D
David A. Hinds
Researcher at Michigan State University
Publications - 28
Citations - 3543
David A. Hinds is an academic researcher from Michigan State University. The author has contributed to research in topics: Genome-wide association study & Candidate gene. The author has an hindex of 15, co-authored 28 publications receiving 2307 citations.
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Journal ArticleDOI
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
David M. Howard,Mark Adams,Toni-Kim Clarke,Jonathan D. Hafferty,Jude Gibson,Masoud Shirali,Jonathan R. I. Coleman,Jonathan R. I. Coleman,Saskia P. Hagenaars,Saskia P. Hagenaars,Joey Ward,Eleanor M. Wigmore,Clara Alloza,Xueyi Shen,Miruna C. Barbu,Eileen Y. Xu,Heather C. Whalley,Riccardo E. Marioni,David J. Porteous,Gail Davies,Ian J. Deary,Gibran Hemani,Klaus Berger,Henning Teismann,Rajesh Rawal,Volker Arolt,Bernhard T. Baune,Udo Dannlowski,Katharina Domschke,Chao Tian,David A. Hinds,Maciej Trzaskowski,Enda M. Byrne,Stephan Ripke,Stephan Ripke,Stephan Ripke,Daniel J. Smith,Patrick F. Sullivan,Patrick F. Sullivan,Naomi R. Wray,Gerome Breen,Gerome Breen,Cathryn M. Lewis,Cathryn M. Lewis,Andrew M. McIntosh,Andrew M. McIntosh +45 more
TL;DR: A genetic meta-analysis of depression found 269 associated genes that highlight several potential drug repositioning opportunities, and relationships with depression were found for neuroticism and smoking.
Journal ArticleDOI
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Padhraig Gormley,Verneri Anttila,Verneri Anttila,Bendik S. Winsvold,Bendik S. Winsvold,Priit Palta,Tõnu Esko,Tõnu Esko,Tõnu Esko,Tune H. Pers,Kai-How Farh,Kai-How Farh,Kai-How Farh,Ester Cuenca-León,Mikko Muona,Nicholas A. Furlotte,Tobias Kurth,Tobias Kurth,Andres Ingason,George McMahon,Lannie Ligthart,Gisela M. Terwindt,Mikko Kallela,Tobias Freilinger,Tobias Freilinger,Caroline Ran,Scott G. Gordon,Anine H. Stam,Stacy Steinberg,Guntram Borck,Markku Koiranen,Lydia Quaye,Hieab H.H. Adams,Terho Lehtimäki,Antti-Pekka Sarin,Juho Wedenoja,David A. Hinds,Julie E. Buring,Julie E. Buring,Markus Schürks,Paul M. Ridker,Paul M. Ridker,Maria Gudlaug Hrafnsdottir,Hreinn Stefansson,Susan M. Ring,Jouke-Jan Hottenga,Brenda W.J.H. Penninx,Markus Färkkilä,Ville Artto,Mari A. Kaunisto,Salli Vepsäläinen,Rainer Malik,Andrew C. Heath,Pamela A. F. Madden,Nicholas G. Martin,Grant W. Montgomery,Mitja I. Kurki,Mart Kals,Reedik Mägi,Kalle Pärn,Eija Hamalainen,Hailiang Huang,Hailiang Huang,Andrea Byrnes,Andrea Byrnes,Lude Franke,Jie Huang,Evie Stergiakouli,Phil Lee,Phil Lee,Cynthia Sandor,Caleb Webber,Zameel M. Cader,Zameel M. Cader,Bertram Müller-Myhsok,Stefan Schreiber,Thomas Meitinger,Johan G. Eriksson,Johan G. Eriksson,Veikko Salomaa,Kauko Heikkilä,Elizabeth Loehrer,Elizabeth Loehrer,André G. Uitterlinden,Albert Hofman,Cornelia M. van Duijn,Lynn Cherkas,Linda M. Pedersen,Audun Stubhaug,Audun Stubhaug,Christopher Sivert Nielsen,Christopher Sivert Nielsen,Minna Männikkö,Evelin Mihailov,Lili Milani,Hartmut Göbel,Ann-Louise Esserlind,Anne Francke Christensen,Thomas Hansen,Thomas Werge,Thomas Werge,Thomas Werge,Jaakko Kaprio,Jaakko Kaprio,Arpo Aromaa,Olli T. Raitakari,Olli T. Raitakari,M. Arfan Ikram,Tim D. Spector,Marjo-Riitta Järvelin,Andres Metspalu,Christian Kubisch,David P. Strachan,Michel D. Ferrari,Andrea Carmine Belin,Martin Dichgans,Maija Wessman,Arn M. J. M. van den Maagdenberg,John-Anker Zwart,John-Anker Zwart,Dorret I. Boomsma,George Davey Smith,Kari Stefansson,Kari Stefansson,Nicholas Eriksson,Mark J. Daly,Mark J. Daly,Benjamin M. Neale,Benjamin M. Neale,Jes Olesen,Daniel I. Chasman,Daniel I. Chasman,Dale R. Nyholt,Aarno Palotie +133 more
TL;DR: For example, the authors identified 44 independent single-nucleotide polymorphisms (SNPs) significantly associated with migraine risk (P < 5 × 10−8) that mapped to 38 distinct genomic loci, including 28 loci not previously reported and a locus that to date is the first to be identified on chromosome X.
