C
Claudia Pappas
Researcher at Centers for Disease Control and Prevention
Publications - 26
Citations - 5096
Claudia Pappas is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 16, co-authored 20 publications receiving 4820 citations. Previous affiliations of Claudia Pappas include National Center for Immunization and Respiratory Diseases & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans
Rebecca Garten,C. Todd Davis,Colin A. Russell,Colin A. Russell,Bo Shu,Stephen Lindstrom,Amanda Balish,Wendy Sessions,Xiyan Xu,Eugene Skepner,Varough M. Deyde,Margaret Okomo-Adhiambo,Larisa V. Gubareva,John R. Barnes,Catherine B. Smith,Shannon L. Emery,Michael J. Hillman,Pierre Rivailler,James A. Smagala,Miranda de Graaf,Miranda de Graaf,David F. Burke,Ron A. M. Fouchier,Claudia Pappas,Celia Alpuche-Aranda,Hugo López-Gatell,Hiram Olivera,Irma Lopez,Christopher A. Myers,Dennis J. Faix,Patrick J. Blair,Cindy Yu,Kimberly M. Keene,P. David Dotson,David Boxrud,Anthony R. Sambol,Syed H. Abid,Kirsten St. George,Tammy L. Bannerman,Amanda L. Moore,David J. Stringer,Patricia Blevins,Gail J. Demmler-Harrison,Michele Ginsberg,Paula Kriner,Steve Waterman,Sandra Smole,Hugo Guevara,Edward A. Belongia,Patricia A. Clark,Sara T. Beatrice,Ruben O. Donis,Jacqueline M. Katz,Lyn Finelli,Carolyn B. Bridges,Michael W. Shaw,Daniel B. Jernigan,Timothy M. Uyeki,Derek J. Smith,Derek J. Smith,Derek J. Smith,Alexander Klimov,Nancy J. Cox +62 more
TL;DR: The lack of similarity between the 2009 A(H1N1) virus and its nearest relatives indicates that its gene segments have been circulating undetected for an extended period as mentioned in this paper.
Journal ArticleDOI
Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice
Taronna R. Maines,Akila Jayaraman,Jessica A. Belser,Debra A. Wadford,Claudia Pappas,Hui Zeng,Kortney M. Gustin,Melissa B. Pearce,Karthik Viswanathan,Zachary Shriver,Rahul Raman,Nancy J. Cox,Ram Sasisekharan,Jacqueline M. Katz,Terrence M. Tumpey +14 more
TL;DR: In this paper, selected 2009 A(H1N1) influenza isolates were assessed for their ability to cause disease in mice and ferrets and compared with a contemporary seasonal H 1N1 virus for the ability to transmit to naive ferrets through respiratory droplets.
Journal ArticleDOI
A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission
Terrence M. Tumpey,Taronna R. Maines,Neal Van Hoeven,Laurel Glaser,Alicia Solórzano,Claudia Pappas,Claudia Pappas,Nancy J. Cox,David E. Swayne,Peter Palese,Jacqueline M. Katz,Adolfo García-Sastre +11 more
TL;DR: These findings confirm an essential role of hemagglutinin receptor specificity for the transmission of influenza viruses among mammals and suggest that a predominant human α-2,6 sialic acid binding preference is essential for optimal transmission of this pandemic virus.
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Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors
Xiaocong Yu,Tshidi Tsibane,Patricia A. McGraw,Frances S. House,Christopher J. Keefer,Mark D. Hicar,Terrence M. Tumpey,Claudia Pappas,Claudia Pappas,Lucy A. Perrone,Osvaldo Martinez,James Stevens,James Stevens,Ian A. Wilson,Patricia V. Aguilar,Eric Lewin Altschuler,Christopher F. Basler,James E. Crowe +17 more
TL;DR: It is demonstrated that survivors of the 1918 influenza pandemic possess highly functional, virus-neutralizing antibodies to this uniquely virulent virus, and that humans can sustain circulating B memory cells to viruses for many decades after exposure—well into the tenth decade of life.
Journal ArticleDOI
Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air
Neal Van Hoeven,Claudia Pappas,Jessica A. Belser,Taronna R. Maines,Hui Zeng,Adolfo García-Sastre,Ram Sasisekharan,Jacqueline M. Katz,Terrence M. Tumpey +8 more
TL;DR: It is demonstrated that the adaptation of the HA and PB2 proteins are critical for the development of pandemic influenza strains from avian influenza viruses.