D
Daniel I. Chasman
Researcher at Brigham and Women's Hospital
Publications - 534
Citations - 85313
Daniel I. Chasman is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 134, co-authored 484 publications receiving 72180 citations. Previous affiliations of Daniel I. Chasman include Washington University in St. Louis & Glenfield Hospital.
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Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six Countries
Amber N Wilcox,Parichoy Pal Choudhury,Chi Gao,Anika Hüsing,Mikael Eriksson,Min Shi,Christopher J. Scott,Brian D. Carter,Kara Martin,Elaine F. Harkness,Elaine F. Harkness,Mark N. Brook,Thomas U. Ahearn,Nasim Mavaddat,Antonis C. Antoniou,Jenny Chang-Claude,Jenny Chang-Claude,Jacques Simard,Michael Jones,Nick Orr,Minouk J. Schoemaker,Anthony J. Swerdlow,Sarah Sampson,William G. Newman,Elke M van Veen,D. Gareth Evans,Robert J. MacInnis,Robert J. MacInnis,Graham G. Giles,Graham G. Giles,Graham G. Giles,Melissa C. Southey,Melissa C. Southey,Melissa C. Southey,Roger L. Milne,Roger L. Milne,Roger L. Milne,Susan M. Gapstur,Mia M. Gaudet,Stacey J. Winham,Kathy Brandt,Aaron D. Norman,Celine M. Vachon,Dale P. Sandler,Clarice R. Weinberg,Kamila Czene,Marike Gabrielson,Per Hall,Carla H. van Gils,Kay-Tee Khaw,Myrto Barrdahl,Rudolf Kaaks,Paul M. Ridker,Paul M. Ridker,Julie E. Buring,Julie E. Buring,Daniel I. Chasman,Daniel I. Chasman,Douglas F. Easton,Marjanka K. Schmidt,Peter Kraft,Montserrat Garcia-Closas,Nilanjan Chatterjee +62 more
TL;DR: Evaluation across multiple prospective cohorts demonstrates that integrating a 313-SNP PRS into a risk model substantially improves its ability to stratify women of European ancestry for applying current breast cancer prevention guidelines.
Journal ArticleDOI
Gene-gene Interaction Analyses for Atrial Fibrillation
Honghuang Lin,Honghuang Lin,Martina Mueller-Nurasyid,Albert V. Smith,Dan E. Arking,John Barnard,Traci M. Bartz,Kathryn L. Lunetta,Kathryn L. Lunetta,Kurt Lohman,Marcus E. Kleber,Steven A. Lubitz,Bastiaan Geelhoed,Stella Trompet,Maartje N. Niemeijer,Tim Kacprowski,Daniel I. Chasman,Derek Klarin,Derek Klarin,Moritz F. Sinner,Melanie Waldenberger,Thomas Meitinger,Tamara B. Harris,Lenore J. Launer,Elsayed Z. Soliman,Lin Y. Chen,Jonathan D. Smith,David R. Van Wagoner,Jerome I. Rotter,Bruce M. Psaty,Bruce M. Psaty,Zhijun Xie,Audrey E. Hendricks,Audrey E. Hendricks,Jingzhong Ding,Graciela E. Delgado,Niek Verweij,Pim van der Harst,Peter W. Macfarlane,Ian Ford,Albert Hofman,André G. Uitterlinden,Jan Heeringa,Oscar H. Franco,Jan A. Kors,Stefan Weiss,Henry Völzke,Lynda M. Rose,Pradeep Natarajan,Pradeep Natarajan,Sekar Kathiresan,Sekar Kathiresan,Stefan Kääb,Vilmundur Gudnason,Alvaro Alonso,Mina K. Chung,Susan R. Heckbert,Susan R. Heckbert,Emelia J. Benjamin,Emelia J. Benjamin,Yongmei Liu,Winfried März,Winfried März,Winfried März,Michiel Rienstra,J. Wouter Jukema,Bruno H. Stricker,Marcus Dörr,Christine M. Albert,Patrick T. Ellinor +69 more
TL;DR: A large-scale association analysis of gene-gene interactions with AF performed in 8,173 AF cases and 65,237 AF-free referents collected from 15 studies for discovery did not find significant interactions that were associated with AF susceptibility.
Posted ContentDOI
A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians
Heejung Shim,Daniel I. Chasman,Joshua D. Smith,Samia Mora,Paul M. Ridker,Deborah A. Nickerson,Ronald M. Krauss,Matthew Stephens +7 more
TL;DR: This study provides a more detailed picture of association with the entire IDL/LDL subfraction profile than any prior genetic association studies of either lipid-related measures or their response to statin treatment, and demonstrates that joint analyses of related measurements can considerably increase power to detect associations compared with conventional univariate analyses.
