TNF α strongly activates the tenocytes to amplify their own TNFα expression and, subsequently, that of other regulatory cytokines and matrix degrading enzymes, but the impact of IL‐6 and IL‐10 on tenocytes remains unclear.
Journal ArticleDOI
Healing parameters in a rabbit partial tendon defect following tenocyte/biomaterial implantation.
Christiane Stoll,Thilo John,Claudia Conrad,Anke Lohan,Sylvia Hondke,Wolfgang Ertel,Christian Kaps,Michaela Endres,Michael Sittinger,Jochen Ringe,Gundula Schulze-Tanzil +10 more
TL;DR: A partial Achilles tendon defect model and versatile scoring tools applicable for characterizing biomaterial-supported tendon healing are described.
Journal ArticleDOI
Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice
Philip F. Stahel,Michael A. Flierl,B. Paul Morgan,Ivonne Persigehl,Christiane Stoll,Claudia Conrad,Basel M. Touban,Wade R. Smith,Kathryn Beauchamp,Oliver I Schmidt,Wolfgang Ertel,Iris Leinhase +11 more
TL;DR: An important role of CD59 is emphasized in mediating protection from secondary neuronal cell death and further underscore the key role of the terminal complement pathway in the pathophysiology of traumatic brain injury.
Journal ArticleDOI
Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany.
Tatjana Schwarz,Pinkus Tober-Lau,David Hillus,Elisa T Helbig,Lena J Lippert,Charlotte Thibeault,Willi Koch,Irmgard Landgraf,Janine Michel,Leon Bergfeld,Daniela Niemeyer,Barbara Mühlemann,Claudia Conrad,Chantip Dang-Heine,Stefanie Kasper,Friederike Münn,Kai Kappert,Andreas Nitsche,Rudolf Tauber,Sein Schmidt,Piotr Kopankiewicz,Harald Bias,Joachim Seybold,Christof von Kalle,Terry Jones,Norbert Suttorp,Christian Drosten,Leif E. Sander,Victor M. Corman,Florian Kurth +29 more
TL;DR: In this article, the authors detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers in Germany, and emphasized that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.