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David C. Rinker

Researcher at Vanderbilt University

Publications -  40
Citations -  1878

David C. Rinker is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Biology & Anopheles gambiae. The author has an hindex of 15, co-authored 29 publications receiving 1536 citations. Previous affiliations of David C. Rinker include Vanderbilt University Medical Center.

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Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes

Daniel E. Neafsey, +133 more
- 02 Jan 2015 - 
TL;DR: The authors investigated the genomic basis of vectorial capacity and explore new avenues for vector control, sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution Comparative analyses show faster rates of gene gain and loss, elevated gene shuffling on the X chromosome, and more intron losses, relative to Drosophila.
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Functional agonism of insect odorant receptor ion channels

TL;DR: The identification and characterization of an Orco family agonist, VUAA1, is reported, which represents a powerful new family of compounds that can be used to disrupt the destructive behaviors of nuisance insects, agricultural pests, and disease vectors alike.
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Transcriptome profiling of chemosensory appendages in the malaria vector Anopheles gambiae reveals tissue- and sex-specific signatures of odor coding

TL;DR: The use of RNA-seq is demonstrated to characterize the sensory specializations of an important disease vector and grounded future studies investigating chemosensory processes, suggesting that the chemoreceptive spectrum, as defined by gene expression profiles, is largely similar in female and male An.
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Blood meal-induced changes to antennal transcriptome profiles reveal shifts in odor sensitivities in Anopheles gambiae

TL;DR: It is posit that modest, yet cumulative, alterations of AgOr transcript levels modulate peripheral odor coding resulting in biologically relevant behavioral effects, and this results demonstrate that highly quantitative, RNAseq transcript abundance data can be successfully integrated with functional data to generate testable hypotheses.
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The evolutionary imprint of domestication on genome variation and function of the filamentous fungus Aspergillus oryzae.

TL;DR: This work systematically examined genome-wide sequence and functional variation between the domesticated fungus Aspergillus oryzae and its wild relative A. flavus, suggesting that whereas animal and plant domestication was largely driven by Neolithic "genetic tinkering" of developmental pathways, microbe domesticated was driven by extensive remodeling of metabolism.