Journal ArticleDOI
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Valérie Turcot,Yingchang Lu,Yingchang Lu,Heather M. Highland,Heather M. Highland,Claudia Schurmann,Anne E. Justice,Rebecca S. Fine,Rebecca S. Fine,Rebecca S. Fine,Jonathan P. Bradfield,Tõnu Esko,Tõnu Esko,Tõnu Esko,Ayush Giri,Mariaelisa Graff,Xiuqing Guo,Audrey E. Hendricks,Audrey E. Hendricks,Tugce Karaderi,Tugce Karaderi,Adelheid Lempradl,Adam E. Locke,Adam E. Locke,Anubha Mahajan,Eirini Marouli,Suthesh Sivapalaratnam,Suthesh Sivapalaratnam,Kristin L. Young,Tamuno Alfred,Mary F. Feitosa,Nicholas G. D. Masca,Nicholas G. D. Masca,Alisa K. Manning,Carolina Medina-Gomez,Poorva Mudgal,Maggie C.Y. Ng,Alexander P. Reiner,Alexander P. Reiner,Sailaja Vedantam,Sailaja Vedantam,Sailaja Vedantam,Sara M. Willems,Thomas W. Winkler,Gonçalo R. Abecasis,Katja K.H. Aben,Dewan S. Alam,Sameer E. Al-Harthi,Sameer E. Al-Harthi,Matthew A. Allison,Philippe Amouyel,Philippe Amouyel,Philippe Amouyel,Folkert W. Asselbergs,Folkert W. Asselbergs,Paul L. Auer,Beverley Balkau,Lia E. Bang,Inês Barroso,Inês Barroso,Inês Barroso,Lisa Bastarache,Marianne Benn,Marianne Benn,Sven Bergmann,Sven Bergmann,Lawrence F. Bielak,Matthias Blüher,Michael Boehnke,Heiner Boeing,Eric Boerwinkle,Eric Boerwinkle,Carsten A. Böger,Jette Bork-Jensen,Michiel L. Bots,Erwin P. Bottinger,Donald W. Bowden,Ivan Brandslund,Gerome Breen,Gerome Breen,Murray H. Brilliant,Linda Broer,Marco Brumat,Amber A. Burt,Adam S. Butterworth,Peter T. Campbell,Stefania Cappellani,David J. Carey,Eulalia Catamo,Mark J. Caulfield,John C. Chambers,John C. Chambers,John C. Chambers,Daniel I. Chasman,Yii-Der Ida Chen,Rajiv Chowdhury,Cramer Christensen,Audrey Y. Chu,Audrey Y. Chu,Massimiliano Cocca,Francis S. Collins,James P. Cook,Janie Corley,Jordi Corominas Galbany,Amanda J. Cox,Amanda J. Cox,David S. Crosslin,Gabriel Cuellar-Partida,Gabriel Cuellar-Partida,Angela D'Eustacchio,John Danesh,Gail Davies,Gail Davies,Paul I. W. de Bakker,Mark C. H. Groot,Renée de Mutsert,Ian J. Deary,Ian J. Deary,George Dedoussis,Ellen W. Demerath,Martin den Heijer,Anneke I den Hollander,Hester M. den Ruijter,Joe Dennis,Josh C. Denny,Emanuele Di Angelantonio,Fotios Drenos,Fotios Drenos,Mengmeng Du,Mengmeng Du,Marie-Pierre Dubé,Marie-Pierre Dubé,Alison M. Dunning,Douglas F. Easton,Todd L. Edwards,David Ellinghaus,Patrick T. Ellinor,Patrick T. Ellinor,Paul Elliott,Evangelos Evangelou,Evangelos Evangelou,Aliki-Eleni Farmaki,Aliki-Eleni Farmaki,I. Sadaf Farooqi,I. Sadaf Farooqi,Jessica D. Faul,Sascha Fauser,Shuang Feng,Ele Ferrannini,Jean Ferrières,Jose C. Florez,Ian Ford,Myriam Fornage,Oscar H. Franco,Andre Franke,Paul W. Franks,Paul W. Franks,Paul W. Franks,Nele Friedrich,Ruth Frikke-Schmidt,Ruth Frikke-Schmidt,Tessel E. Galesloot,Wei Gan,Ilaria Gandin,Paolo Gasparini,Jane Gibson,Vilmantas Giedraitis,Anette P. Gjesing,Penny