D
Daniel I. Chasman
Researcher at Brigham and Women's Hospital
Publications - 534
Citations - 85313
Daniel I. Chasman is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 134, co-authored 484 publications receiving 72180 citations. Previous affiliations of Daniel I. Chasman include Washington University in St. Louis & Glenfield Hospital.
Papers
More filters
Journal ArticleDOI
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
John R. B. Perry,Felix R. Day,Cathy E. Elks,Patrick Sulem,Deborah J. Thompson,Teresa Ferreira,Chunyan He,Daniel I. Chasman,Tõnu Esko,Tõnu Esko,Gudmar Thorleifsson,Eva Albrecht,Wei Ang,Tanguy Corre,Tanguy Corre,Diana L. Cousminer,Bjarke Feenstra,Nora Franceschini,Andrea Ganna,Andrew D. Johnson,Sanela Kjellqvist,Kathryn L. Lunetta,George McMahon,Ilja M. Nolte,Lavinia Paternoster,Eleonora Porcu,Albert V. Smith,Lisette Stolk,Alexander Teumer,Natalia Tšernikova,Emmi Tikkanen,Sheila Ulivi,Erin K. Wagner,Najaf Amin,Laura J. Bierut,Enda M. Byrne,Enda M. Byrne,Jouke-Jan Hottenga,Daniel L. Koller,Massimo Mangino,Tune H. Pers,Tune H. Pers,Tune H. Pers,Laura M. Yerges-Armstrong,Jing Hua Zhao,Irene L. Andrulis,Hoda Anton-Culver,Femke Atsma,Stefania Bandinelli,Matthias W. Beckmann,Javier Benitez,Carl Blomqvist,Stig E. Bojesen,Manjeet K. Bolla,Bernardo Bonanni,Hiltrud Brauch,Hiltrud Brauch,Hermann Brenner,Julie E. Buring,Jenny Chang-Claude,Stephen J. Chanock,Jinhui Chen,Georgia Chenevix-Trench,J. Margriet Collée,Fergus J. Couch,David Couper,Andrea D. Coviello,Angela Cox,Kamila Czene,Adamo Pio D'Adamo,George Davey Smith,Immaculata De Vivo,Ellen W. Demerath,Joe Dennis,Peter Devilee,Aida Karina Dieffenbach,Alison M. Dunning,Gudny Eiriksdottir,Johan G. Eriksson,Johan G. Eriksson,Peter A. Fasching,Luigi Ferrucci,Dieter Flesch-Janys,Henrik Flyger,Tatiana Foroud,Lude Franke,Melissa E. Garcia,Montserrat Garcia-Closas,Frank Geller,Eco de Geus,Graham G. Giles,Graham G. Giles,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Vilmundur Gudnason,Pascal Guénel,Suiqun Guo,Per Hall,Ute Hamann,Robin Haring,Catharina A. Hartman,Andrew C. Heath,Albert Hofman,Maartje J. Hooning,John L. Hopper,Frank B. Hu,David J. Hunter,David Karasik,Douglas P. Kiel,Julia A. Knight,Veli-Matti Kosma,Zoltán Kutalik,Zoltán Kutalik,Sandra Lai,Diether Lambrechts,Annika Lindblom,Reedik Mägi,Patrik K. E. Magnusson,Arto Mannermaa,Nicholas G. Martin,Gisli Masson,Patrick F. McArdle,Wendy L. McArdle,Mads Melbye,Mads Melbye,Kyriaki Michailidou,Evelin Mihailov,Lili Milani,Roger L. Milne,Roger L. Milne,Heli Nevanlinna,Patrick Neven,Ellen A. Nohr,Albertine J. Oldehinkel,Ben A. Oostra,Aarno Palotie,Aarno Palotie,Aarno Palotie,Munro Peacock,Nancy L. Pedersen,Paolo Peterlongo,Julian Peto,Paul D.P. Pharoah,Dirkje S. Postma,Anneli