F
Florian Then Bergh
Researcher at Leipzig University
Publications - 63
Citations - 2517
Florian Then Bergh is an academic researcher from Leipzig University. The author has contributed to research in topics: Medicine & Multiple sclerosis. The author has an hindex of 22, co-authored 47 publications receiving 1857 citations. Previous affiliations of Florian Then Bergh include Translational Centre for Regenerative Medicine.
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Journal ArticleDOI
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
Sven Jarius,Klemens Ruprecht,Brigitte Wildemann,Tania Kuempfel,Marius Ringelstein,Christian Geis,Ingo Kleiter,Ingo Kleiter,Christoph Kleinschnitz,Achim Berthele,Johannes Brettschneider,Kerstin Hellwig,Bernhard Hemmer,Ralf A. Linker,Ralf A. Linker,Florian Lauda,Christoph Mayer,Hayrettin Tumani,Arthur Melms,Corinna Trebst,Martin Stangel,Martin Marziniak,Frank Hoffmann,Sven Schippling,Jürgen H. Faiss,Oliver Neuhaus,Barbara Ettrich,Christian Zentner,Kersten Guthke,Ulrich Hofstadt-van Oy,Reinhard Reuss,Hannah L. Pellkofer,Ulf Ziemann,Peter Kern,Klaus Peter Wandinger,Florian Then Bergh,Tobias Boettcher,Stefan Langel,Martin Liebetrau,Paulus S. Rommer,Sabine Niehaus,Christoph Münch,Alexander Winkelmann,Uwe K Zettl U,Imke Metz,Christian Veauthier,Jörn P Sieb,C. Wilke,Hans Hartung,Orhan Aktas,Friedemann Paul +50 more
TL;DR: This study provides an overview of the clinical and paraclinical features of NMOSD in Caucasians and demonstrates a number of distinct disease characteristics in seropositive and seronegative patients.
Journal ArticleDOI
Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses.
Ingo Kleiter,Anna Gahlen,Nadja Borisow,Katrin Fischer,Klaus-Dieter Wernecke,Brigitte Wegner,Kerstin Hellwig,Florence Pache,Klemens Ruprecht,Joachim Havla,Markus Krumbholz,Tania Kümpfel,Orhan Aktas,Hans-Peter Hartung,Marius Ringelstein,Christian Geis,Christoph Kleinschnitz,Achim Berthele,Bernhard Hemmer,Klemens Angstwurm,Jan-Patrick Stellmann,Simon Schuster,Martin Stangel,Florian Lauda,Hayrettin Tumani,Christoph Mayer,Lena Zeltner,Ulf Ziemann,Ralf A. Linker,Matthias Schwab,Martin Marziniak,Florian Then Bergh,Ulrich Hofstadt-van Oy,Oliver Neuhaus,Alexander Winkelmann,Wael Marouf,Jürgen H. Faiss,Brigitte Wildemann,Friedemann Paul,Sven Jarius,Corinna Trebst +40 more
TL;DR: The frequency, sequence, and efficacy of therapies used for NMO attacks are analyzed and it is shown that certain therapies are more effective than others in cases of severe N MO attacks.
Journal ArticleDOI
Evaluation of cognitive deficits and structural hippocampal damage in encephalitis with leucine-rich, glioma-inactivated 1 antibodies
Carsten Finke,Harald Prüss,Josephine Heine,Sigrid Reuter,Ute A. Kopp,Florian Wegner,Florian Then Bergh,Sebastian Koch,Olav Jansen,Thomas F. Münte,Günther Deuschl,Klemens Ruprecht,Winfried Stöcker,Klaus-Peter Wandinger,Friedemann Paul,Thorsten Bartsch +15 more
TL;DR: The latency between disease onset and initiation of immunotherapy was significantly correlated with verbal (RAVLT recall after interference, r = −0.02) and visuospatial (Rey-Osterrieth Complex Figure Test [ROCF], delayed recall: patients, 16.0 [1.96]; controls, 25.86[1.24]; P < .001) memory deficits.