Gordon-Larsen,Mathias Gorski,Mathias Gorski,Hans-Jörgen Grabe,Hans-Jörgen Grabe,Struan F.A. Grant,Struan F.A. Grant,Niels Grarup,Helen Griffiths,Megan L. Grove,Vilmundur Gudnason,Stefan Gustafsson,Jeffrey Haessler,Hakon Hakonarson,Hakon Hakonarson,Anke R. Hammerschlag,Torben Hansen,Kathleen Mullan Harris,Tamara B. Harris,Andrew T. Hattersley,Christian Theil Have,Caroline Hayward,Liang He,Liang He,Nancy L. Heard-Costa,Nancy L. Heard-Costa,Andrew C. Heath,Iris M. Heid,Øyvind Helgeland,Øyvind Helgeland,Jussi Hernesniemi,Alex W. Hewitt,Alex W. Hewitt,Alex W. Hewitt,Oddgeir L. Holmen,G. Kees Hovingh,Joanna M. M. Howson,Yao Hu,Paul L. Huang,Jennifer E. Huffman,M. Arfan Ikram,Erik Ingelsson,Erik Ingelsson,Anne U. Jackson,Jan-Håkan Jansson,Gail P. Jarvik,Gorm B. Jensen,Yucheng Jia,Stefan Johansson,Stefan Johansson,Marit E. Jørgensen,Marit E. Jørgensen,Torben Jørgensen,Torben Jørgensen,J. Wouter Jukema,Bratati Kahali,René S. Kahn,Mika Kähönen,Pia R. Kamstrup,Stavroula Kanoni,Jaakko Kaprio,Jaakko Kaprio,Maria Karaleftheri,Sharon L.R. Kardia,Fredrik Karpe,Sekar Kathiresan,Sekar Kathiresan,Frank Kee,Lambertus A. Kiemeney,Eric Kim,Hidetoshi Kitajima,Pirjo Komulainen,Jaspal S. Kooner,Charles Kooperberg,Tellervo Korhonen,Tellervo Korhonen,Tellervo Korhonen,Peter Kovacs,Helena Kuivaniemi,Helena Kuivaniemi,Zoltán Kutalik,Zoltán Kutalik,Kari Kuulasmaa,Johanna Kuusisto,Markku Laakso,Timo A. Lakka,David Lamparter,David Lamparter,Ethan M. Lange,Leslie A. Lange,Claudia Langenberg,Eric B. Larson,Eric B. Larson,Nanette R. Lee,Terho Lehtimäki,Cora E. Lewis,Huaixing Li,Jin Li,Ruifang Li-Gao,Honghuang Lin,Keng-Hung Lin,Li-An Lin,Xu Lin,Lars Lind,Jaana Lindström,Allan Linneberg,Ching-Ti Liu,Dajiang J. Liu,Yongmei Liu,Ken S. Lo,Artitaya Lophatananon,Andrew J. Lotery,Anu Loukola,Jian'an Luan,Steven A. Lubitz,Steven A. Lubitz,Leo-Pekka Lyytikäinen,Satu Männistö,Gaëlle Marenne,Angela L. Mazul,Mark I. McCarthy,Mark I. McCarthy,Roberta McKean-Cowdin,Sarah E. Medland,Karina Meidtner,Lili Milani,Vanisha Mistry,Vanisha Mistry,Paul Mitchell,Karen L. Mohlke,Leena Moilanen,Marie Moitry,Grant W. Montgomery,Grant W. Montgomery,Dennis O. Mook-Kanamori,Carmel Moore,Trevor A. Mori,Andrew D. Morris,Andrew P. Morris,Andrew P. Morris,Martina Müller-Nurasyid,Patricia B. Munroe,Mike A. Nalls,Narisu Narisu,Christopher P. Nelson,Christopher P. Nelson,Matt J. Neville,Sune F. Nielsen,Sune F. Nielsen,Kjell Nikus,Pål R. Njølstad,Pål R. Njølstad,Børge G. Nordestgaard,Børge G. Nordestgaard,Dale R. Nyholt,Dale R. Nyholt,Jeffrey R. O'Connel,Michelle L. O'Donoghue,Loes M. Olde Loohuis,Roel A. Ophoff,Roel A. Ophoff,Katharine R. Owen,Chris J. Packard,Sandosh Padmanabhan,Colin N. A. Palmer,Nicholette D. Palmer,Gerard Pasterkamp,Aniruddh P. Patel,Aniruddh P. Patel,Alison Pattie,Oluf Pedersen,Peggy L. Peissig,Gina M. Peloso,Craig E. Pennell,Markus Perola,James