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Daniel I. Chasman

Researcher at Brigham and Women's Hospital

Publications -  534
Citations -  85313

Daniel I. Chasman is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 134, co-authored 484 publications receiving 72180 citations. Previous affiliations of Daniel I. Chasman include Washington University in St. Louis & Glenfield Hospital.

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Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults

Mariaelisa Graff, +349 more
- 27 Apr 2017 - 
TL;DR: In additional genome-wide meta-analyses adjusting for PA and interaction with PA, 11 novel adiposity loci are identified, suggesting that accounting for PA or other environmental factors that contribute to variation in adiposity may facilitate gene discovery.
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Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3.

TL;DR: This study evaluated 9p21.3 polymorphism and more conventional cardiovascular risk factors in 22129 white, female health professionals followed for a median of 10 years and found that addition of the genetic information did not improve clinical classification of a woman's risk for cardiovascular disease.

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Georg Ehret, +312 more
TL;DR: The 66-SNP blood pressure risk score was significantly associated with target organ damage in multiple tissues but with minor effects in the kidney, expanding current knowledge of blood pressure–related pathways and highlighting tissues beyond the classical renal system in blood pressure regulation.
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Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

Yukinori Okada, +414 more
- 01 Aug 2012 - 
TL;DR: A meta-analysis of genome-wide association studies for kidney function–related traits, including 71,149 east Asian individuals from 18 studies in 11 population-, hospital- or family-based cohorts, conducted as part of the Asian Genetic Epidemiology Network (AGEN), identified 17 loci newly associated with kidney function-related traits.

Exome-wide association study of plasma lipids in > 300,000 individuals

Dajiang J. Liu, +226 more