U
Ute Bissels
Researcher at Miltenyi Biotec
Publications - 18
Citations - 4611
Ute Bissels is an academic researcher from Miltenyi Biotec. The author has contributed to research in topics: Progenitor cell & Haematopoiesis. The author has an hindex of 10, co-authored 18 publications receiving 4308 citations.
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Journal ArticleDOI
A mammalian microRNA expression atlas based on small RNA library sequencing.
Pablo Landgraf,Mirabela Rusu,Robert L. Sheridan,Alain Sewer,Alain Sewer,Nicola Iovino,Alexei A. Aravin,Sébastien Pfeffer,Amanda J. Rice,Alice O. Kamphorst,Markus Landthaler,Carolina Lin,Nicholas D. Socci,Leandro C. Hermida,Valerio Fulci,Sabina Chiaretti,Robin Foà,Julia Schliwka,Uta Fuchs,Astrid Novosel,Roman-Ulrich Müller,Roman-Ulrich Müller,Bernhard Schermer,Ute Bissels,Jason M. Inman,Quang Phan,Minchen Chien,David B. Weir,Ruchi Choksi,Gabriella De Vita,Daniela Frezzetti,Hans Ingo Trompeter,Veit Hornung,Grace Teng,Gunther Hartmann,Miklós Palkovits,Roberto Di Lauro,Peter Wernet,Giuseppe Macino,Charles E. Rogler,James W. Nagle,Jingyue Ju,F. Nina Papavasiliou,Thomas Benzing,Peter Lichter,Wayne Tam,Michael J. Brownstein,Andreas Bosio,Arndt Borkhardt,James J. Russo,Chris Sander,Mihaela Zavolan,Mihaela Zavolan,Thomas Tuschl +53 more
TL;DR: A relatively small set of miRNAs, many of which are ubiquitously expressed, account for most of the differences in miRNA profiles between cell lineages and tissues.
Journal ArticleDOI
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes
Anna-Barbara Stittrich,Claudia Haftmann,Evridiki Sgouroudis,Anja A. Kühl,Ahmed N. Hegazy,Isabel Panse,René Riedel,Michael Flossdorf,Jun Dong,Franziska Fuhrmann,Gitta Anne Heinz,Zhuo Fang,Na Li,Ute Bissels,Farahnaz Hatam,Angelina Jahn,Ben Hammoud,Mareen Matz,Felix Michael Schulze,Ria Baumgrass,Andreas Bosio,Hans-Joachim Mollenkopf,Joachim R. Grün,Andreas Thiel,Wei Chen,Thomas Höfer,Christoph Loddenkemper,Max Löhning,Hyun-Dong Chang,Nikolaus Rajewsky,Andreas Radbruch,Mir-Farzin Mashreghi +31 more
TL;DR: A central role for miR-182 is demonstrated in the physiological regulation of IL-2-driven helper T cell–mediated immune responses and new therapeutic possibilities are opened.
Journal ArticleDOI
Absolute quantification of microRNAs by using a universal reference
Ute Bissels,Stefan Wild,Stefan Tomiuk,Angela Holste,Markus Hafner,Thomas Tuschl,Andreas Bosio +6 more
TL;DR: This work quantified miRNA copy numbers in liver samples and CD34(+)/CD133(-) hematopoietic progenitor cells and demonstrates the accuracy of the method by various spike-in experiments.
Journal ArticleDOI
MicroRNAs are shaping the hematopoietic landscape
TL;DR: This review summarizes the current knowledge about miRNA expression in hematopoietic stem and progenitor cells, and their role in the hematoietIC stem cell niche.
Journal ArticleDOI
Combined Characterization of microRNA and mRNA Profiles Delineates Early Differentiation Pathways of CD133+ and CD34+ Hematopoietic Stem and Progenitor Cells
Ute Bissels,Stefan Wild,Stefan Tomiuk,Markus Hafner,Hartmut Scheel,Aleksandra Mihailovic,Yeong-Hoon Choi,Thomas Tuschl,Andreas Bosio +8 more
TL;DR: The miRNAs expressed differentially between the CD133+ and CD34+CD133− cells are involved in inhibition of differentiation, prevention of apoptosis, and cytoskeletal remodeling.