C
Carla M. T. Tiesler
Researcher at Ludwig Maximilian University of Munich
Publications - 66
Citations - 6668
Carla M. T. Tiesler is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 36, co-authored 66 publications receiving 5537 citations. Previous affiliations of Carla M. T. Tiesler include Helmholtz Zentrum München.
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Journal ArticleDOI
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
Lavinia Paternoster,Marie Standl,Johannes Waage,H. Baurecht,Melanie Hotze,David P. Strachan,John A. Curtin,Klaus Bønnelykke,Chao Tian,Atsushi Takahashi,Jorge Esparza-Gordillo,Alexessander Couto Alves,Jacob P. Thyssen,Herman T. den Dekker,Manuel A. R. Ferreira,Elisabeth Altmaier,Patrick M. A. Sleiman,Patrick M. A. Sleiman,Feng Li Xiao,Juan R. González,Juan R. González,Ingo Marenholz,Birgit Kalb,Maria Pino-Yanes,Maria Pino-Yanes,Cheng-Jian Xu,Lisbeth Carstensen,Maria M. Groen-Blokhuis,Cristina Venturini,Craig E. Pennell,Sheila J. Barton,Albert M. Levin,Ivan Curjuric,Ivan Curjuric,Mariona Bustamante,Eskil Kreiner-Møller,Gabrielle A. Lockett,Jonas Bacelis,Supinda Bunyavanich,Rachel A. Myers,Anja Matanovic,Ashok Kumar,Joyce Y. Tung,Tomomitsu Hirota,Michiaki Kubo,Wendy L. McArdle,A. John Henderson,John P. Kemp,John P. Kemp,Jie Zheng,George Davey Smith,Franz Rueschendorf,Anja Bauerfeind,Min Ae Lee-Kirsch,Andreas Arnold,Georg Homuth,Carsten Oliver Schmidt,Elisabeth Mangold,Sven Cichon,Thomas Keil,Elke Rodriguez,Annette Peters,Andre Franke,Wolfgang Lieb,Natalija Novak,Regina Foelster-Holst,Momoko Horikoshi,Juha Pekkanen,Sylvain Sebert,Lise Lotte N. Husemoen,Niels Grarup,Johan C. de Jongste,Fernando Rivadeneira,Albert Hofman,Vincent W. V. Jaddoe,Suzanne G.M.A. Pasmans,Niels J. Elbert,André G. Uitterlinden,Guy B. Marks,Philip J. Thompson,Melanie C. Matheson,Colin F. Robertson,Janina S. Ried,Jin Li,Xian Bo Zuo,X. Zheng,Xianyong Yin,Liangdan Sun,Maeve A. McAleer,Grainne M. O'Regan,Caoimhe M. R. Fahy,Linda E. Campbell,Milan Macek,Michael Kurek,Donglei Hu,Celeste Eng,Dirkje S. Postma,Bjarke Feenstra,Frank Geller,Jouke-Jan Hottenga,Christel M. Middeldorp,Pirro G. Hysi,Veronique Bataille,Tim D. Spector,Carla M. T. Tiesler,Elisabeth Thiering,Badri Pahukasahasram,James J. Yang,Medea Imboden,Scott Huntsman,Natalia Vilor-Tejedor,Caroline L Relton,Ronny Myhre,Wenche Nystad,Adnan Custovic,Scott T. Weiss,Deborah A. Meyers,Cilla Soederhaell,Erik Melén,Carole Ober,Benjamin A. Raby,Angela Simpson,Bo Jacobsson,John W. Holloway,Hans Bisgaard,Jordi Sunyer,Nicole Probst-Hensch,L. Keoki Williams,Keith M. Godfrey,Carol A. Wang,Dorret I. Boomsma,Mads Melbye,Gerard H. Koppelman,Deborah Jarvis,W.H. Irwin McLean,Alan D. Irvine,Xuejun Zhang,Hakon Hakonarson,Christian Gieger,Esteban G. Burchard,Nicholas G. Martin,Liesbeth Duijts,Allan Linneberg,Marjo-Riitta Järvelin,Markus M. Noethen,Susanne Lau,Norbert Huebner,Young-Ae Lee,Mayumi Tamari,David A. Hinds,Daniel Glass,Sara J. Brown,Joachim Heinrich,David M. Evans,Stephan Weidinger +154 more
TL;DR: This paper performed a meta-analysis of >15 million genetic variants in 21,399 cases and 95,464 controls from populations of European, African, Japanese and Latino ancestry, followed by replication in 32,059 cases and 228,628 controls from 18 studies.
