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Xiaofang Jiang
Researcher at National Institutes of Health
Publications - 46
Citations - 3470
Xiaofang Jiang is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Biology & Genome. The author has an hindex of 19, co-authored 32 publications receiving 2412 citations. Previous affiliations of Xiaofang Jiang include Massachusetts Institute of Technology & Virginia Tech.
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Journal ArticleDOI
Extensive introgression in a malaria vector species complex revealed by phylogenomics
Michael C. Fontaine,James B. Pease,Aaron Steele,Robert M. Waterhouse,Daniel E. Neafsey,Igor V. Sharakhov,Xiaofang Jiang,Andrew Brantley Hall,Flaminia Catteruccia,Flaminia Catteruccia,Evdoxia G. Kakani,Evdoxia G. Kakani,Sara N. Mitchell,Yi-Chieh Wu,Hilary A. Smith,R. Rebecca Love,Mara K. N. Lawniczak,Michel A. Slotman,Scott J. Emrich,Matthew W. Hahn,Nora J. Besansky +20 more
TL;DR: Pervasive autosomal introgression between these human malaria vectors, including nonsister vector species, suggests that traits enhancing vectorial capacity may be gained through interspecific gene flow, including between nonsister species.
Journal ArticleDOI
Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes
Daniel E. Neafsey,Robert M. Waterhouse,Mohammad Reza Abai,Sergey Aganezov,Max A. Alekseyev,James E. Allen,James Amon,Bruno Arcà,Peter Arensburger,Gleb N. Artemov,Lauren A. Assour,Hamidreza Basseri,Aaron M. Berlin,Bruce W. Birren,Stéphanie Blandin,Stéphanie Blandin,Andrew I. Brockman,Thomas R. Burkot,Austin Burt,Clara S. Chan,Cedric Chauve,Joanna C. Chiu,Mikkel B. Christensen,Carlo Costantini,Victoria L.M. Davidson,Elena Deligianni,Tania Dottorini,Vicky Dritsou,Stacey Gabriel,Wamdaogo M. Guelbeogo,Andrew Brantley Hall,Mira V. Han,Thaung Hlaing,Daniel S.T. Hughes,Daniel S.T. Hughes,Adam M. Jenkins,Xiaofang Jiang,Irwin Jungreis,Evdoxia G. Kakani,Evdoxia G. Kakani,Maryam Kamali,Petri Kemppainen,Ryan C. Kennedy,Ioannis K. Kirmitzoglou,Ioannis K. Kirmitzoglou,Lizette L. Koekemoer,Njoroge Laban,Nicholas Langridge,Mara K. N. Lawniczak,Manolis Lirakis,Neil F. Lobo,Ernesto Lowy,Robert M. MacCallum,Chunhong Mao,Gareth Maslen,Charles Mbogo,Jenny McCarthy,Kristin Michel,Sara N. Mitchell,Wendy Moore,Katherine A. Murphy,Anastasia N. Naumenko,Tony Nolan,Eva Maria Novoa,Samantha M. O’Loughlin,Chioma Oringanje,Mohammad Ali Oshaghi,Nazzy Pakpour,Philippos Aris Papathanos,Philippos Aris Papathanos,Ashley Peery,Michael Povelones,Anil Prakash,David P. Price,Ashok Rajaraman,Lisa J. Reimer,David C. Rinker,Antonis Rokas,Tanya L. Russell,N’Fale Sagnon,Maria V. Sharakhova,Terrance Shea,Felipe A. Simão,Felipe A. Simão,Frédéric Simard,Michel A. Slotman,Pradya Somboon,V. N. Stegniy,Claudio J. Struchiner,Claudio J. Struchiner,Gregg W.C. Thomas,Marta Tojo,Pantelis Topalis,Jose M. C. Tubio,Maria F. Unger,John Vontas,Catherine Walton,Craig S. Wilding,Judith H. Willis,Yi-Chieh Wu,Yi-Chieh Wu,Guiyun Yan,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Xiaofan Zhou,Flaminia Catteruccia,Flaminia Catteruccia,George K. Christophides,Frank H. Collins,Robert S. Cornman,Andrea Crisanti,Andrea Crisanti,Martin J. Donnelly,Martin J. Donnelly,Scott J. Emrich,Michael C. Fontaine,Michael C. Fontaine,William M. Gelbart,Matthew W. Hahn,Immo A. Hansen,Paul I. Howell,Fotis C. Kafatos,Manolis Kellis,Daniel Lawson,Christos Louis,Shirley Luckhart,Marc A. T. Muskavitch,Marc A. T. Muskavitch,José M. C. Ribeiro,Michael A. Riehle,Igor V. Sharakhov,Zhijian Tu,Laurence J. Zwiebel,Nora J. Besansky +133 more
TL;DR: The authors investigated the genomic basis of vectorial capacity and explore new avenues for vector control, sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution Comparative analyses show faster rates of gene gain and loss, elevated gene shuffling on the X chromosome, and more intron losses, relative to Drosophila.