Pouta,Anneli Pouta,Katri Pylkäs,Paolo Radice,Susan M. Ring,Fernando Rivadeneira,Antonietta Robino,Lynda M. Rose,Anja Rudolph,Veikko Salomaa,Serena Sanna,David Schlessinger,Marjanka K. Schmidt,Mellissa C. Southey,Ulla Sovio,Ulla Sovio,Meir J. Stampfer,Doris Stöckl,Anna Maria Storniolo,Nicholas J. Timpson,Jonathan Tyrer,Jenny A. Visser,Peter Vollenweider,Henry Völzke,Gérard Waeber,Melanie Waldenberger,Henri Wallaschofski,Qin Wang,Gonneke Willemsen,Robert Winqvist,Bruce H. R. Wolffenbuttel,Margaret J. Wright,Dorret I. Boomsma,Michael J. Econs,Kay-Tee Khaw,Ruth J. F. Loos,Ruth J. F. Loos,Mark I. McCarthy,Grant W. Montgomery,John P. Rice,Elizabeth A. Streeten,Elizabeth A. Streeten,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Cornelia M. van Duijn,Behrooz Z. Alizadeh,Sven Bergmann,Sven Bergmann,Eric Boerwinkle,Heather A. Boyd,Laura Crisponi,Paolo Gasparini,Christian Gieger,Tamara B. Harris,Erik Ingelsson,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Peter Kraft,Debbie A Lawlor,Andres Metspalu,Craig E. Pennell,Paul M. Ridker,Harold Snieder,Thorkild I. A. Sørensen,Tim D. Spector,David P. Strachan,André G. Uitterlinden,Nicholas J. Wareham,Elisabeth Widen,Marek Zygmunt,Anna Murray,Douglas F. Easton,Kari Stefansson,Kari Stefansson,Joanne M. Murabito,Ken K. Ong +220 more
TL;DR: In this article, the authors used genome-wide and custom-genotyping arrays in up to 182,416 women of European descent from 57 studies and found robust evidence for 123 signals at 106 genomic loci associated with age at menarche.
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
Anna Koettgen,Eva Albrecht,Alexander Teumer,Veronique Vitart,Jan Krumsiek,Claudia Hundertmark,Giorgio Pistis,Daniela Ruggiero,Conall M. O'Seaghdha,Toomas Haller,Qiong Yang,Toshiko Tanaka,Andrew D. Johnson,Zoltán Kutalik,Albert V. Smith,Julia Shi,Maksim Struchalin,Rita P. S. Middelberg,Morris J. Brown,Angelo L. Gaffo,Nicola Pirastu,Guo Li,Caroline Hayward,Tatijana Zemunik,Jennifer E. Huffman,Loic Yengo,Jing Hua Zhao,Ayse Demirkan,Mary F. Feitosa,Xuan Liu,Giovanni Malerba,Lorna M. Lopez,Pim van der Harst,Xinzhong Li,Marcus E. Kleber,Andrew A. Hicks,Ilja M. Nolte,Åsa Johansson,Federico Murgia,Sarah H. Wild,Stephan J. L. Bakker,John F. Peden,Abbas Dehghan,Maristella Steri,Albert Tenesa,Vasiliki Lagou,Perttu Salo,Massimo Mangino,Lynda M. Rose,Terho Lehtimäki,Owen M. Woodward,Yukinori Okada,Adrienne Tin,Christian Mueller,Christopher Oldmeadow,Margus Putku,Darina Czamara,Peter Kraft,Laura Frogheri,Gian Andri Thun,Anne Grotevendt,Gauti Kjartan Gislason,Tamara B. Harris,Lenore J. Launer,Patrick F. McArdle,Alan R. Shuldiner,Eric Boerwinkle,Josef Coresh,Helena Schmidt,Michael Schallert,Nicholas G. Martin,Grant W. Montgomery,Michiaki Kubo,Yusuke