A. Perry,John R. B. Perry,Tune H. Pers,Tune H. Pers,Thomas N. Person,Annette Peters,Eva Rabing Brix Petersen,Patricia A. Peyser,Ailith Pirie,Ozren Polasek,Ozren Polasek,Tinca J. C. Polderman,Hannu Puolijoki,Olli T. Raitakari,Olli T. Raitakari,Asif Rasheed,Rainer Rauramaa,Dermot F. Reilly,Frida Renström,Frida Renström,Myriam Rheinberger,Paul M. Ridker,Paul M. Ridker,John D. Rioux,John D. Rioux,Manuel A. Rivas,Manuel A. Rivas,David J. Roberts,David J. Roberts,David J. Roberts,Neil R. Robertson,Neil R. Robertson,Antonietta Robino,Olov Rolandsson,Igor Rudan,Katherine S. Ruth,Danish Saleheen,Veikko Salomaa,Nilesh J. Samani,Nilesh J. Samani,Yadav Sapkota,Naveed Sattar,Robert E. Schoen,Pamela J. Schreiner,Matthias B. Schulze,Robert A. Scott,Marcelo P. Segura-Lepe,Svati H. Shah,Wayne Huey-Herng Sheu,Wayne Huey-Herng Sheu,Xueling Sim,Xueling Sim,Andrew J. Slater,Kerrin S. Small,Albert V. Smith,Lorraine Southam,Lorraine Southam,Tim D. Spector,Elizabeth K. Speliotes,John M. Starr,Kari Stefansson,Kari Stefansson,Valgerdur Steinthorsdottir,Kathleen Stirrups,Kathleen Stirrups,Konstantin Strauch,Heather M. Stringham,Michael Stumvoll,Liang Sun,Liang Sun,Praveen Surendran,Amy J. Swift,Hayato Tada,Hayato Tada,Katherine E. Tansey,Katherine E. Tansey,Jean-Claude Tardif,Kent D. Taylor,Alexander Teumer,Deborah J. Thompson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Betina H. Thuesen,Anke Tönjes,Gerard Tromp,Gerard Tromp,Stella Trompet,Emmanouil Tsafantakis,Jaakko Tuomilehto,Anne Tybjærg-Hansen,Anne Tybjærg-Hansen,Jonathan Tyrer,Rudolf Uher,André G. Uitterlinden,Matti Uusitupa,Sander W. van der Laan,Cornelia M. van Duijn,Nienke van Leeuwen,Nienke van Leeuwen,Jessica van Setten,Mauno Vanhala,Anette Varbo,Anette Varbo,Tibor V. Varga,Rohit Varma,Digna R. Velez Edwards,Sita H. Vermeulen,Giovanni Veronesi,Henrik Vestergaard,Henrik Vestergaard,Veronique Vitart,Thomas F. Vogt,Uwe Völker,Dragana Vuckovic,Lynne E. Wagenknecht,Mark Walker,Lars Wallentin,Feijie Wang,Carol A. Wang,Shuai Wang,Yiqin Wang,Erin B. Ware,Nicholas J. Wareham,Helen R. Warren,Dawn M. Waterworth,Jennifer Wessel,Harvey D. White,Cristen J. Willer,James G. Wilson,Daniel R. Witte,Andrew R. Wood,Ying Wu,Hanieh Yaghootkar,Jie Yao,Pang Yao,Laura M. Yerges-Armstrong,Laura M. Yerges-Armstrong,Robin Young,Robin Young,Eleftheria Zeggini,Xiaowei Zhan,Weihua Zhang,Weihua Zhang,Jing Hua Zhao,Wei Zhao,Wei Zhao,Wei Zhou,Krina T. Zondervan,Krina T. Zondervan,Jerome I. Rotter,John Andrew Pospisilik,Fernando Rivadeneira,Ingrid B. Borecki,Panos Deloukas,Panos Deloukas,Timothy M. Frayling,Guillaume Lettre,Guillaume Lettre,Kari E. North,Cecilia M. Lindgren,Cecilia M. Lindgren,Joel N. Hirschhorn,Ruth J. F. Loos +506 more
TL;DR: In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled and this error has now been corrected in the HTML and PDF versions of the article.
