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Claudia T. Silva Aldana
Researcher at Erasmus University Rotterdam
Publications - 3
Citations - 107
Claudia T. Silva Aldana is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: PR interval & Genome-wide association study. The author has an hindex of 2, co-authored 3 publications receiving 76 citations. Previous affiliations of Claudia T. Silva Aldana include Del Rosario University.
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Journal ArticleDOI
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.
Jessica van Setten,Jennifer A. Brody,Yalda Jamshidi,Brenton R. Swenson,Anne M. Butler,Harry Campbell,Fabiola M. Del Greco,Daniel S. Evans,Quince Gibson,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Kathleen F. Kerr,Bouwe P. Krijthe,Leo-Pekka Lyytikäinen,Christian Müller,Martina Müller-Nurasyid,Ilja M. Nolte,Sandosh Padmanabhan,Marylyn D. Ritchie,Antonietta Robino,Albert V. Smith,Albert V. Smith,Maristella Steri,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sheila Ulivi,Niek Verweij,Xiaoyan Yin,David O. Arnar,David O. Arnar,Folkert W. Asselbergs,Folkert W. Asselbergs,Joel S. Bader,John Barnard,J. C. Bis,Stefan Blankenberg,Eric Boerwinkle,Yuki Bradford,Brendan M. Buckley,Mina K. Chung,Dana C. Crawford,Marcel den Hoed,Josh C. Denny,Anna F. Dominiczak,Georg Ehret,Mark Eijgelsheim,Mark Eijgelsheim,Patrick T. Ellinor,Patrick T. Ellinor,Stephan B. Felix,Oscar H. Franco,Lude Franke,Tamara B. Harris,Hilma Holm,Gandin Ilaria,Annamaria Iorio,Mika Kähönen,Ivana Kolcic,Jan A. Kors,Edward G. Lakatta,Lenore J. Launer,Honghuang Lin,Henry J. Lin,Ruth J. F. Loos,Steven A. Lubitz,Steven A. Lubitz,Peter W. Macfarlane,Jared W. Magnani,Irene Mateo Leach,Thomas Meitinger,Braxton D. Mitchell,Thomas Münzel,George J. Papanicolaou,Annette Peters,Arne Pfeufer,Peter P. Pramstaller,Olli T. Raitakari,Jerome I. Rotter,Igor Rudan,Nilesh J. Samani,David Schlessinger,Claudia T. Silva Aldana,Claudia T. Silva Aldana,Moritz F. Sinner,Jonathan D. Smith,Harold Snieder,Elsayed Z. Soliman,Tim D. Spector,David J. Stott,Konstantin Strauch,Kirill V. Tarasov,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,André G. Uitterlinden,David R. Van Wagoner,Uwe Völker,Henry Völzke,Melanie Waldenberger,Harm-Jan Westra,Philipp S. Wild,Tanja Zeller,Alvaro Alonso,Christy L. Avery,Stefania Bandinelli,Emelia J. Benjamin,Francesco Cucca,Marcus Dörr,Luigi Ferrucci,Paolo Gasparini,Vilmundur Gudnason,Caroline Hayward,Susan R. Heckbert,Andrew A. Hicks,J. Wouter Jukema,Stefan Kääb,Terho Lehtimäki,Yongmei Liu,Patricia B. Munroe,Afshin Parsa,Ozren Polasek,Ozren Polasek,Bruce M. Psaty,Bruce M. Psaty,Dan M. Roden,Renate B. Schnabel,Gianfranco Sinagra,Kari Stefansson,Kari Stefansson,Bruno H. Stricker,Pim van der Harst,Cornelia M. van Duijn,James F. Wilson,Sina A. Gharib,Paul I.W. de Bakker,Aaron Isaacs,Dan E. Arking,Nona Sotoodehnia +137 more
TL;DR: Findings implicate developmental pathways, and identify transcription factors, ion-channel genes, and cell-junction/cell-signaling proteins in atrio-ventricular conduction, identifying potential targets for drug development.