Journal ArticleDOI
Genome-wide associations for birth weight and correlations with adult disease
Momoko Horikoshi,Robin N Beaumont,Felix R. Day,Nicole M. Warrington,Nicole M. Warrington,Marjolein N. Kooijman,Juan Fernández-Tajes,Bjarke Feenstra,Natalie R. van Zuydam,Kyle J. Gaulton,Kyle J. Gaulton,Niels Grarup,Jonathan P. Bradfield,David P. Strachan,Ruifang Li-Gao,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Eskil Kreiner,Rico Rueedi,Rico Rueedi,Leo-Pekka Lyytikäinen,Diana L. Cousminer,Diana L. Cousminer,Diana L. Cousminer,Ying Wu,Elisabeth Thiering,Carol A. Wang,Christian Theil Have,Jouke-Jan Hottenga,Natalia Vilor-Tejedor,Peter K. Joshi,Eileen Tai-Hui Boh,Ioanna Ntalla,Ioanna Ntalla,Niina Pitkänen,Anubha Mahajan,Elisabeth M. van Leeuwen,Raimo Joro,Vasiliki Lagou,Vasiliki Lagou,Michael Nodzenski,Louise A. Diver,Krina T. Zondervan,Mariona Bustamante,Pedro Marques-Vidal,Josep M. Mercader,Amanda J. Bennett,Nilufer Rahmioglu,Dale R. Nyholt,Ronald C.W. Ma,Claudia H. T. Tam,Wing Hung Tam,Santhi K. Ganesh,Frank J.A. van Rooij,Samuel E. Jones,Po-Ru Loh,Katherine S. Ruth,Marcus A. Tuke,Jessica Tyrrell,Andrew R. Wood,Hanieh Yaghootkar,Denise M. Scholtens,Lavinia Paternoster,Inga Prokopenko,Inga Prokopenko,Peter Kovacs,Mustafa Atalay,Sara M. Willems,Kalliope Panoutsopoulou,Xu Wang,Lisbeth Carstensen,Frank Geller,Katharina E. Schraut,Mario Murcia,Catharina E. M. van Beijsterveldt,Gonneke Willemsen,Emil V. R. Appel,Cilius Esmann Fonvig,Cæcilie Trier,Carla M. T. Tiesler,Marie Standl,Zoltán Kutalik,Zoltán Kutalik,Sílvia Bonàs-Guarch,David M. Hougaard,Friman Sánchez,David Torrents,Johannes Waage,Mads V. Hollegaard,Hugoline G. de Haan,Frits R. Rosendaal,Carolina Medina-Gomez,Susan M. Ring,Gibran Hemani,George McMahon,Neil R. Robertson,Christopher J. Groves,Claudia Langenberg,Jian'an Luan,Robert A. Scott,Jing Hua Zhao,Frank D. Mentch,Scott M. MacKenzie,Rebecca M. Reynolds,William L. Lowe,Anke Tönjes,Michael Stumvoll,Virpi Lindi,Timo A. Lakka,Cornelia M. van Duijn,Wieland Kiess,Antje Körner,Thorkild I. A. Sørensen,Harri Niinikoski,Katja Pahkala,Olli T. Raitakari,Eleftheria Zeggini,George Dedoussis,Yik Ying Teo,Seang-Mei Saw,Mads Melbye,Mads Melbye,Mads Melbye,Harry Campbell,James F. Wilson,Martine Vrijheid,Eco J. C. de Geus,Eco J. C. de Geus,Dorret I. Boomsma,Haja N. Kadarmideen,Jens-Christian Holm,Torben Hansen,Sylvain Sebert,Sylvain Sebert,Andrew T. Hattersley,Lawrence J. Beilin,John P. Newnham,Craig E. Pennell,Joachim Heinrich,Linda S. Adair,Judith B. Borja,Karen L. Mohlke,Johan G. Eriksson,Johan G. Eriksson,Elisabeth Widen,Mika Kähönen,Jorma Viikari,Terho Lehtimäki,Peter Vollenweider,Klaus Bønnelykke,Hans Bisgaard,Dennis O. Mook-Kanamori,Albert Hofman,Fernando Rivadeneira,André G. Uitterlinden,Charlotta Pisinger,Oluf Pedersen,Christine Power,Elina Hyppönen,Elina Hyppönen,Nicholas J. Wareham,Hakon Hakonarson,Eleanor Davies,Brian R. Walker,Vincent W. V. Jaddoe,Marjo-Riitta Järvelin,Struan F.A. Grant,Allan Vaag,Allan Vaag,Debbie A Lawlor,Timothy M. Frayling,George Davey Smith,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Ken K. Ong,Janine F. Felix,Nicholas J. Timpson,John R. B. Perry,David M. Evans,David M. Evans,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Rachel M. Freathy,Rachel M. Freathy +185 more
TL;DR: In this paper, the authors performed a meta-analysis of birth weight in 153,781 individuals, identifying 60 loci where fetal genotype was associated with birth weight (P < 5.5×10−8).
