F
Friedrich Koch-Nolte
Researcher at University of Hamburg
Publications - 243
Citations - 11797
Friedrich Koch-Nolte is an academic researcher from University of Hamburg. The author has contributed to research in topics: NAD+ kinase & Gene. The author has an hindex of 51, co-authored 224 publications receiving 9867 citations. Previous affiliations of Friedrich Koch-Nolte include French Institute of Health and Medical Research & University of Rouen.
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Journal ArticleDOI
Toward a unified nomenclature for mammalian ADP-ribosyltransferases
TL;DR: A new consensus nomenclature for all ADP-ribosyltransferases (ARTs) based on the catalyzed reaction and on structural features is proposed to facilitate communication between researchers both inside and outside the ADP, ribosylation field.
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Single domain antibodies: promising experimental and therapeutic tools in infection and immunity.
Janusz Wesolowski,Vanina Alzogaray,Jan Reyelt,Mandy Unger,Karla Juarez,Karla Juarez,Mariela Urrutia,Ana Cauerhff,Welbeck Danquah,Björn Rissiek,Felix Scheuplein,Nicole Schwarz,Sahil Adriouch,Olivier Boyer,Michel Seman,Alexei Licea,David V. Serreze,Fernando Alberto Goldbaum,Friedrich Haag,Friedrich Koch-Nolte +19 more
TL;DR: The results of several recent proof-of-principle studies are reviewed that open the exciting perspective of using sdAbs for modulating immune functions and for targeting toxins and microbes.
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Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics.
TL;DR: Recent developments and perspectives for applications of nanobodies and nanobody-based human heavy chain antibodies as antitumor therapeutics are discussed.
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NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor
Michel Seman,Sahil Adriouch,Felix Scheuplein,Christian Krebs,Dunja Freese,Gustavo Glowacki,Phillipe Deterre,Friedrich Haag,Friedrich Koch-Nolte +8 more
TL;DR: These results delineate an alternative mechanism for inducing T cell death and set an interesting precedent for immunoregulation via crosstalk between NAD-dependent ADP-ribosyltransferases and purinoceptors.
Journal ArticleDOI
Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.
Daniel Fernandez-Ruiz,Wei Yi Ng,Wei Yi Ng,Lauren E. Holz,Joel Z. Ma,Ali Zaid,Yik Chun Wong,Lei Shong Lau,Vanessa Mollard,Anton Cozijnsen,Nicholas Collins,Jessica Li,Jessica Li,Gayle M. Davey,Yu Kato,Sapna Devi,Roghieh Skandari,Michael Pauley,Jonathan H. Manton,Dale I. Godfrey,Asolina Braun,Szun S. Tay,Peck Szee Tan,Peck Szee Tan,David G. Bowen,Friedrich Koch-Nolte,Björn Rissiek,Francis R. Carbone,Brendan S. Crabb,Mireille H. Lahoud,Mireille H. Lahoud,Ian A. Cockburn,Scott N. Mueller,Patrick Bertolino,Geoffrey I. McFadden,Irina Caminschi,Irina Caminschi,William R. Heath +37 more
TL;DR: It is shown that by combining dendritic cell-targeted priming with liver inflammation and antigen recognition on hepatocytes, high frequencies of Trm cells could be induced and these cells were essential for protection against malaria sporozoite challenge.