Clara S. Chan

TL;DR: The authors investigated the genomic basis of vectorial capacity and explore new avenues for vector control, sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution Comparative analyses show faster rates of gene gain and loss, elevated gene shuffling on the X chromosome, and more intron losses, relative to Drosophila.

TL;DR: These studies identify distinct roles for DDK and S-CDK during helicase activation and support a model in which the leading strand DNA polymerase is recruited prior to origin DNA unwinding and RNA primer synthesis.

TL;DR: An expanded set of 283 readthrough candidates is reported, including 16 double-readthrough candidates; these were manually curated to rule out alternatives such as A-to-I editing, alternative splicing, dicistronic translation, and selenocysteine incorporation.

TL;DR: Genetic interactions between priming site mutations and MRC1 or TOF1 deletion support a role for these modifications in replication fork stability and identify regulatory mechanisms that modulate origin firing and replication fork assembly during cell cycle progression.