Journal ArticleDOI
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
Florence Demenais,Florence Demenais,Patricia Margaritte-Jeannin,Patricia Margaritte-Jeannin,Kathleen C. Barnes,William O.C.M. Cookson,Janine Altmüller,Wei Ang,R. Graham Barr,Terri H. Beaty,Allan B. Becker,John Beilby,Hans Bisgaard,Unnur S. Bjornsdottir,Eugene R. Bleecker,Klaus Bønnelykke,Dorret I. Boomsma,Emmanuelle Bouzigon,Emmanuelle Bouzigon,Christopher E. Brightling,Myriam Brossard,Myriam Brossard,Guy Brusselle,Guy Brusselle,Esteban G. Burchard,Kristin M. Burkart,Andrew Bush,Andrew Bush,Moira Chan-Yeung,Kian Fan Chung,Kian Fan Chung,Alexessander Couto Alves,John A. Curtin,Adnan Custovic,Denise Daley,Johan C. de Jongste,Blanca E. Del-Rio-Navarro,Kathleen M. Donohue,Liesbeth Duijts,Celeste Eng,Johan G. Eriksson,Martin Farrall,Yuliya Fedorova,Bjarke Feenstra,Manuel A. R. Ferreira,Maxim B. Freidin,Zofia K. Z. Gajdos,Zofia K. Z. Gajdos,Jim Gauderman,Ulrike Gehring,Frank Geller,Jon Genuneit,Sina A. Gharib,Frank D. Gilliland,Raquel Granell,Penelope E. Graves,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Tari Haahtela,Susan R. Heckbert,Dick Heederik,Joachim Heinrich,Markku Heliövaara,John Henderson,Blanca E. Himes,Hiroshi Hirose,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Albert Hofman,Patrick G. Holt,Jouke J. Hottenga,Thomas J. Hudson,Thomas J. Hudson,Jennie Hui,Medea Imboden,Medea Imboden,Vladimir P. Ivanov,Vincent W. V. Jaddoe,Alan James,Alan James,Christer Janson,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Deborah Jarvis,Graham Jones,Ingileif Jonsdottir,Ingileif Jonsdottir,Pekka Jousilahti,Michael Kabesch,Mika Kähönen,David B. Kantor,A. S. Karunas,Elza Khusnutdinova,Gerard H. Koppelman,Anita L. Kozyrskyj,Eskil Kreiner,Michiaki Kubo,Rajesh Kumar,Rajesh Kumar,Ashok Kumar,Ashok Kumar,Ashok Kumar,Mikko Kuokkanen,Mikko Kuokkanen,Lies Lahousse,Lies Lahousse,Tarja Laitinen,Catherine Laprise,Mark Lathrop,Susanne Lau,Young-Ae Lee,Young-Ae Lee,Terho Lehtimäki,Sébastien Letort,Sébastien Letort,Albert M. Levin,Guo Li,Liming Liang,Laura R. Loehr,Stephanie J. London,Daan W. Loth,Ani Manichaikul,Ingo Marenholz,Ingo Marenholz,Fernando J. Martinez,Melanie C. Matheson,Rasika A. Mathias,Kenji Matsumoto,Hamdi Mbarek,Wendy L. McArdle,Mads Melbye,Mads Melbye,Mads Melbye,Erik Melén,Erik Melén,Deborah A. Meyers,Sven Michel,Hamida Mohamdi,Hamida Mohamdi,Arthur W. Musk,Arthur W. Musk,Rachel A. Myers,Maartje A.E. Nieuwenhuis,Emiko Noguchi,George T. O'Connor,George T. O'Connor,Ludmila M. Ogorodova,Cameron D. Palmer,Cameron D. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,Julie E. Park,Craig E. Pennell,Göran Pershagen,Göran Pershagen,Alexey Polonikov,Dirkje S. Postma,Nicole Probst-Hensch,Nicole Probst-Hensch,V. P. Puzyrev,Benjamin A. Raby,Olli T. Raitakari,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Stephen S. Rich,Colin F. Robertson,Isabelle Romieu,Muhammad T. Salam,Veikko Salomaa,Vivi Schlünssen,Robert A. Scott,P. A. Selivanova,Torben Sigsgaard,Angela Simpson,Valérie Siroux,Valérie Siroux,Lewis J. Smith,Maria Solodilova,Marie Standl,Kari Stefansson,Kari Stefansson,David P. Strachan,Bruno