Nakamura,Toshihiro Tanaka,Patricia B. Munroe,Nilesh J. Samani,David R. Jacobs,Kiang Liu,Pio D'Adamo,Sheila Ulivi,Jerome I. Rotter,Bruce M. Psaty,Peter Vollenweider,Gérard Waeber,Susan Campbell,Olivier Devuyst,Pau Navarro,Ivana Kolcic,Nicholas D. Hastie,Beverley Balkau,Philippe Froguel,Tõnu Esko,Andres Salumets,Kay-Tee Khaw,Claudia Langenberg,Nicholas J. Wareham,Aaron Isaacs,Aldi T. Kraja,Qunyuan Zhang,Philipp S. Wild,Rodney J. Scott,Elizabeth G. Holliday,Elin Org,Margus Viigimaa,Stefania Bandinelli,Jeffrey Metter,Antonio Lupo,Elisabetta Trabetti,Rossella Sorice,Angela Doering,Eva Lattka,Konstantin Strauch,Fabian J. Theis,Melanie Waldenberger,H-Erich Wichmann,Gail Davies,Alan J. Gow,Marcel Bruinenberg,Ronald P. Stolk,Jaspal S. Kooner,Weihua Zhang,Bernhard R. Winkelmann,Bernhard O. Boehm,Susanne Lucae,Brenda W.J.H. Penninx,Johannes H. Smit,Gary C. Curhan,Poorva Mudgal,Robert M. Plenge,Laura Portas,Ivana Persico,Mirna Kirin,James F. Wilson,Irene Mateo Leach,Wiek H. van Gilst,Anuj Goel,Halit Ongen,Albert Hofman,Fernando Rivadeneira,André G. Uitterlinden,Medea Imboden,Arnold von Eckardstein,Francesco Cucca,Ramaiah Nagaraja,Maria Grazia Piras,Matthias Nauck,Claudia Schurmann,Kathrin Budde,Florian Ernst,Susan M. Farrington,Evropi Theodoratou,Inga Prokopenko,Michael Stumvoll,Antti Jula,Markus Perola,Veikko Salomaa,So-Youn Shin,Tim D. Spector,Cinzia Sala,Paul M. Ridker,Mika Kaehoenen,Jorma Viikari,Christian Hengstenberg,Christopher P. Nelson,James F. Meschia,Mike A. Nalls,Pankaj Sharma,Andrew B. Singleton,Naoyuki Kamatani,Tanja Zeller,Michel Burnier,John Attia,Maris Laan,Norman Klopp,Hans L. Hillege,Stefan Kloiber,Hyon K. Choi,Mario Pirastu,Silvia Tore,Nicole Probst-Hensch,Henry Voelzke,Vilmundur Gudnason,Afshin Parsa,Reinhold E. Schmidt,John Whitfield,Myriam Fornage,Paolo Gasparini,David S. Siscovick,Ozren Polasek,Harry Campbell,Igor Rudan,Nabila Bouatia-Naji,Andres Metspalu,Ruth J. F. Loos,Cornelia M. van Duijn,Ingrid B. Borecki,Luigi Ferrucci,Giovanni Gambaro,Ian J. Deary,Bruce H. R. Wolffenbuttel,John C. Chambers,Winfried Maerz,Peter P. Pramstaller,Harold Snieder,Ulf Gyllensten,Alan F. Wright,Gerjan Navis,Hugh Watkins,Jacqueline C.M. Witteman,Serena Sanna,Sabine Schipf,Malcolm G. Dunlop,Anke Toenjes,Samuli Ripatti,Nicole Soranzo,Daniela Toniolo,Daniel I. Chasman,Olli T. Raitakari,W. H. Linda Kao,Marina Ciullo,Caroline S. Fox,Mark J. Caulfield,Murielle Bochud,Christian Gieger +224 more
TL;DR: In this article, the authors identified and replicated 28 genome-wide significant loci in association with serum urate concentrations (18 new regions in or near TRIM46, INHBB, SFMBT1, TMEM171, VEGFA, BAZ1B, PRKAG2, STC1, HNF4G, A1CF, ATXN2, UBE2Q2, IGF1R, NFAT5, MAF, HLF, ACVR1B-ACVRL1 and B3GNT4).