Directional dominance on stature and cognition in diverse human populations
Peter K. Joshi,Tõnu Esko,Hannele Mattsson,Niina Eklund,Ilaria Gandin,Teresa Nutile,Anne U. Jackson,Claudia Schurmann,Albert V. Smith,Weihua Zhang,Yukinori Okada,A. Stancáková,Jessica D. Faul,Wei Zhao,Traci M. Bartz,Maria Pina Concas,Nora Franceschini,Stefan Enroth,Veronique Vitart,Stella Trompet,Xiuqing Guo,Daniel I. Chasman,Jeffrey R. O'Connel,Tanguy Corre,Suraj S. Nongmaithem,Yuan-Tsong Chen,Massimo Mangino,Daniela Ruggiero,Michela Traglia,Aliki-Eleni Farmaki,Tim Kacprowski,Andrew Bjonnes,A. van deSpek,Ying Wu,Anil K. Giri,Lisa R. Yanek,Lihua Wang,Edith Hofer,Cornelius A. Rietveld,Olga McLeod,Marilyn C. Cornelis,Cristian Pattaro,Niek Verweij,Clemens Baumbach,Abdel Abdellaoui,Helen R. Warren,Dragana Vuckovic,Hao Mei,Claude Bouchard,John R. B. Perry,Stefania Cappellani,Saira Saeed Mirza,Miles C. Benton,Ulrich Broeckel,Sarah E. Medland,Penelope A. Lind,Giovanni Malerba,Alexander W. Drong,Loic Yengo,Lawrence F. Bielak,Degui Zhi,P.J. van deMost,Daniel Shriner,R Magi,Gibran Hemani,Tugce Karaderi,Zhaoming Wang,Tian Liu,Ilja Demuth,Jing Hua Zhao,Weihua Meng,Lazaros Lataniotis,S.W. Van Der Laan,Jonathan P. Bradfield,Andrew R. Wood,Amélie Bonnefond,Tarunveer S. Ahluwalia,Leanne M. Hall,Erika Salvi,Seyhan Yazar,Lisbeth Carstensen,H.G. deHaan,Mark Abney,Uzma Afzal,Allison,Najaf Amin,Folkert W. Asselbergs,S. J. L. Bakker,R. G. Barr,Sebastian E. Baumeister,Daniel J. Benjamin,Sven Bergmann,Eric Boerwinkle,Erwin P. Bottinger,Campbell A,Aravinda Chakravarti,Yingleong Chan,Stephen J. Chanock,Constance Chen,F. S. Collins,Jmc Connell,Adolfo Correa,L. A. Cupples,Gail Davies,Marcus Dörr,Georg Ehret,Steve Ellis,B. Feenstra,Mary F. Feitosa,Ian Ford,Caroline S. Fox,Timothy M. Frayling,Nele Friedrich,Frank Geller,Generation Scotland,Irina Gillham-Nasenya,Rebecca F. Gottesman,Misa Graff,Francine Grodstein,Charles Gu,Chris Haley,Christopher J Hammond,Sarah E. Harris,Tamara B. Harris,Nicholas D. Hastie,Nancy L. Heard-Costa,Kauko Heikkilä,Lynne J. Hocking,Georg Homuth,Jouke-Jan Hottenga,Jinyan Huang,Jennifer E. Huffman,Pirro G. Hysi,Ikram,Erik Ingelsson,Anni Joensuu,Åsa Johansson,P. Jousilahti,Joop Jukema,Mika Kähönen,Yoichiro Kamatani,Stavroula Kanoni,Shona M. Kerr,Nazir M. Khan,Koellinger,Heikki A. Koistinen,Manraj K. Kooner,Michiaki Kubo,Johanna Kuusisto,Jari Lahti,Lenore J. Launer,Rodney A. Lea,Benjamin Lehne,Terho Lehtimäki,D C Liewald,Lars Lind,Marie Loh,Marja-Liisa Lokki,Stephanie J. London,Stephanie J. Loomis,Anu Loukola,Yingchang Lu,Thomas Lumley,Annamari Lundqvist,Satu Männistö,P. Marques-Vidal,Corrado Masciullo,Angela Matchan,J. Mathias,Koichi Matsuda,James B. Meigs,Christa Meisinger,Thomas Meitinger,Cristina Menni,Frank D. Mentch,E. Mihailov,Lili Milani,May E Montasser,Grant W. Montgomery,Alanna C. Morrison,Richard H. Myers,Rajiv Nadukuru,Pau Navarro,M. Nalis,Nieminen,Ilja M. Nolte,George T. O'Connor,Adesola Ogunniyi,Sandosh Padmanabhan,Walter Palmas,James S. Pankow,Inga Patarčić,Francesca