D
David C. Rinker
Researcher at Vanderbilt University
Publications - 40
Citations - 1878
David C. Rinker is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Biology & Anopheles gambiae. The author has an hindex of 15, co-authored 29 publications receiving 1536 citations. Previous affiliations of David C. Rinker include Vanderbilt University Medical Center.
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Journal ArticleDOI
Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes
Daniel E. Neafsey,Robert M. Waterhouse,Mohammad Reza Abai,Sergey Aganezov,Max A. Alekseyev,James E. Allen,James Amon,Bruno Arcà,Peter Arensburger,Gleb N. Artemov,Lauren A. Assour,Hamidreza Basseri,Aaron M. Berlin,Bruce W. Birren,Stéphanie Blandin,Stéphanie Blandin,Andrew I. Brockman,Thomas R. Burkot,Austin Burt,Clara S. Chan,Cedric Chauve,Joanna C. Chiu,Mikkel B. Christensen,Carlo Costantini,Victoria L.M. Davidson,Elena Deligianni,Tania Dottorini,Vicky Dritsou,Stacey Gabriel,Wamdaogo M. Guelbeogo,Andrew Brantley Hall,Mira V. Han,Thaung Hlaing,Daniel S.T. Hughes,Daniel S.T. Hughes,Adam M. Jenkins,Xiaofang Jiang,Irwin Jungreis,Evdoxia G. Kakani,Evdoxia G. Kakani,Maryam Kamali,Petri Kemppainen,Ryan C. Kennedy,Ioannis K. Kirmitzoglou,Ioannis K. Kirmitzoglou,Lizette L. Koekemoer,Njoroge Laban,Nicholas Langridge,Mara K. N. Lawniczak,Manolis Lirakis,Neil F. Lobo,Ernesto Lowy,Robert M. MacCallum,Chunhong Mao,Gareth Maslen,Charles Mbogo,Jenny McCarthy,Kristin Michel,Sara N. Mitchell,Wendy Moore,Katherine A. Murphy,Anastasia N. Naumenko,Tony Nolan,Eva Maria Novoa,Samantha M. O’Loughlin,Chioma Oringanje,Mohammad Ali Oshaghi,Nazzy Pakpour,Philippos Aris Papathanos,Philippos Aris Papathanos,Ashley Peery,Michael Povelones,Anil Prakash,David P. Price,Ashok Rajaraman,Lisa J. Reimer,David C. Rinker,Antonis Rokas,Tanya L. Russell,N’Fale Sagnon,Maria V. Sharakhova,Terrance Shea,Felipe A. Simão,Felipe A. Simão,Frédéric Simard,Michel A. Slotman,Pradya Somboon,V. N. Stegniy,Claudio J. Struchiner,Claudio J. Struchiner,Gregg W.C. Thomas,Marta Tojo,Pantelis Topalis,Jose M. C. Tubio,Maria F. Unger,John Vontas,Catherine Walton,Craig S. Wilding,Judith H. Willis,Yi-Chieh Wu,Yi-Chieh Wu,Guiyun Yan,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Xiaofan Zhou,Flaminia Catteruccia,Flaminia Catteruccia,George K. Christophides,Frank H. Collins,Robert S. Cornman,Andrea Crisanti,Andrea Crisanti,Martin J. Donnelly,Martin J. Donnelly,Scott J. Emrich,Michael C. Fontaine,Michael C. Fontaine,William M. Gelbart,Matthew W. Hahn,Immo A. Hansen,Paul I. Howell,Fotis C. Kafatos,Manolis Kellis,Daniel Lawson,Christos Louis,Shirley Luckhart,Marc A. T. Muskavitch,Marc A. T. Muskavitch,José M. C. Ribeiro,Michael A. Riehle,Igor V. Sharakhov,Zhijian Tu,Laurence J. Zwiebel,Nora J. Besansky +133 more
TL;DR: The authors investigated the genomic basis of vectorial capacity and explore new avenues for vector control, sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution Comparative analyses show faster rates of gene gain and loss, elevated gene shuffling on the X chromosome, and more intron losses, relative to Drosophila.
Journal ArticleDOI
Functional agonism of insect odorant receptor ion channels
TL;DR: The identification and characterization of an Orco family agonist, VUAA1, is reported, which represents a powerful new family of compounds that can be used to disrupt the destructive behaviors of nuisance insects, agricultural pests, and disease vectors alike.
Journal ArticleDOI
Transcriptome profiling of chemosensory appendages in the malaria vector Anopheles gambiae reveals tissue- and sex-specific signatures of odor coding
TL;DR: The use of RNA-seq is demonstrated to characterize the sensory specializations of an important disease vector and grounded future studies investigating chemosensory processes, suggesting that the chemoreceptive spectrum, as defined by gene expression profiles, is largely similar in female and male An.
Journal ArticleDOI
Blood meal-induced changes to antennal transcriptome profiles reveal shifts in odor sensitivities in Anopheles gambiae
David C. Rinker,R. Jason Pitts,Xiaofan Zhou,Eunho Suh,Antonis Rokas,Antonis Rokas,Laurence J. Zwiebel,Laurence J. Zwiebel +7 more
TL;DR: It is posit that modest, yet cumulative, alterations of AgOr transcript levels modulate peripheral odor coding resulting in biologically relevant behavioral effects, and this results demonstrate that highly quantitative, RNAseq transcript abundance data can be successfully integrated with functional data to generate testable hypotheses.
Journal ArticleDOI
The evolutionary imprint of domestication on genome variation and function of the filamentous fungus Aspergillus oryzae.
John G. Gibbons,Leonidas Salichos,Jason C. Slot,David C. Rinker,Kriston L. McGary,Jonas G. King,Maren A. Klich,David L. Tabb,W. Hayes McDonald,Antonis Rokas +9 more
TL;DR: This work systematically examined genome-wide sequence and functional variation between the domesticated fungus Aspergillus oryzae and its wild relative A. flavus, suggesting that whereas animal and plant domestication was largely driven by Neolithic "genetic tinkering" of developmental pathways, microbe domesticated was driven by extensive remodeling of metabolism.