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David B. Weir
Researcher at Columbia University
Publications - 4
Citations - 5094
David B. Weir is an academic researcher from Columbia University. The author has contributed to research in topics: microRNA & Gene expression profiling. The author has an hindex of 4, co-authored 4 publications receiving 4847 citations.
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Journal ArticleDOI
A mammalian microRNA expression atlas based on small RNA library sequencing.
Pablo Landgraf,Mirabela Rusu,Robert L. Sheridan,Alain Sewer,Alain Sewer,Nicola Iovino,Alexei A. Aravin,Sébastien Pfeffer,Amanda J. Rice,Alice O. Kamphorst,Markus Landthaler,Carolina Lin,Nicholas D. Socci,Leandro C. Hermida,Valerio Fulci,Sabina Chiaretti,Robin Foà,Julia Schliwka,Uta Fuchs,Astrid Novosel,Roman-Ulrich Müller,Roman-Ulrich Müller,Bernhard Schermer,Ute Bissels,Jason M. Inman,Quang Phan,Minchen Chien,David B. Weir,Ruchi Choksi,Gabriella De Vita,Daniela Frezzetti,Hans Ingo Trompeter,Veit Hornung,Grace Teng,Gunther Hartmann,Miklós Palkovits,Roberto Di Lauro,Peter Wernet,Giuseppe Macino,Charles E. Rogler,James W. Nagle,Jingyue Ju,F. Nina Papavasiliou,Thomas Benzing,Peter Lichter,Wayne Tam,Michael J. Brownstein,Andreas Bosio,Arndt Borkhardt,James J. Russo,Chris Sander,Mihaela Zavolan,Mihaela Zavolan,Thomas Tuschl +53 more
TL;DR: A relatively small set of miRNAs, many of which are ubiquitously expressed, account for most of the differences in miRNA profiles between cell lineages and tissues.
Journal ArticleDOI
Cellular cofactors affecting hepatitis C virus infection and replication
Glenn Randall,Maryline Panis,Jacob D. Cooper,Timothy L. Tellinghuisen,Karen E. Sukhodolets,Sébastien Pfeffer,Markus Landthaler,Pablo Landgraf,Sherry Kan,Brett D. Lindenbach,Minchen Chien,David B. Weir,James J. Russo,Jingyue Ju,Michael J. Brownstein,Robert L. Sheridan,Chris Sander,Mihaela Zavolan,Thomas Tuschl,Charles M. Rice +19 more
TL;DR: The data define 26 host genes that modulate HCV infection and indicate that the requirement for functional RNAi for HCV replication is dominant over any antiviral activity this pathway may exert against HCV.
Journal ArticleDOI
Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia.
Valerio Fulci,Sabina Chiaretti,Marina Goldoni,Gianluca Azzalin,Nicoletta Carucci,Simona Tavolaro,Leandro Castellano,Armando Magrelli,Franca Citarella,Monica Messina,Roberta Maggio,Nadia Peragine,Simona Santangelo,Francesca Romana Mauro,Pablo Landgraf,Thomas Tuschl,David B. Weir,Minchen Chien,James J. Russo,Jingyue Ju,Robert L. Sheridan,Chris Sander,Mihaela Zavolan,Anna Guarini,Robin Foà,Giuseppe Macino +25 more
TL;DR: The results of this study offer for the first time a comprehensive and quantitative profile of miRNA expression in CLL and their healthy counterpart, suggesting that miRNAs could play a primary role in the disease itself.
Journal ArticleDOI
Prognostic Values of microRNAs in Colorectal Cancer
Yaguang Xi,Andrea Formentini,Minchen Chien,David B. Weir,James J. Russo,Jingyue Ju,Marko Kornmann,Jingfang Ju +7 more
TL;DR: Hsa-miR-200c may be a potential novel prognostic factor in colorectal cancer patients because of its strongly associated with the mutation status of the p53 tumor suppressor gene.