D
Daniel I. Chasman
Researcher at Brigham and Women's Hospital
Publications - 534
Citations - 85313
Daniel I. Chasman is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 134, co-authored 484 publications receiving 72180 citations. Previous affiliations of Daniel I. Chasman include Washington University in St. Louis & Glenfield Hospital.
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Journal ArticleDOI
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals
Usman A. Tahir,Daniel H. Katz,Julian Avila-Pachecho,Alexander G. Bick,Akhil Pampana,Jeremy M. Robbins,Zhi Yu,Zsu Zsu Chen,Mark D. Benson,Daniel E. Cruz,Debby Ngo,Shuliang Deng,Xu Shi,S. Zheng,Aaron S. Eisman,Laurie A. Farrell,Michael Wall,Adolfo Correa,Russell P. Tracy,Peter Durda,Kent D. Taylor,Yongmei Liu,W. Craig Johnson,Xiuqing Guo,Jie Yao,Yii-Der Ida Chen,Ani Manichaikul,Frederick L. Ruberg,William S. Blaner,Deepti Jain,Namiko Abe,Gonçalo Abecasis,François Aguet,Christine A Albert,Laura Almasy,Álvaro Alonso,Seth A. Ament,Peter Anderson,Pramod Anugu,Deborah Applebaum-Bowden,Kristin G. Ardlie,Dan E. Arking,Donna K. Arnett,Allison E. Ashley-Koch,Stella Aslibekyan,Tim Assimes,Paul L. Auer,Dimitrios Avramopoulos,Najib T. Ayas,Adithya Balasubramanian,John Barnard,Kathleen C. Barnes,R. Graham Barr,Emily Barron-Casella,Lucas Barwick,Terri H. Beaty,Gerald Beck,Diane M. Becker,Lewis C. Becker,Rebecca L. Beer,Amber L. Beitelshees,Emelia J. Benjamin,Takis Benos,Marcos Bezerra,Lawrence F. Bielak,Joshua A Bis,Thomas W. Blackwell,John Blangero,Nathan R. Blue,Eric Boerwinkle,Donald W. Bowden,Russell P. Bowler,Jennifer A. Brody,Ulrich Broeckel,Jai G. Broome,Deborah L. Brown,Karen L. Bunting,Esteban G. Burchard,Carlos Bustamante,Erin J Buth,Brian E. Cade,Jonathan Cardwell,Vincent J. Carey,Julie Carrier,April P. Carson,Cara L. Carty,Richard Casaburi,Juan Pablo Casas Romero,James M. Casella,Peter J. Castaldi,Mark Chaffin,Christy Y. P. Chang,Yi-Cheng Chang,Daniel I. Chasman,Sameer Chavan,Bo Chen,Wei-Min Chen,Mi Ae Cho,Seung Hoan Choi,Lee-Ming Chuang,M Chung,Ren-Hua Chung,Suzy A. A. Comhair,Matthew P. Conomos,Elaine Cornell,Carolyn J. Crandall,J. A. Crapo,L. Adrienne Cupples,Joanne E. Curran,Jeffrey R. Curtis,Brian Custer,Coleen M. Damcott,Dawood Darbar,Sean David,Colleen P. Davis,Michelle Daya,Mariza de Andrade,Lisa De Las Fuentes,Paul S. de Vries,Michael DeBaun,Ranjan Deka,Dawn L. DeMeo,Scott Devine,Huyen Dinh,Harshavardhan Doddapaneni,Qing Duan,Shannon Dugan-Perez,Ravindranath Duggirala,Susan K. Dutcher,Charles B. Eaton,Lynette Ekunwe,A. El Boueiz,Patrick T. Ellinor,Leslie S. Emery,Serpil C. Erzurum,Charles D. Farber,Jesse Farek,Tasha E. Fingerlin,Matthew Flickinger,Myriam Fornage,Nora Franceschini,Christian D. Frazar,Mao Fu,Stephanie M. Fullerton,Lucinda Fulton,Stacey Gabriel,Weiniu Gan,Shanshan Gao,Yan Gao,Margery Gass,Heather Geiger,Bruce Gelb,M. Geraci,Soren Germer,Auyon J. Ghosh,Richard Gibbs,Christopher R. Gignoux,M. Ruban Gladwin,David E. Glahn,Stephanie M. Gogarten,Da-Wei