Journal ArticleDOI
A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients
Andrew Brantley Hall,Andrew Brantley Hall,Moran Yassour,Moran Yassour,Jenny Sauk,Jenny Sauk,Ashley L. Garner,Ashley L. Garner,Xiaofang Jiang,Xiaofang Jiang,Timothy D. Arthur,Timothy D. Arthur,Georgia K. Lagoudas,Georgia K. Lagoudas,Tommi Vatanen,Tommi Vatanen,Nadine Fornelos,Nadine Fornelos,Robin G. Wilson,Madeline Bertha,Melissa Cohen,John J. Garber,Hamed Khalili,Dirk Gevers,Dirk Gevers,Dirk Gevers,Ashwin N. Ananthakrishnan,Subramaniam Kugathasan,Eric S. Lander,Eric S. Lander,Eric S. Lander,Paul C. Blainey,Paul C. Blainey,Hera Vlamakis,Hera Vlamakis,Ramnik J. Xavier,Curtis Huttenhower,Curtis Huttenhower +37 more
TL;DR: In this article, the authors performed metagenomic sequencing of monthly stool samples from 20 IBD patients and 12 controls (266 total samples) and identified strain-specific functional correlates with IBD outcomes.
Journal ArticleDOI
Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome
Arnau Vich Vila,Floris Imhann,Valerie Collij,Soesma A Jankipersadsing,Thomas Gurry,Thomas Gurry,Zlatan Mujagic,Alexander Kurilshikov,Marc Jan Bonder,Xiaofang Jiang,Xiaofang Jiang,Ettje F. Tigchelaar,Jackie A M Dekens,Vera Peters,Michiel Voskuil,Marijn C. Visschedijk,Hendrik M. van Dullemen,Daniel Keszthelyi,Morris A. Swertz,Lude Franke,Rudi Alberts,Eleonora A. M. Festen,Gerard Dijkstra,Ad A.M. Masclee,Marten H. Hofker,Ramnik J. Xavier,Ramnik J. Xavier,Eric J. Alm,Eric J. Alm,Jingyuan Fu,Cisca Wijmenga,Daisy Jonkers,Alexandra Zhernakova,Rinse K. Weersma +33 more
TL;DR: A case-control analysis using shotgun metagenomic sequencing of stool samples from 1792 individuals with IBD and IBS compared with control individuals in the general population was able to use gut microbiota composition differences to distinguish patients with I BD from those with IBS.
Journal ArticleDOI
A male-determining factor in the mosquito Aedes aegypti
Andrew Brantley Hall,Sanjay Basu,Xiaofang Jiang,Yumin Qi,Vladimir A. Timoshevskiy,James K. Biedler,Maria V. Sharakhova,Rubayet Elahi,Michelle A. E. Anderson,Xiao-Guang Chen,Igor V. Sharakhov,Zach N. Adelman,Zhijian Tu +12 more
TL;DR: It is shown that an M-locus gene, Nix, functions as an M factor in A. aegypti, and this study provides a foundation for mosquito control strategies that convert female mosquitoes into harmless males.