Journal ArticleDOI
Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.
Samuel E. Jones,Jessica Tyrrell,Andrew R. Wood,Robin N Beaumont,Katherine S. Ruth,Marcus A. Tuke,Hanieh Yaghootkar,Youna Hu,Maris Teder-Laving,Caroline Hayward,Till Roenneberg,James F. Wilson,James F. Wilson,Fabiola M. Del Greco,Andrew A. Hicks,Chol Shin,Chang-Ho Yun,Seung Ku Lee,Andres Metspalu,Enda M. Byrne,Philip R. Gehrman,Henning Tiemeier,Karla V. Allebrandt,Rachel M. Freathy,Anna Murray,David A. Hinds,Timothy M. Frayling,Michael N. Weedon +27 more
TL;DR: The total number of loci associated with chronotype to 22 and with sleep duration to three, and provides new insights into the biology of sleep and circadian rhythms in humans, are brought to light.
Journal ArticleDOI
Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.
Chao Tian,Bethann S. Hromatka,Amy K. Kiefer,Nicholas Eriksson,Suzanne M. Noble,Joyce Y. Tung,David A. Hinds +6 more
TL;DR: Fine-mapping analysis is applied to dissect associations in the human leukocyte antigen region, which suggests important roles of specific amino acid polymorphisms in the antigen-binding clefts, an important step toward dissecting the host genetic architecture of response to common infections.
Journal ArticleDOI
Genetic Associations with Gestational Duration and Spontaneous Preterm Birth
Ge Zhang,Bjarke Feenstra,Jonas Bacelis,Xueping Liu,Lisa M. Muglia,Julius Juodakis,Daniel Miller,Nadia K. Litterman,Pan Pan Jiang,Laura Russell,David A. Hinds,Youna Hu,Matthew T. Weirauch,Xiaoting Chen,Arun R. Chavan,Günter P. Wagner,Günter P. Wagner,Mihaela Pavlicev,Mauris C. Nnamani,Jamie Maziarz,Minna K. Karjalainen,Minna K. Karjalainen,Mika Rämet,Mika Rämet,Verena Sengpiel,Frank Geller,Heather A. Boyd,Aarno Palotie,Aarno Palotie,Aarno Palotie,Allison Momany,Bruce Bedell,Kelli K Ryckman,Johanna M. Huusko,Johanna M. Huusko,Johanna M. Huusko,Carmy Forney,Leah C. Kottyan,Mikko Hallman,Mikko Hallman,Mikko Hallman,Kari Teramo,Ellen A. Nohr,George Davey Smith,Mads Melbye,Mads Melbye,Mads Melbye,Bo Jacobsson,Louis J. Muglia +48 more
TL;DR: It is found that variants at the EBF1, EEFSEC, AGTR2, WNT4, ADCY5, and RAP2C loci were associated with gestational duration and variants atThe EBF 1, EE FSEC, and AG TR2 loci with preterm birth.