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Sonja I. Berndt,Stefan Gustafsson,Reedik Maegi,Andrea Ganna,Eleanor Wheeler,Mary F. Feitosa,Anne E. Justice,Keri L. Monda,Damien C. Croteau-Chonka,Felix R. Day,Tõnu Esko,Tove Fall,Teresa Ferreira,Davide Gentilini,Anne U. Jackson,Jian'an Luan,Joshua C. Randall,Sailaja Vedantam,Cristen J. Willer,Thomas W. Winkler,Andrew R. Wood,Tsegaselassie Workalemahu,Yi-Juan Hu,Sang Hong Lee,Liming Liang,Danyu Lin,Josine L. Min,Benjamin M. Neale,Gudmar Thorleifsson,Jian Yang,Eva Albrecht,Najaf Amin,Jennifer L. Bragg-Gresham,Gemma Cadby,Martin den Heijer,Niina Eklund,Krista Fischer,Anuj Goel,Jouke-Jan Hottenga,Jennifer E. Huffman,Ivonne Jarick,Åsa Johansson,Toby Johnson,Stavroula Kanoni,Marcus E. Kleber,Inke R. Koenig,Kati Kristiansson,Z. Kutalik,Claudia Lamina,Cécile Lecoeur,Guo Li,Massimo Mangino,Wendy L. McArdle,Carolina Medina-Gomez,Martina Mueller-Nurasyid,Julius S. Ngwa,Ilja M. Nolte,Lavinia Paternoster,Sonali Pechlivanis,Markus Perola,Marjolein Peters,Michael Preuss,Lynda M. Rose,Jianxin Shi,Dmitry Shungin,Albert V. Smith,Rona J. Strawbridge,Ida Surakka,Alexander Teumer,Mieke D. Trip,Jonathan Tyrer,Jana V. van Vliet-Ostaptchouk,Liesbeth Vandenput,Lindsay L. Waite,Jing Hua Zhao,Devin Absher,Folkert W. Asselbergs,Mustafa Atalay,Antony P. Attwood,Anthony J. Balmforth,Hanneke Basart,John Beilby,Lori L. Bonnycastle,Paolo Brambilla,Marcel Bruinenberg,Harry Campbell,Daniel I. Chasman,Peter S. Chines,Francis S. Collins,John M. C. Connell,William O.C.M. Cookson,Ulf de Faire,Femmie de Vegt,Mariano Dei,Maria Dimitriou,Sarah Edkins,Karol Estrada,David M. Evans,Martin Farrall,Marco M Ferrario,Jean Ferrières,Lude Franke,Francesca Frau,Pablo V. Gejman,Harald Grallert,Henrik Groenberg,Vilmundur Gudnason,Alistair S. Hall,Per Hall,Anna-Liisa Hartikainen,Caroline Hayward,Nancy L. Heard-Costa,Andrew Heath,Johannes Hebebrand,Georg Homuth,Frank B. Hu,Sarah E. Hunt,Elina Hyppoenen,Carlos Iribarren,Kevin B. Jacobs,John-Olov Jansson,Antti Jula,Mika Kähönen,Sekar Kathiresan,Frank Kee,Kay-Tee Khaw,Mika Kivimäki,Wolfgang Koenig,Aldi T. Kraja,Meena Kumari,Kari Kuulasmaa,Johanna Kuusisto,Jaana Laitinen,Timo A. Lakka,Claudia Langenberg,Lenore J. Launer,Lars Lind,Jaana Lindström,Jianjun Liu,Antonio Liuzzi,Marja-Liisa Lokki,Mattias Lorentzon,Pamela A. F. Madden,Patrik K. E. Magnusson,Paolo Manunta,Diana Marek,Winfried Maerz,Irene Mateo Leach,Barbara McKnight,Sarah E. Medland,Evelin Mihailov,Lili Milani,Grant W. Montgomery,Vincent Mooser,Thomas W. Muehleisen,Patricia B. Munroe,Arthur W. Musk,Narisu Narisu,Gerjan Navis,George Nicholson,Ellen A. Nohr,Ken K. Ong,Ben A. Oostra,Colin N. A. Palmer,Aarno Palotie,John F. Peden,Nancy L. Pedersen,Annette Peters,Ozren Polasek,Anneli Pouta,Peter P. Pramstaller,Inga Prokopenko,Carolin Puetter,Aparna Radhakrishnan,Olli T. Raitakari,Augusto Rendon,Fernando Rivadeneira,Igor Rudan,Timo Saaristo,Jennifer G. Sambrook,Alan R. Sanders,Serena Sanna,Jouko Saramies,Sabine Schipf,Stefan Schreiber,Heribert Schunkert,So-Youn Shin,Stefano Signorini,Juha Sinisalo,Boris Skrobek,Nicole Soranzo,Alena Stančáková,Klaus Stark,Jonathan Stephens,Kathleen Stirrups,Ronald P. Stolk,Michael Stumvoll,Amy J. Swift,Eirini V. Theodoraki,Barbara Thorand,David-Alexandre Trégouët,Elena Tremoli,Melanie M. van der Klauw,Joyce B. J. van