H. Stricker,Atsushi Takahashi,Philip J. Thompson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Carla M. T. Tiesler,Dara G. Torgerson,Tatsuhiko Tsunoda,André G. Uitterlinden,Ralf J. P. van der Valk,Amaury Vaysse,Amaury Vaysse,Sailaja Vedantam,Sailaja Vedantam,Andrea von Berg,Erika von Mutius,Judith M. Vonk,Johannes Waage,Nicholas J. Wareham,Scott T. Weiss,Wendy B. White,Magnus Wickman,Magnus Wickman,Elisabeth Widen,Gonneke Willemsen,L. Keoki Williams,Inge M. Wouters,James J. Yang,Jing Hua Zhao,Miriam F. Moffatt,Carole Ober,Dan L. Nicolae +216 more
TL;DR: A meta-analysis of GWAS studies for asthma from multiancestral cohorts identifies five new loci and finds that the asthma-associated loci are enriched near enhancer marks in immune cells, suggesting a major role of these loci in the regulation of immunologically related mechanisms.
Journal ArticleDOI
Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study
Karani Santhanakrishnan Vimaleswaran,Karani Santhanakrishnan Vimaleswaran,Alana Cavadino,Diane J. Berry,Rolf Jorde,Aida Karina Dieffenbach,Chen Lu,Alexessander Couto Alves,Alexessander Couto Alves,Hiddo J.L. Heerspink,Emmi Tikkanen,J. G. Eriksson,Andrew Wong,Massimo Mangino,Kathleen A. Jablonski,Ilja M. Nolte,Denise K. Houston,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Peter J. van der Most,Dorota Pasko,Lina Zgaga,Lina Zgaga,Elisabeth Thiering,Veronique Vitart,Ross M. Fraser,Jennifer E. Huffman,Rudolf A. de Boer,Ben Schöttker,Kai-Uwe Saum,Mark I. McCarthy,Mark I. McCarthy,Josée Dupuis,Karl-Heinz Herzig,Karl-Heinz Herzig,Sylvain Sebert,Anneli Pouta,Anneli Pouta,Jaana Laitinen,Marcus E. Kleber,Gerjan Navis,Mattias Lorentzon,Karen A. Jameson,Nigel K Arden,Nigel K Arden,Jackie A. Cooper,Jayshree Acharya,Rebecca Hardy,Olli T. Raitakari,Olli T. Raitakari,Samuli Ripatti,Liana K. Billings,Jari Lahti,Clive Osmond,Brenda W.J.H. Penninx,Lars Rejnmark,Kurt Lohman,Lavinia Paternoster,Ronald P. Stolk,Dena G. Hernandez,Liisa Byberg,Emil Hagström,Håkan Melhus,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Dan Mellström,Östen Ljunggren,Ioanna Tzoulaki,Stela McLachlan,Evropi Theodoratou,Carla M. T. Tiesler,Antti Jula,Pau Navarro,Alan F. Wright,Ozren Polasek,James F. Wilson,Igor Rudan,Veikko Salomaa,Joachim Heinrich,Harry Campbell,Jacqueline F. Price,Magnus Karlsson,Lars Lind,Karl Michaëlsson,Stefania Bandinelli,Timothy M. Frayling,Catharina A. Hartman,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Stephen B. Kritchevsky,Bente L. Langdahl,Johan G. Eriksson,Jose C. Florez,Tim D. Spector,Terho Lehtimäki,Diana Kuh,Steve E. Humphries,Cyrus Cooper,Cyrus Cooper,Claes Ohlsson,Winfried März,Winfried März,Winfried März,Martin H. de Borst,Meena Kumari,Mika Kivimäki,Thomas J. Wang,Chris Power,Hermann Brenner,Guri Grimnes,Pim van der Harst,Harold Snieder,Aroon D. Hingorani,Stefan Pilz,John C. Whittaker,Marjo-Riitta Järvelin,Elina Hyppönen,Elina Hyppönen +118 more
TL;DR: In this article, the authors used a mendelian randomisation approach to test whether low plasma 25-hydroxyvitamin D (25[OH]D) concentration is causally associated with blood pressure and hypertension risk.