Journal ArticleDOI
Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response
Jan-Patrick Stellmann,Markus Krumbholz,Tim Friede,Anna Gahlen,Nadja Borisow,Katrin Fischer,Kerstin Hellwig,Florence Pache,Klemens Ruprecht,Joachim Havla,Tania Kümpfel,Orhan Aktas,Hans-Peter Hartung,Marius Ringelstein,Christian Geis,Christoph Kleinschnitz,Achim Berthele,Bernhard Hemmer,Klemens Angstwurm,Kim Lea Young,Simon Schuster,Martin Stangel,Florian Lauda,Hayrettin Tumani,Christoph Mayer,Lena Zeltner,Ulf Ziemann,Ralf A. Linker,Matthias Schwab,Martin Marziniak,Florian Then Bergh,Ulrich Hofstadt-van Oy,Oliver Neuhaus,Uwe K. Zettl,Jürgen H. Faiss,Brigitte Wildemann,Friedemann Paul,Sven Jarius,Corinna Trebst,Ingo Kleiter +39 more
TL;DR: Age, antibody status and possibly previous attacks predict further attacks in patients treated for NMOSD, and azathioprine and rituximab are superior to interferon-β.
Journal ArticleDOI
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation
Till F. M. Andlauer,Dorothea Buck,Gisela Antony,Antonios Bayas,Lukas Bechmann,Lukas Bechmann,Achim Berthele,Andrew T. Chan,Andrew T. Chan,Christiane Gasperi,Ralf Gold,Christiane Graetz,Jürgen Haas,Michael Hecker,Carmen Infante-Duarte,M. Knop,Tania Kümpfel,Volker Limmroth,Ralf A. Linker,Verena Loleit,Felix Luessi,Sven G. Meuth,Mark Mühlau,S. Nischwitz,Friedemann Paul,Michael Pütz,Tobias Ruck,Anke Salmen,Anke Salmen,Martin Stangel,Jan-Patrick Stellmann,Klarissa Hanja Stürner,Björn Tackenberg,Florian Then Bergh,Hayrettin Tumani,Clemens Warnke,Frank Weber,Frank Weber,Heinz Wiendl,Brigitte Wildemann,Uwe K. Zettl,Ulf Ziemann,Frauke Zipp,Janine Arloth,Peter Weber,Milena Radivojkov-Blagojevic,Markus O. Scheinhardt,Theresa Dankowski,Thomas Bettecken,Peter Lichtner,Darina Czamara,Tania Carrillo-Roa,Elisabeth B. Binder,Elisabeth B. Binder,Klaus Berger,Lars Bertram,Lars Bertram,Andre Franke,Christian Gieger,Stefan Herms,Stefan Herms,Georg Homuth,Marcus Ising,Karl-Heinz Jöckel,Tim Kacprowski,Stefan Kloiber,Matthias Laudes,Wolfgang Lieb,Christina M. Lill,Christina M. Lill,Susanne Lucae,Thomas Meitinger,Susanne Moebus,Martina Müller-Nurasyid,Markus M. Nöthen,Astrid Petersmann,Rajesh Rawal,Ulf Schminke,Konstantin Strauch,Henry Völzke,Melanie Waldenberger,Jürgen Wellmann,Eleonora Porcu,Antonella Mulas,Maristella Pitzalis,Carlo Sidore,Ilenia Zara,Francesco Cucca,Magdalena Zoledziewska,Andreas Ziegler,Andreas Ziegler,Bernhard Hemmer,Bertram Müller-Myhsok,Bertram Müller-Myhsok +93 more
TL;DR: A genome-wide association study on multiple sclerosis susceptibility in German cohorts with 4888 cases and 10,395 controls detected associations not found in larger, more heterogeneous cohorts, thus providing new clues regarding MS pathogenesis.