Meurs,Sita H. Vermeulen,Jorma Viikari,Jarmo Virtamo,Veronique Vitart,Gérard Waeber,Zhaoming Wang,Elisabeth Widen,Sarah H. Wild,Gonneke Willemsen,Bernhard R. Winkelmann,Jacqueline C.M. Witteman,Bruce H. R. Wolffenbuttel,Andrew Wong,Alan F. Wright,M. Carola Zillikens,Philippe Amouyel,Bernhard O. Boehm,Eric Boerwinkle,Dorret I. Boomsma,Mark J. Caulfield,Stephen J. Chanock,L. Adrienne Cupples,Daniele Cusi,George Dedoussis,Jeanette Erdmann,Johan G. Eriksson,Paul W. Franks,Philippe Froguel,Christian Gieger,Ulf Gyllensten,Anders Hamsten,Tamara B. Harris,Christian Hengstenberg,Andrew A. Hicks,Aroon D. Hingorani,Anke Hinney,Albert Hofman,Kees Hovingh,Kristian Hveem,Thomas Illig,Marjo-Riitta Järvelin,Karl-Heinz Joeckel,Sirkka Keinänen-Kiukaanniemi,Lambertus A. Kiemeney,Diana Kuh,Markku Laakso,Terho Lehtimäki,Douglas F. Levinson,Nicholas G. Martin,Andres Metspalu,Andrew D. Morris,Markku S. Nieminen,Inger Njølstad,Claes Ohlsson,Albertine J. Oldehinkel,Willem H. Ouwehand,Lyle J. Palmer,Brenda W.J.H. Penninx,Chris Power,Michael A. Province,Bruce M. Psaty,Lu Qi,Rainer Rauramaa,Paul M. Ridker,Samuli Ripatti,Veikko Salomaa,Nilesh J. Samani,Harold Snieder,Thorkild I. A. Sørensen,Tim D. Spector,Kari Stefansson,Anke Tönjes,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,Pim van der Harst,Peter Vollenweider,Henri Wallaschofski,Nicholas J. Wareham,Hugh Watkins,H-Erich Wichmann,James F. Wilson,Gonçalo R. Abecasis,Themistocles L. Assimes,Inês Barroso,Michael Boehnke,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Timothy M. Frayling,Leif Groop,Talin Haritunian,Iris M. Heid,David J. Hunter,Robert C. Kaplan,Fredrik Karpe,Miriam F. Moffatt,Karen L. Mohlke,Jeffrey R. O'Connell,Yudi Pawitan,Eric E. Schadt,David Schlessinger,Valgerdur Steinthorsdottir,David P. Strachan,Unnur Thorsteinsdottir,Cornelia M. van Duijn,Peter M. Visscher,Anna Maria Di Blasio,Joel N. Hirschhorn,Cecilia M. Lindgren,Andrew P. Morris,David Meyre,Andr Scherag,Mark I. McCarthy,Elizabeth K. Speliotes,Kari E. North,Ruth J. F. Loos,Erik Ingelsson +321 more
Journal ArticleDOI
Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation
Carolina Roselli,Mark Chaffin,Lu-Chen Weng,Lu-Chen Weng,Stefanie Aeschbacher,Gustav Ahlberg,Christine M. Albert,Peter Almgren,Alvaro Alonso,Christopher D. Anderson,Christopher D. Anderson,Krishna G. Aragam,Krishna G. Aragam,Dan E. Arking,John Barnard,Traci M. Bartz,Emelia J. Benjamin,Emelia J. Benjamin,Nathan A. Bihlmeyer,Joshua C. Bis,Heather L. Bloom,Eric Boerwinkle,Erwin B. Bottinger,Jennifer A. Brody,Hugh Calkins,Archie Campbell,Thomas P. Cappola,John F. Carlquist,John F. Carlquist,Daniel I. Chasman,Daniel I. Chasman,Lin Y. Chen,Yii-Der Ida Chen,Eue Keun Choi,Seung Hoan Choi,Ingrid E. Christophersen,Ingrid E. Christophersen,Ingrid E. Christophersen,Mina K. Chung,John W. Cole,John W. Cole,David Conen,David Conen,James P. Cook,Harry J.G.M. Crijns,Michael J. Cutler,Scott M. Damrauer,Scott M. Damrauer,Brian R. Daniels,Dawood Darbar,Graciela Delgado,Joshua C. Denny,Martin Dichgans,Martin Dichgans,Marcus Dörr,Elton A. M. P. Dudink,Samuel C. Dudley,Nada Esa,Tõnu Esko,Tõnu Esko,Markku Eskola,Diane Fatkin,Diane Fatkin,Diane Fatkin,Stephan B. Felix,Ian Ford,Oscar H. Franco,Bastiaan Geelhoed,Raji P. Grewal,Raji P. Grewal,Vilmundur Gudnason,Xiuqing Guo,Namrata Gupta,Stefan