M
Miranda de Graaf
Researcher at Erasmus University Rotterdam
Publications - 77
Citations - 8872
Miranda de Graaf is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Norovirus & Virus. The author has an hindex of 30, co-authored 63 publications receiving 7193 citations. Previous affiliations of Miranda de Graaf include Erasmus University Medical Center & University of Cambridge.
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Journal ArticleDOI
Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans
Rebecca Garten,C. Todd Davis,Colin A. Russell,Colin A. Russell,Bo Shu,Stephen Lindstrom,Amanda Balish,Wendy Sessions,Xiyan Xu,Eugene Skepner,Varough M. Deyde,Margaret Okomo-Adhiambo,Larisa V. Gubareva,John R. Barnes,Catherine B. Smith,Shannon L. Emery,Michael J. Hillman,Pierre Rivailler,James A. Smagala,Miranda de Graaf,Miranda de Graaf,David F. Burke,Ron A. M. Fouchier,Claudia Pappas,Celia Alpuche-Aranda,Hugo López-Gatell,Hiram Olivera,Irma Lopez,Christopher A. Myers,Dennis J. Faix,Patrick J. Blair,Cindy Yu,Kimberly M. Keene,P. David Dotson,David Boxrud,Anthony R. Sambol,Syed H. Abid,Kirsten St. George,Tammy L. Bannerman,Amanda L. Moore,David J. Stringer,Patricia Blevins,Gail J. Demmler-Harrison,Michele Ginsberg,Paula Kriner,Steve Waterman,Sandra Smole,Hugo Guevara,Edward A. Belongia,Patricia A. Clark,Sara T. Beatrice,Ruben O. Donis,Jacqueline M. Katz,Lyn Finelli,Carolyn B. Bridges,Michael W. Shaw,Daniel B. Jernigan,Timothy M. Uyeki,Derek J. Smith,Derek J. Smith,Derek J. Smith,Alexander Klimov,Nancy J. Cox +62 more
TL;DR: The lack of similarity between the 2009 A(H1N1) virus and its nearest relatives indicates that its gene segments have been circulating undetected for an extended period as mentioned in this paper.
Journal ArticleDOI
SARS-CoV-2 productively infects human gut enterocytes.
Mart M. Lamers,Joep Beumer,Jelte van der Vaart,Kèvin Knoops,Jens Puschhof,Tim I Breugem,Raimond B. G. Ravelli,J. Paul van Schayck,Anna Z Mykytyn,Hans Duimel,Elly van Donselaar,Samra Riesebosch,Helma J.H. Kuijpers,Debby Schipper,Willine J. van de Wetering,Miranda de Graaf,Marion Koopmans,Edwin Cuppen,Peter J. Peters,Bart L. Haagmans,Hans Clevers +20 more
TL;DR: It is demonstrated that intestinal organoids can serve as a model to understand SARS-CoV-2 biology and infectivity in the gut, and hSIOs serve as an experimental model for coronavirus infection and biology.
Journal ArticleDOI
Genomic Characterization of a Newly Discovered Coronavirus Associated with Acute Respiratory Distress Syndrome in Humans
Sander van Boheemen,Miranda de Graaf,Chris Lauber,Theo M. Bestebroer,V. Stalin Raj,Ali Moh Zaki,Albert D. M. E. Osterhaus,Bart L. Haagmans,Alexander E. Gorbalenya,Alexander E. Gorbalenya,Eric J. Snijder,Ron A. M. Fouchier +11 more
TL;DR: It is proposed that a novel human coronavirus isolated from a man with acute pneumonia and renal failure in June 2012 prototypes a novel species in the genus Betacoronavirus, which is closely related to bat coronaviruses that are distant from SARS-CoV.
Journal ArticleDOI
Updated classification of norovirus genogroups and genotypes
Preeti Chhabra,Miranda de Graaf,Gabriel I. Parra,Martin C.W. Chan,Kim Y. Green,Vito Martella,Qiuhong Wang,Peter A. White,Kazuhiko Katayama,Harry Vennema,Marion Koopmans,Jan Vinjé +11 more
TL;DR: Viruses for which currently only one sequence is available in public databases were classified into tentative new genogroups and genotypes with their definitive assignment awaiting additional related sequences.
Journal ArticleDOI
Role of receptor binding specificity in influenza A virus transmission and pathogenesis
TL;DR: Recent data on the interaction between influenza virus HA and SA receptors of the host, and the impact on virus host range, pathogenesis, and transmission are reviewed and remaining challenges and future research priorities are discussed.