D
Dirkje S. Postma
Researcher at University Medical Center Groningen
Publications - 11
Citations - 835
Dirkje S. Postma is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Single-nucleotide polymorphism & Genome-wide association study. The author has an hindex of 6, co-authored 11 publications receiving 765 citations. Previous affiliations of Dirkje S. Postma include Wake Forest University.
Papers
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Journal ArticleDOI
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
Lavinia Paternoster,Marie Standl,Chih-Mei Chen,Adaikalavan Ramasamy,Klaus Bønnelykke,Liesbeth Duijts,Manuel A. R. Ferreira,Alexessander Couto Alves,Jacob P. Thyssen,Eva Albrecht,Hansjoerg Baurecht,Hansjoerg Baurecht,Bjarke Feenstra,Patrick M. A. Sleiman,Pirro G. Hysi,Nicole M. Warrington,Ivan Curjuric,Ronny Myhre,John A. Curtin,Maria M. Groen-Blokhuis,Marjan Kerkhof,Annika Sääf,Andre Franke,David Ellinghaus,Regina Foelster-Holst,Emmanouil T. Dermitzakis,Emmanouil T. Dermitzakis,Stephen B. Montgomery,Stephen B. Montgomery,Holger Prokisch,Katharina Heim,Anna-Liisa Hartikainen,Anneli Pouta,Juha Pekkanen,Alexandra I. F. Blakemore,Jessica L. Buxton,Marika Kaakinen,David L. Duffy,Pamela A. F. Madden,Andrew C. Heath,Grant W. Montgomery,Philip J. Thompson,Melanie C. Matheson,Peter N. Le Souëf,Beate St Pourcain,George Davey Smith,John Henderson,John P. Kemp,Nicholas J. Timpson,Panos Deloukas,Susan M. Ring,H-Erich Wichmann,Martina Mueller-Nurasyid,Natalija Novak,Norman Klopp,Elke Rodriguez,Wendy L. McArdle,Allan Linneberg,Torkil Menné,Ellen A. Nohr,Albert Hofman,André G. Uitterlinden,Cornelia M. van Duijin,Fernando Rivadeneira,Johan C. de Jongste,Ralf J. P. van der Valk,Matthias Wjst,Rain Jögi,Frank Geller,Heather A. Boyd,Jeff Murray,Cecilia Kim,Frank D. Mentch,Michael E. March,Massimo Mangino,Tim D. Spector,Veronique Bataille,Craig E. Pennell,Patrick G. Holt,Peter D. Sly,Carla M. T. Tiesler,Elisabeth Thiering,Thomas Illig,Medea Imboden,Medea Imboden,Wenche Nystad,Angela Simpson,Jouke-Jan Hottenga,Dirkje S. Postma,Gerard H. Koppelman,Henriette A. Smit,Cilla Söderhäll,Bo L. Chawes,Eskil Kreiner-Møller,Hans Bisgaard,Erik Melén,Erik Melén,Dorret I. Boomsma,Adnan Custovic,Bo Jacobsson,Bo Jacobsson,Nicole Probst-Hensch,Nicole Probst-Hensch,Lyle J. Palmer,Daniel Glass,Hakon Hakonarson,Hakon Hakonarson,Mads Melbye,Deborah Jarvis,Vincent W. V. Jaddoe,Christian Gieger,David P. Strachan,Nicholas G. Martin,Marjo-Riitta Järvelin,Joachim Heinrich,David M. Evans,Stephan Weidinger +116 more
TL;DR: A genome-wide association meta-analysis of affected individuals and controls and the ten most strongly associated new susceptibility loci examined underline the importance of both epidermal barrier function and immune dysregulation in atopic dermatitis pathogenesis.