Gong,Harald H.H. Gőring,Sharon L. Graw,Kathryn J. Gray,Daniel Grine,Colin Gross,C. Charles Gu,Yue Guan,Namrata Gupta,Jeffrey Haessler,Yi Han,Patrick J. Hanly,Daniel N. Harris,Nicola L. Hawley,Jiang He,Benjamin D. Heavner,Susan R. Heckbert,Ryan Christopher Hernandez,David Herrington,Craig P. Hersh,Bertha Hidalgo,James E. Hixson,Brian D. Hobbs,John Hokanson,Elliot Hong,Karin F. Hoth,Chao-Ti Hsiung,Jianhong Hu,Yi Jen Hung,Haley Huston,Chii-Min Hwu,Marguerite R. Irvin,Rebecca D. Jackson,Cashell E. Jaquish,Jill M. Johnsen,Andrew Johnson,Richard Karl. Johnston,Kimberly Jones,Hyun Min Kang,Robert Kaplan,Sharon L.R. Kardia,Shannon Jeanne Kelly,Eimear E. Kenny,Michael Kessler,Alyna T. Khan,Ziad Khan,Wonji Kim,John Kimoff,Greg Kinney,Barbara A. Konkle,Charles Kooperberg,Holly B. Kramer,Christoph Lange,Ethan M. Lange,Leslie A. Lange,Cathy C. Laurie,Cecelia A. Laurie,Meryl S. LeBoff,Jiwon Lee,Sandra L. Lee,Wen-Jane Lee,Jonathon LeFaive,David K. Levine,Daniel Levy,Joshua P. Lewis,Xiaohui Li,Yun Li,Henry J. Lin,Honghuang Lin,Xihong Lin,Simin Liu,Yu Liu,Ruth J. F. Loos,Steven A. Lubitz,Kathryn L. Lunetta,James Luo,Ulysses J. Magalang,Michael P. Mahaney,Barry J. Make,Alisa K. Manning,Joanna Manson,Lisa A. Martin,Melissa A. Marton,Susan Mathai,Rasika A. Mathias,Susanne May,Patrick F. McArdle,M. McDonald,Sean K. McFarland,Stephen T. McGarvey,Daniel J. McGoldrick,Caitlin P. McHugh,Becky McNeil,Hao Mei,James B. Meigs,Vipin Menon,Luisa Mestroni,Ginger A. Metcalf,Deborah A. Meyers,Emmanuel Mignot,Julie L. Mikulla,Nancy Min,Mollie A. Minear,Ryan L. Minster,Braxton D. Mitchell,Matthew Moll,Zeineen Momin,May E. Montasser,Courtney G. Montgomery,Donna M. Muzny,Josyf C. Mychaleckyj,Girish N. Nadkarni,Rakhi Naik,Take Naseri,Sergei Nekhai,Sarah C. Nelson,Bonnie Neltner,Caitlin E. Nessner,Deborah A. Nickerson,Osuji Nkechinyere,Kari E. North,Jeffrey R. O'Connell,T. O’Connor,Heather M. Ochs-Balcom,Geoffrey Okwuonu,Allan I. Pack,David T. Paik,Nicholette D. Palmer,James S. Pankow,George J. Papanicolaou,Cora Parker,Gina M. Peloso,Juan M. Peralta,Marco V Perez,James C. Perry,Ulrike Peters,Patricia A. Peyser,L. Phillips,Jacob Pleiness,Toni I. Pollin,Wendy S. Post,Julia Powers Becker,Meher Preethi Boorgula,Michael Preuss,Bruce M. Psaty,Pankaj Qasba,Dandi Qiao,Zhaohui S. Qin,Nicholas Rafaels,Laura M. Raffield,Mahitha Rajendran,Vasan S. Ramachandran,Dabeeru C. Rao,Laura J. Rasmussen-Torvik,Aakrosh Ratan,Susan Redline,Robert M. Reed,Catherine Reeves,E. Regan,Alexander P. Reiner,Muagututi‘a Sefuiva Reupena,Kenneth Rice,Rébecca Robillard,Nicolas Robine,Dan Roden,Carolina Roselli,Ingo Ruczinski,Alexi M Runnels,Pamela Russell,Sarah E. Ruuska,Ester Cerdeira Sabino,Danish Saleheen,Shabnam Salimi,Sejal Salvi,Steven L. Salzberg,Kevin Sandow,Vijay G. Sankaran,Jireh Santibanez,Karen Schwander,David A. Schwartz,Frank C. Sciurba,Christine E. Seidman,Jonathan Seidman,Frédéric Sériès,Vivien A. Sheehan,Stephanie Sherman,Amol C. Shetty,Aniket Shetty,Wayne H-H Sheu,M. Benjamin Shoemaker,Brian