Journal ArticleDOI
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Momoko Horikoshi,Hanieh Yaghootkar,Dennis O. Mook-Kanamori,Dennis O. Mook-Kanamori,Ulla Sovio,Ulla Sovio,H. Rob Taal,Branwen J. Hennig,Jonathan P. Bradfield,Beate St Pourcain,David M. Evans,Pimphen Charoen,Pimphen Charoen,Marika Kaakinen,Diana L. Cousminer,Terho Lehtimäki,Eskil Kreiner-Møller,Nicole M. Warrington,Mariona Bustamante,Bjarke Feenstra,Diane J. Berry,Elisabeth Thiering,Thiemo Pfab,Thiemo Pfab,Sheila J. Barton,Beverley M. Shields,Marjan Kerkhof,Elisabeth M. van Leeuwen,Anthony J. C. Fulford,Zoltán Kutalik,Zoltán Kutalik,Jing Hua Zhao,Marcel den Hoed,Anubha Mahajan,Virpi Lindi,Liang Kee Goh,Jouke-Jan Hottenga,Ying Wu,Olli T. Raitakari,Marie Neergaard Harder,Aline Meirhaeghe,Aline Meirhaeghe,Aline Meirhaeghe,Ioanna Ntalla,Rany M. Salem,Rany M. Salem,Karen A. Jameson,Kaixin Zhou,Dorota Monies,Vasiliki Lagou,Mirna Kirin,Jani Heikkinen,Linda S. Adair,Fowzan S. Alkuraya,Ali Al-Odaib,Philippe Amouyel,Philippe Amouyel,Philippe Amouyel,Ehm A. Andersson,Amanda J. Bennett,Alexandra I. F. Blakemore,Jessica L. Buxton,Jean Dallongeville,Jean Dallongeville,Jean Dallongeville,Shikta Das,Eco J. C. de Geus,Xavier Estivill,Claudia Flexeder,Philippe Froguel,Philippe Froguel,Philippe Froguel,Frank Geller,Keith M. Godfrey,Keith M. Godfrey,Frédéric Gottrand,Christopher J. Groves,Torben Hansen,Torben Hansen,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Mads V. Hollegaard,David M. Hougaard,Elina Hyppönen,Hazel Inskip,Aaron Isaacs,Aaron Isaacs,Torben Jørgensen,Christina Kanaka-Gantenbein,John P. Kemp,Wieland Kiess,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Norman Klopp,Bridget A. Knight,Christopher W. Kuzawa,George McMahon,John P. Newnham,Harri Niinikoski,Ben A. Oostra,Louise Pedersen,Dirkje S. Postma,Susan M. Ring,Fernando Rivadeneira,Neil R. Robertson,Sylvain Sebert,Sylvain Sebert,Olli Simell,Torsten Slowinski,Carla M. T. Tiesler,Anke Tönjes,Allan Vaag,Allan Vaag,Jorma Viikari,Jacqueline M. Vink,Nadja Hawwa Vissing,Nicholas J. Wareham,Gonneke Willemsen,Daniel R. Witte,Haitao Zhang,Jianhua Zhao,James F. Wilson,Michael Stumvoll,Andrew M. Prentice,Brian F. Meyer,Ewan R. Pearson,Colin Boreham,Cyrus Cooper,Matthew W. Gillman,George Dedoussis,Luis A. Moreno,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Maiju Saarinen,Karen L. Mohlke,Dorret I. Boomsma,Seang-Mei Saw,Seang-Mei Saw,Timo A. Lakka,Antje Körner,Ruth J. F. Loos,Ken K. Ong,Peter Vollenweider,Cornelia M. van Duijn,Gerard H. Koppelman,Andrew T. Hattersley,John W. Holloway,Berthold Hocher,Joachim Heinrich,Chris Power,Mads Melbye,Mònica Guxens,Craig E. Pennell,Klaus Bønnelykke,Hans Bisgaard,Johan G. Eriksson,Elisabeth Widen,Hakon Hakonarson,André G. Uitterlinden,Anneli Pouta,Anneli Pouta,Debbie A Lawlor,George Davey Smith,Timothy M. Frayling,Mark I. McCarthy,Mark I. McCarthy,Struan F.A. Grant,Vincent W. V. Jaddoe,Marjo-Riitta Järvelin,Nicholas J. Timpson,Inga Prokopenko,Rachel M. Freathy,Rachel M. Freathy +174 more
TL;DR: The number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking, are extended and highlight genetic links between fetal growth and postnatal growth and metabolism.