Journal ArticleDOI
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits
Jessica van Setten,Niek Verweij,Niek Verweij,Hamdi Mbarek,Maartje N. Niemeijer,Stella Trompet,Dan E. Arking,Jennifer A. Brody,Ilaria Gandin,Niels Grarup,Leanne M. Hall,Leanne M. Hall,Daiane Hemerich,Daiane Hemerich,Leo-Pekka Lyytikäinen,Hao Mei,Martina Müller-Nurasyid,Bram P. Prins,Antonietta Robino,Albert V. Smith,Helen R. Warren,Folkert W. Asselbergs,Folkert W. Asselbergs,Dorret I. Boomsma,Mark J. Caulfield,Mark Eijgelsheim,Mark Eijgelsheim,Ian Ford,Torben Hansen,Tamara B. Harris,Susan R. Heckbert,Jouke-Jan Hottenga,Annamaria Iorio,Jan A. Kors,Allan Linneberg,Allan Linneberg,Peter W. Macfarlane,Thomas Meitinger,Christopher P. Nelson,Christopher P. Nelson,Olli T. Raitakari,Claudia T. Silva Aldana,Claudia T. Silva Aldana,Gianfranco Sinagra,Moritz F. Sinner,Elsayed Z. Soliman,Monika Stoll,André G. Uitterlinden,André G. Uitterlinden,Cornelia M. van Duijn,Melanie Waldenberger,Alvaro Alonso,Paolo Gasparini,Vilmundur Gudnason,Yalda Jamshidi,Stefan Kääb,Jørgen K. Kanters,Terho Lehtimäki,Patricia B. Munroe,Annette Peters,Nilesh J. Samani,Nilesh J. Samani,Nona Sotoodehnia,Sheila Ulivi,James G. Wilson,Eco J. C. de Geus,J. Wouter Jukema,Bruno H. Stricker,Pim van der Harst,Paul I.W. de Bakker,Aaron Isaacs +70 more
TL;DR: A meta-analyzed genome-wide association results from 30,000 mostly Dutch samples on four ECG traits identified seven novel locus-trait associations, demonstrating involvement of cardiac-related pathways and regulation of nearby genes.
Posted ContentDOI
Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity
Jessica van Setten,Jennifer A. Brody,Yalda Jamshidi,Brenton R. Swenson,Anne M. Butler,Harry Campbell,M. Fabiola Del Greco,Daniel S. Evans,Quince Gibson,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Kathleen F. Kerr,Bouwe P. Krijthe,Leo-Pekka Lyytikäinen,Christian Müller,Martina Müller-Nurasyid,Ilja M. Nolte,Sandosh Padmanabhan,Marylyn D. Ritchie,Antonietta Robino,Albert V. Smith,Albert V. Smith,Maristella Steri,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sheila Ulivi,Niek Verweij,Xiaoyan Yin,David O. Arnar,David O. Arnar,Folkert W. Asselbergs,Folkert W. Asselbergs,Joel S. Bader,John Barnard,J. C. Bis,Stefan Blankenberg,Eric Boerwinkle,Yuki Bradford,Brendan M. Buckley,Mina K. Chung,Dana C. Crawford,Marcel den Hoed,Josh C. Denny,Anna F. Dominiczak,Georg Ehret,Mark Eijgelsheim,Mark Eijgelsheim,Patrick T. Ellinor,Patrick T. Ellinor,Stephan B. Felix,Oscar H. Franco,Lude Franke,Tamara B. Harris,Hilma Holm,Gandin Ilaria,Annamaria Iorio,Mika Kähönen,Ivana Kolcic,Jan A. Kors,Edward G. Lakatta,Lenore J. Launer,Honghuang Lin,Henry J. Lin,Ruth J. F. Loos,Steven A. Lubitz,Steven A. Lubitz,Peter W. Macfarlane,Jared W. Magnani,Irene Mateo Leach,Thomas Meitinger,Braxton D. Mitchell,Thomas Münzel,George J. Papanicolaou,Annette Peters,Arne Pfeufer,Peter P. Pramstaller,Olli T. Raitakari,Jerome I. Rotter,Igor Rudan,Nilesh J. Samani,David Schlessinger,Claudia T. Silva Aldana,Moritz F. Sinner,Jonathan D. Smith,Harold Snieder,Elsayed Z. Soliman,Tim D. Spector,David J. Stott,Konstantin Strauch,Kirill V. Tarasov,André G. Uitterlinden,David R. Van Wagoner,Uwe Völker,Henry Völzke,Melanie Waldenberger,Harm-Jan Westra,Philipp S. Wild,Tanja Zeller,Alvaro Alonso,Christy L. Avery,Stefania Bandinelli,Emelia J. Benjamin,Francesco Cucca,Marcus Dörr,Luigi Ferrucci,Paolo Gasparini,Vilmundur Gudnason,Caroline Hayward,Susan R. Heckbert,Andrew A. Hicks,J. Wouter Jukema,Stefan Kääb,Terho Lehtimäki,Yongmei Liu,Patricia B. Munroe,Afshin Parsa,Ozren Polasek,Ozren Polasek,Bruce M. Psaty,Bruce M. Psaty,Dan M. Roden,Renate B. Schnabel,Gianfranco Sinagra,Kari Stefansson,Kari Stefansson,Bruno H. Stricker,Pim van der Harst,Cornelia M. van Duijn,James F. Wilson,Sina A. Gharib,Paul I.W. de Bakker,Aaron Isaacs,Aaron Isaacs,Dan E. Arking,Nona Sotoodehnia +135 more
TL;DR: Findings underscore the power of GWAS to extend knowledge of the molecular underpinnings of clinical processes and identify additional new pleiotropic loci associated with PR interval.