Gustafsson,Rebecca Gutmann,Anders Hamsten,Tamara B. Harris,Caroline Hayward,Susan R. Heckbert,Susan R. Heckbert,Jussi Hernesniemi,Lynne J. Hocking,Albert Hofman,Andrea R. V. R. Horimoto,Jie Huang,Paul L. Huang,Jennifer E. Huffman,Erik Ingelsson,Erik Ingelsson,Esra Gucuk Ipek,Kaoru Ito,Jordi Jimenez-Conde,Jordi Jimenez-Conde,Renee Johnson,J. Wouter Jukema,Stefan Kääb,Mika Kähönen,Yoichiro Kamatani,John P. Kane,Adnan Kastrati,Sekar Kathiresan,Sekar Kathiresan,Petra Katschnig-Winter,Maryam Kavousi,Thorsten Kessler,Bas L.J.H. Kietselaer,Paulus Kirchhof,Marcus E. Kleber,Stacey Knight,Stacey Knight,José Eduardo Krieger,Michiaki Kubo,Lenore J. Launer,Jari Laurikka,Terho Lehtimäki,Kirsten Leineweber,Rozenn N. Lemaitre,Man Li,Man Li,Hong Euy Lim,Henry J. Lin,Honghuang Lin,Honghuang Lin,Lars Lind,Cecilia M. Lindgren,Marja-Liisa Lokki,Barry London,Ruth J. F. Loos,Siew-Kee Low,Yingchang Lu,Leo-Pekka Lyytikäinen,Peter W. Macfarlane,Patrik K. E. Magnusson,Anubha Mahajan,Rainer Malik,Alfredo José Mansur,Gregory M. Marcus,Lauren Margolin,Kenneth B. Margulies,Winfried März,Winfried März,David D. McManus,Olle Melander,Sanghamitra Mohanty,Jay A. Montgomery,Michael Morley,Andrew P. Morris,Martina Müller-Nurasyid,Andrea Natale,Saman Nazarian,Benjamin Neumann,Christopher Newton-Cheh,Christopher Newton-Cheh,Maartje N. Niemeijer,Kjell Nikus,Peter M. Nilsson,Raymond Noordam,Heidi Oellers,Morten S. Olesen,Marju Orho-Melander,Sandosh Padmanabhan,Hui Nam Pak,Guillaume Paré,Guillaume Paré,Nancy L. Pedersen,Joanna Pera,Alexandre C. Pereira,David J. Porteous,Bruce M. Psaty,Bruce M. Psaty,Sara L. Pulit,Sara L. Pulit,Sara L. Pulit,Clive R. Pullinger,Daniel J. Rader,Lena Refsgaard,Marta Ribasés,Marta Ribasés,Paul M. Ridker,Michiel Rienstra,Lorenz Risch,Dan M. Roden,Jonathan Rosand,Jonathan Rosand,Michael A. Rosenberg,Michael A. Rosenberg,Natalia S. Rost,Natalia S. Rost,Jerome I. Rotter,Samir Saba,Roopinder K. Sandhu,Renate B. Schnabel,Katharina Schramm,Heribert Schunkert,Claudia Schurman,Stuart A. Scott,Ilkka Seppälä,Christian M. Shaffer,Svati H. Shah,Alaa Shalaby,Alaa Shalaby,Jaemin Shim,M. Benjamin Shoemaker,Joylene E. Siland,Juha Sinisalo,Moritz F. Sinner,Agnieszka Slowik,Albert V. Smith,Blair H. Smith,J. Gustav Smith,J. Gustav Smith,Jonathan D. Smith,Nicholas L. Smith,Nicholas L. Smith,Elsayed Z. Soliman,Nona Sotoodehnia,Bruno H. Stricker,Albert Y. Sun,Han Sun,Jesper Hastrup Svendsen,Toshihiro Tanaka,Kahraman Tanriverdi,Kent D. Taylor,Maris Teder-Laving,Alexander Teumer,Sébastien Thériault,Sébastien Thériault,Stella Trompet,Nathan R. Tucker,Nathan R. Tucker,Arnljot Tveit,Arnljot Tveit,André G. Uitterlinden,Pim van der Harst,Isabelle C. Van Gelder,David R. Van Wagoner,Niek Verweij,Efthymia Vlachopoulou,Uwe Völker,Biqi Wang,Peter Weeke,Peter Weeke,Bob Weijs,Raul Weiss,Stefan Weiss,Quinn S. Wells,Kerri L. Wiggins,Jorge A. Wong,Daniel Woo,Bradford B. Worrall,Pil Sung Yang,Jie Yao,Zachary T. Yoneda,Tanja Zeller,Lingyao Zeng,Steven A. Lubitz,Steven A. Lubitz,Kathryn L. Lunetta,Kathryn L. Lunetta,Patrick T. Ellinor,Patrick T. Ellinor +260 more
TL;DR: This large, multi-ethnic genome-wide association study identifies 97 loci significantly associated with atrial fibrillation that are enriched for genes involved in cardiac development, electrophysiology, structure and contractile function.