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
Lavinia Paternoster,Marie Standl,Chih-Mei Chen,Adaikalavan Ramasamy,Klaus Bønnelykke,Liesbeth Duijts,Manuel A. R. Ferreira,Alexessander Couto Alves,Jacob P. Thyssen,Eva Albrecht,Hansjoerg Baurecht,Hansjoerg Baurecht,Bjarke Feenstra,Patrick M. A. Sleiman,Pirro G. Hysi,Nicole M. Warrington,Ivan Curjuric,Ronny Myhre,John A. Curtin,Maria M. Groen-Blokhuis,Marjan Kerkhof,Annika Sääf,Andre Franke,David Ellinghaus,Regina Foelster-Holst,Emmanouil T. Dermitzakis,Emmanouil T. Dermitzakis,Stephen B. Montgomery,Stephen B. Montgomery,Holger Prokisch,Katharina Heim,Anna-Liisa Hartikainen,Anneli Pouta,Juha Pekkanen,Alexandra I. F. Blakemore,Jessica L. Buxton,Marika Kaakinen,David L. Duffy,Pamela A. F. Madden,Andrew C. Heath,Grant W. Montgomery,Philip J. Thompson,Melanie C. Matheson,Peter N. Le Souëf,Beate St Pourcain,George Davey Smith,John Henderson,John P. Kemp,Nicholas J. Timpson,Panos Deloukas,Susan M. Ring,H-Erich Wichmann,Martina Mueller-Nurasyid,Natalija Novak,Norman Klopp,Elke Rodriguez,Wendy L. McArdle,Allan Linneberg,Torkil Menné,Ellen A. Nohr,Albert Hofman,André G. Uitterlinden,Cornelia M. van Duijin,Fernando Rivadeneira,Johan C. de Jongste,Ralf J. P. van der Valk,Matthias Wjst,Rain Jögi,Frank Geller,Heather A. Boyd,Jeff Murray,Cecilia Kim,Frank D. Mentch,Michael E. March,Massimo Mangino,Tim D. Spector,Veronique Bataille,Craig E. Pennell,Patrick G. Holt,Peter D. Sly,Carla M. T. Tiesler,Elisabeth Thiering,Thomas Illig,Medea Imboden,Medea Imboden,Wenche Nystad,Angela Simpson,Jouke-Jan Hottenga,Dirkje S. Postma,Gerard H. Koppelman,Henriette A. Smit,Cilla Söderhäll,Bo L. Chawes,Eskil Kreiner-Møller,Hans Bisgaard,Erik Melén,Erik Melén,Dorret I. Boomsma,Adnan Custovic,Bo Jacobsson,Bo Jacobsson,Nicole Probst-Hensch,Nicole Probst-Hensch,Lyle J. Palmer,Daniel Glass,Hakon Hakonarson,Hakon Hakonarson,Mads Melbye,Deborah Jarvis,Vincent W. V. Jaddoe,Christian Gieger,David P. Strachan,Nicholas G. Martin,Marjo-Riitta Järvelin,Joachim Heinrich,David M. Evans,Stephan Weidinger +116 more
TL;DR: This paper conducted a genome-wide association meta-analysis of 5,606 affected individuals and 20,565 controls from 16 population-based cohorts and then examined the ten most strongly associated new susceptibility loci in an additional 5,419 affected individuals from 14 studies.
Journal ArticleDOI
Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations
Timothy D. Howard,Dirkje S. Postma,Hajo Jongepier,Wendy C. Moore,Gerard H. Koppelman,Siqun L. Zheng,Jianfeng Xu,Eugene R. Bleecker,Deborah A. Meyers +8 more
TL;DR: Replication of the original ADAM33 findings in these 4 additional asthma populations suggests that this gene (and perhaps others that interact with it) is important in the development and pathogenesis of asthma.
Journal ArticleDOI
Shared genetic variants suggest common pathways in allergy and autoimmune diseases
Eskil Kreiner,Johannes Waage,Marie Standl,Susanne Brix,Tune H. Pers,Alexessander Couto Alves,Nicole M. Warrington,Nicole M. Warrington,Carla M. T. Tiesler,Elaine Fuertes,Lude Franke,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Alan James,Alan James,Angela Simpson,Joyce Y. Tung,Gerard H. Koppelman,Dirkje S. Postma,Craig E. Pennell,Marjo-Riitta Järvelin,Adnan Custovic,Nicholas J. Timpson,Manuel A. R. Ferreira,David P. Strachan,John Henderson,David A. Hinds,Hans Bisgaard,Klaus Bønnelykke +29 more
TL;DR: It is suggested that shared susceptibility loci and commonalities in pathways between allergy and autoimmune diseases, suggesting shared disease mechanisms, might help in understanding the complex relationship between these diseases, including the parallel increase in disease prevalence.
Book
Long-term intervention in chronic obstructive pulmonary disease
TL;DR: The role of Glucocorticosteroids in the Management of COPD and the role of Anticholinergics in the Treatment of COPd are highlighted.