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Magdalena Zoledziewska

Researcher at University of Sassari

Publications -  53
Citations -  3974

Magdalena Zoledziewska is an academic researcher from University of Sassari. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 27, co-authored 48 publications receiving 3098 citations. Previous affiliations of Magdalena Zoledziewska include National Institutes of Health.

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Exome-wide association study of plasma lipids in > 300,000 individuals

Dajiang J. Liu, +288 more
- 30 Oct 2017 - 
TL;DR: It is found that beta-thalassemia trait carriers displayed lower TC and were protected from coronary artery disease (CAD), and only some mechanisms of lowering LDL-C appeared to increase risk for type 2 diabetes (T2D); and TG-lowering alleles involved in hepatic production of TG-rich lipoproteins tracked with higher liver fat, higher risk for T2D, and lower risk for CAD.
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Genetic variants regulating immune cell levels in health and disease

Valeria Orrù, +52 more
- 26 Sep 2013 - 
TL;DR: Genetic contributions to quantitative levels of 95 cell types encompassing 272 immune traits, in a cohort of 1,629 individuals from four clustered Sardinian villages are reported, connecting specific cellular phenotypes to specific genetic variants, helping to explicate their involvement in disease.
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Overexpression of the Cytokine BAFF and Autoimmunity Risk

Maristella Steri, +81 more
- 26 Apr 2017 - 
TL;DR: A TNFSF13B variant was associated with multiple sclerosis and SLE, and its effects were clarified at the population, cellular, and molecular levels.

Exome-wide association study of plasma lipids in > 300,000 individuals

Dajiang J. Liu, +226 more

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

Felix R. Day, +215 more
TL;DR: Using 1000 Genomes Project–imputed genotype data in up to ∼370,000 women, 389 independent signals for age at menarche, a milestone in female pubertal development are identified, highlighting the complexity of the genetic regulation of puberty timing and support causal links with cancer susceptibility.