Journal ArticleDOI
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Padhraig Gormley,Verneri Anttila,Verneri Anttila,Bendik S. Winsvold,Bendik S. Winsvold,Priit Palta,Tõnu Esko,Tõnu Esko,Tõnu Esko,Tune H. Pers,Kai-How Farh,Kai-How Farh,Kai-How Farh,Ester Cuenca-León,Mikko Muona,Nicholas A. Furlotte,Tobias Kurth,Tobias Kurth,Andres Ingason,George McMahon,Lannie Ligthart,Gisela M. Terwindt,Mikko Kallela,Tobias Freilinger,Tobias Freilinger,Caroline Ran,Scott G. Gordon,Anine H. Stam,Stacy Steinberg,Guntram Borck,Markku Koiranen,Lydia Quaye,Hieab H.H. Adams,Terho Lehtimäki,Antti-Pekka Sarin,Juho Wedenoja,David A. Hinds,Julie E. Buring,Julie E. Buring,Markus Schürks,Paul M. Ridker,Paul M. Ridker,Maria Gudlaug Hrafnsdottir,Hreinn Stefansson,Susan M. Ring,Jouke-Jan Hottenga,Brenda W.J.H. Penninx,Markus Färkkilä,Ville Artto,Mari A. Kaunisto,Salli Vepsäläinen,Rainer Malik,Andrew C. Heath,Pamela A. F. Madden,Nicholas G. Martin,Grant W. Montgomery,Mitja I. Kurki,Mart Kals,Reedik Mägi,Kalle Pärn,Eija Hamalainen,Hailiang Huang,Hailiang Huang,Andrea Byrnes,Andrea Byrnes,Lude Franke,Jie Huang,Evie Stergiakouli,Phil Lee,Phil Lee,Cynthia Sandor,Caleb Webber,Zameel M. Cader,Zameel M. Cader,Bertram Müller-Myhsok,Stefan Schreiber,Thomas Meitinger,Johan G. Eriksson,Johan G. Eriksson,Veikko Salomaa,Kauko Heikkilä,Elizabeth Loehrer,Elizabeth Loehrer,André G. Uitterlinden,Albert Hofman,Cornelia M. van Duijn,Lynn Cherkas,Linda M. Pedersen,Audun Stubhaug,Audun Stubhaug,Christopher Sivert Nielsen,Christopher Sivert Nielsen,Minna Männikkö,Evelin Mihailov,Lili Milani,Hartmut Göbel,Ann-Louise Esserlind,Anne Francke Christensen,Thomas Hansen,Thomas Werge,Thomas Werge,Thomas Werge,Jaakko Kaprio,Jaakko Kaprio,Arpo Aromaa,Olli T. Raitakari,Olli T. Raitakari,M. Arfan Ikram,Tim D. Spector,Marjo-Riitta Järvelin,Andres Metspalu,Christian Kubisch,David P. Strachan,Michel D. Ferrari,Andrea Carmine Belin,Martin Dichgans,Maija Wessman,Arn M. J. M. van den Maagdenberg,John-Anker Zwart,John-Anker Zwart,Dorret I. Boomsma,George Davey Smith,Kari Stefansson,Kari Stefansson,Nicholas Eriksson,Mark J. Daly,Mark J. Daly,Benjamin M. Neale,Benjamin M. Neale,Jes Olesen,Daniel I. Chasman,Daniel I. Chasman,Dale R. Nyholt,Aarno Palotie +133 more
TL;DR: For example, the authors identified 44 independent single-nucleotide polymorphisms (SNPs) significantly associated with migraine risk (P < 5 × 10−8) that mapped to 38 distinct genomic loci, including 28 loci not previously reported and a locus that to date is the first to be identified on chromosome X.