Oliver Dietrich

TL;DR: This study provides detailed insights into the systemic immune response to SARS-CoV-2 infection and it reveals profound alterations in the myeloid cell compartment associated with severe COVID-19.

TL;DR: In this paper, the authors reported a case of irreversible BCMA loss in a patient with multiple myeloma who was enrolled in the KarMMa trial and progressed after anti-BCMA CAR T cell therapy and identified selection of a clone with homozygous deletion of TNFRSF17 as the underlying mechanism of immune escape.

TL;DR: This study provides detailed insights into systemic immune response to SARS-CoV-2 infection and it reveals profound alterations in the peripheral myeloid cell compartment associated with severe courses of COVID-19.

TL;DR: Chumduri et al. as mentioned in this paper used single-cell RNA sequencing to characterize epithelial subpopulations and the underlying stromal compartment of endo- and ectocervix, encompassing the transition zone.

TL;DR: In this article , the authors performed single-cell transcriptomic and cell-surface marker profiling of circulating and cardiac immune cells in mice challenged with acute myocardial infarction, and integrated singlecell transcriptomes obtained before and at 1, 3, 5, 7, and 11 days after infarctions.