H. Silver,Edwin K. Silverman,Robert Skomro,Jennifer A. Smith,Josh Smith,Nicholas L. Smith,Tanja Smith,Sylvia Smoller,Beverly M. Snively,Michael Snyder,Tamar Sofer,Nona Sotoodehnia,Adrienne M. Stilp,Garrett R. Storm,Elizabeth A. Streeten,Jessica Lasky-Su,Yun Ju Sung,Jody S. Sylvia,Adam A. Szpiro,Daniel Taliun,Hua Tang,Margaret A. Taub,Matthew D. Taylor,Simeon I. Taylor,Marilyn I. Telen,Timothy A. Thornton,M. Threlkeld,Lesley F. Tinker,David L. Tirschwell,Sarah A. Tishkoff,Hemant K. Tiwari,Catherine Tong,Michael Y. Tsai,Dhananjay Vaidya,David Van Den Berg,Peter VandeHaar,Scott I. Vrieze,Tarik Walker,Robert B. Wallace,Avram D. Walts,Fei Fei Wang,Heming Wang,Jiongming Wang,Karol E. Watson,Jennifer Watt,Daniel E. Weeks,Joshua S. Weinstock,Bruce Weir,Scott T. Weiss,Lu-Chen Weng,Jennifer Wessel,Cristen J. Willer,Kayleen Williams,L. Keoki Williams,Carla Wilson,Lara Heermans Winterkorn,Quenna Wong,Joseph C. Wu,Huichun Xu,Lisa R. Yanek,Ivana V. Yang,Ketian Yu,Seyedeh M. Zekavat,Yingze Zhang,Snow Xueyan Zhao,Wei Zhao,Xiaofeng Zhu,Elad Ziv,Michael C. Zody,Sebastian Zoellner,Claude Bouchard,Mark A. Sarzynski,Stephen S. Rich,Jerome I. Rotter,Thomas J. Wang,James F. Wilson,Clary B. Clish,Pradeep Natarajan,Robert E. Gerszten +428 more
TL;DR: The authors performed a whole genome association study of 2,291 metabolite peaks (known and unknown features) in 2,466 Black individuals from the Jackson Heart Study and identified 519 locus-metabolite associations for 427 metabolites and validated their findings in two multi-ethnic cohorts.
Journal ArticleDOI
Migraine, Stroke, and Cervical Arterial Dissection
Iyas Daghals,Muralidharan Sargurupremraj,Rebecca D Danning,Padhraig Gormley,Rainer Malik,Philippe Amouyel,Tiina M. Metso,Alessandro Pezzini,Tobias Kurth,Stéphanie Debette,Daniel I. Chasman +10 more
TL;DR: The findings emphasize shared genetic risk between migraine and CeAD while identifying loci with likely vascular function in migraine and shared but opposite genetic riskBetween migraine and stroke subtypes, and a central role of LRP1 in all 3 cerebrovascular disorders.
Journal ArticleDOI
Gene-Based Elevated Triglycerides and Type 2 Diabetes Mellitus Risk in the Women's Genome Health Study.
Shafqat Ahmad,Shafqat Ahmad,Shafqat Ahmad,Samia Mora,Paul M. Ridker,Frank B. Hu,Frank B. Hu,Daniel I. Chasman +7 more
TL;DR: The results confirm the previous observations of the paradoxical associations of TG with type 2 diabetes mellitus while focusing attention on the larger TG-rich lipoprotein particle subfractions, suggesting their importance in clinical profiling of T2DM risk.
Journal ArticleDOI
Understanding AAA Pathobiology: A GWAS Leads the Way.
TL;DR: The liability to AAA has been shown to be as high as >70% heritable enabling refinement of the similarities and differences with CAD through genetic analysis, and genetic analysis of complex traits such as AAA can be investigated in an unbiased way using the genome-wide association study (GWAS) approach.