D
Daniel I. Chasman
Researcher at Brigham and Women's Hospital
Publications - 534
Citations - 85313
Daniel I. Chasman is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 134, co-authored 484 publications receiving 72180 citations. Previous affiliations of Daniel I. Chasman include Washington University in St. Louis & Glenfield Hospital.
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Journal ArticleDOI
Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium
Lu-Chen Weng,Lu-Chen Weng,Kathryn L. Lunetta,Martina Müller-Nurasyid,Albert V. Smith,Sébastien Thériault,Sébastien Thériault,Peter Weeke,John Barnard,Joshua C. Bis,Leo-Pekka Lyytikäinen,Marcus E. Kleber,Andreas Martinsson,Henry J. Lin,Henry J. Lin,Michiel Rienstra,Stella Trompet,Bouwe P. Krijthe,Marcus Dörr,Derek Klarin,Daniel I. Chasman,Moritz F. Sinner,Melanie Waldenberger,Lenore J. Launer,Tamara B. Harris,Elsayed Z. Soliman,Alvaro Alonso,Guillaume Paré,Guillaume Paré,Pedro L. Teixeira,Joshua C. Denny,M. Benjamin Shoemaker,David R. Van Wagoner,Jonathan D. Smith,Bruce M. Psaty,Bruce M. Psaty,Nona Sotoodehnia,Nona Sotoodehnia,Kent D. Taylor,Kent D. Taylor,Mika Kähönen,Kjell Nikus,Graciela E. Delgado,Olle Melander,Gunnar Engström,Jie Yao,Jie Yao,Xiuqing Guo,Xiuqing Guo,Ingrid E. Christophersen,Ingrid E. Christophersen,Ingrid E. Christophersen,Patrick T. Ellinor,Patrick T. Ellinor,Bastiaan Geelhoed,Niek Verweij,Peter W. Macfarlane,Ian Ford,Jan Heeringa,Oscar H. Franco,André G. Uitterlinden,Uwe Völker,Alexander Teumer,Lynda M. Rose,Stefan Kääb,Vilmundur Gudnason,Dan E. Arking,David Conen,David Conen,Dan M. Roden,Mina K. Chung,Mina K. Chung,Susan R. Heckbert,Susan R. Heckbert,Emelia J. Benjamin,Terho Lehtimäki,Winfried März,Winfried März,J. Gustav Smith,Jerome I. Rotter,Jerome I. Rotter,Pim van der Harst,J. Wouter Jukema,J. Wouter Jukema,Bruno H. Stricker,Stephan B. Felix,Christine M. Albert,Steven A. Lubitz,Steven A. Lubitz +88 more
TL;DR: The findings suggest that the pathogenesis of AF may differ according to age in individuals of European descent, but there is no evidence of statistically significant genetic interactions with sex, body mass index, or hypertension on AF risk.
Journal ArticleDOI
Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study.
Dov Shiffman,Daniel I. Chasman,Christie M. Ballantyne,Vijay Nambi,James J. Devlin,Eric Boerwinkle +5 more
TL;DR: Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study -
Journal ArticleDOI
Catechol-O-methyltransferase association with hemoglobin A1c.
Kathryn T. Hall,Kathryn T. Hall,Kathleen A. Jablonski,Ling Chen,Maegan Harden,Benjamin R. Tolkin,Ted J. Kaptchuk,Ted J. Kaptchuk,George A. Bray,Paul M. Ridker,Paul M. Ridker,Jose C. Florez,Jose C. Florez,Kenneth J. Mukamal,Kenneth J. Mukamal,Daniel I. Chasman,Daniel I. Chasman +16 more
TL;DR: The directionality of COMT associations was concordant with those previously observed for cardiometabolic risk factors and CVD, and was associated with lower HbA1c and modest protection from type 2 diabetes.
Journal ArticleDOI
Gene variations of ROCKs and risk of ischaemic stroke: the Women’s Genome Health Study
Robert Y. L. Zee,Robert Y. L. Zee,Qing-Mei Wang,Daniel I. Chasman,Paul M. Ridker,James K. Liao +5 more
TL;DR: The findings of the present study suggest that genetic variation within the ROCK-associated pathway gene loci examined, and in particular ROCK1 gene variation, may influence the risk of IsST.
Journal ArticleDOI
Mitochondrial uncoupling protein gene cluster variation (UCP2–UCP3) and the risk of incident type 2 diabetes mellitus: The Women's Genome Health Study
TL;DR: The present investigation suggests that the UCP gene cluster variation may not be a useful predictor for T2DM risk assessment.