Pavani,Patricia A. Peyser,Kirsi H. Pietiläinen,Neil R Poulter,Inga Prokopenko,Sarju Ralhan,Paul Redmond,Stephen S. Rich,Harri Rissanen,Antonietta Robino,Ludger Rose,Richard J. Rose,Cinzia Sala,Babatunde L. Salako,Veikko Salomaa,Antti-Pekka Sarin,Richa Saxena,Reinhold Schmidt,Laura J. Scott,William R. Scott,Bengt Sennblad,Sudha Seshadri,Peter S. Sever,Smeeta Shrestha,Blair H. Smith,Jennifer A. Smith,Nicole Soranzo,N. Sotoodehnia,L. Southam,Alice Stanton,Maria G. Stathopoulou,Konstantin Strauch,Rona J. Strawbridge,Matthew Suderman,Nikhil Tandon,Sandra Tang,Kent D. Taylor,Bamidele O. Tayo,Anna Maria Töglhofer,Maciej Tomaszewski,Natalia Tšernikova,Jaakko Tuomilehto,André G. Uitterlinden,Dhananjay Vaidya,A. vanHylckama Vlieg,J. vanSetten,Tuija Vasankari,S. Vedantam,Efthymia Vlachopoulou,Diego Vozzi,Eero Vuoksimaa,M. Waldenberger,Erin B. Ware,William Wentworth-Shields,John Whitfield,Sarah H. Wild,Gonneke Willemsen,C. S. Yajnik,Jie Yao,Gianluigi Zaza,Xiaofeng Zhu,Rany M. Salem,Mads Melbye,Hans Bisgaard,Nilesh J. Samani,D. Cusi,David A. Mackey,Richard S. Cooper,Philippe Froguel,Gerard Pasterkamp,Struan F.A. Grant,Hakon Hakonarson,Luigi Ferrucci,Robert A. Scott,Andrew D. Morris,Colin N. A. Palmer,George Dedoussis,Panagiotis Deloukas,Lars Bertram,Ulman Lindenberger,Sonja I. Berndt,Cecilia M. Lindgren,Nicholas J. Timpson,A Tönjes,Patricia B. Munroe,T. I. A. Sørensen,Charles N. Rotimi,Donna K. Arnett,Albertine J. Oldehinkel,Sharon L.R. Kardia,B. Balkau,Giovanni Gambaro,Andrew P. Morris,Johan G. Eriksson,Margaret J. Wright,Nicholas G. Martin,Steven C. Hunt,John M. Starr,Ian J. Deary,Lyn R. Griffiths,Henning Tiemeier,Nicola Pirastu,Jaakko Kaprio,Nicholas J. Wareham,Louis Pérusse,James G. Wilson,S. Girotto,Mark J. Caulfield,Olli T. Raitakari,Dorret I. Boomsma,Christian Gieger,P. van der Harst,Andrew A. Hicks,Peter Kraft,Juha Sinisalo,Paul Knekt,Magnus Johannesson,Patrik K. E. Magnusson,Anders Hamsten,Ingrid B. Borecki,Erkki Vartiainen,Diane M. Becker,Dwaipayan Bharadwaj,Karen L. Mohlke,Michael Boehnke,C.M. vanDuijn,Dharambir K. Sanghera,Alexander Teumer,Eleftheria Zeggini,Andres Metspalu,Paolo Gasparini,S. Ulivi,Carole Ober,Daniela Toniolo,Igor Rudan,David J. Porteous,Marina Ciullo,Tim D. Spector,Caroline Hayward,Josée Dupuis,Ruth J. F. Loos,Alan F. Wright,Giriraj R. Chandak,Peter Vollenweider,Alan R. Shuldiner,Paul M. Ridker,Jerome I. Rotter,Naveed Sattar,Ulf Gyllensten,Kari E. North,Mario Pirastu,Bruce M. Psaty,David R. Weir,Mauri Laakso,Vilmundur Gudnason,Atsushi Takahashi,John C. Chambers,Jaspal S. Kooner,David P. Strachan,Harry Campbell,Joel N. Hirschhorn,Markus Perola,Ozren Polasek,J.F. Wilson +355 more
TL;DR: In this paper, the authors use runs of homozygosity to study 16 health-related quantitative traits in 354,224 individuals from 102 cohorts, and find statistically significant associations between summed runs and four complex traits: height, forced expiratory lung volume in one second, general cognitive ability and educational attainment.