D
David E. Newby
Researcher at University of Edinburgh
Publications - 902
Citations - 45577
David E. Newby is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Myocardial infarction & Coronary artery disease. The author has an hindex of 98, co-authored 805 publications receiving 35865 citations. Previous affiliations of David E. Newby include NHS Lothian & Queen's University.
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Journal ArticleDOI
A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis.
S. Joanna Cowell,David E. Newby,Robin J Prescott,Peter Bloomfield,John H. Reid,David B. Northridge,Nicholas A. Boon +6 more
TL;DR: Long-term, large-scale, randomized, controlled trials are needed to establish the role of statin therapy in patients with calcific aortic stenosis, and this study cannot exclude a small reduction in the rate of disease progression or a significant reduction in major clinical end points.
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Global association of air pollution and heart failure: a systematic review and meta-analysis
Anoop S V Shah,Jeremy P. Langrish,Harish Nair,Harish Nair,David A. McAllister,Amanda Hunter,Ken Donaldson,David E. Newby,Nicholas L. Mills +8 more
TL;DR: Air pollution has a close temporal association with heart failure hospitalisation and heart failure mortality, and it should remain a key target for global health policy.
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Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure
Ken Donaldson,Lang Tran,Luis A Jimenez,Rodger Duffin,David E. Newby,Nicholas L. Mills,William MacNee,Vicki Stone +7 more
TL;DR: CDNP can be seen as a group of particulate toxins unified by a common mechanism of injury and properties of translocation which have the potential to mediate a range of adverse effects in the lungs and other organs and warrant further research.
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18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial
Nikhil Joshi,Alex T. Vesey,Michelle C. Williams,Anoop S V Shah,Patrick A. Calvert,Felicity H. Craighead,Su Ern Yeoh,William Wallace,Donald Salter,Alison Fletcher,Edwin J R van Beek,Andrew D. Flapan,Neal G. Uren,Miles Behan,Nicholas L. Cruden,Nicholas L. Mills,Keith A.A. Fox,James H.F. Rudd,Marc R. Dweck,David E. Newby +19 more
TL;DR: 18)F-NaF PET-CT is the first non-invasive imaging method to identify and localise ruptured and high-risk coronary plaque and is needed to establish whether this method can improve the management and treatment of patients with coronary artery disease.
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Adverse cardiovascular effects of air pollution
Nicholas L. Mills,Ken Donaldson,Paddy W Hadoke,Nicholas A. Boon,William MacNee,Flemming R. Cassee,Thomas Sandström,Anders Blomberg,David E. Newby +8 more
TL;DR: An increased understanding of the mediators and mechanisms of these processes is necessary if the authors are to develop strategies to protect individuals at risk and reduce the effect of air pollution on cardiovascular disease.