G
Gönül Tanır
Researcher at Boston Children's Hospital
Publications - 146
Citations - 1698
Gönül Tanır is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 19, co-authored 133 publications receiving 1418 citations.
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Journal ArticleDOI
Inherited and acquired immunodeficiencies underlying tuberculosis in childhood.
Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Jacinta Bustamante,Jamila El-Baghdadi,Yildiz Camcioglu,Nima Parvaneh,Safaa El Azbaoui,Aomar Agader,Amal Hassani,Naima El Hafidi,Nidal Alaoui Mrani,Zineb Jouhadi,Fatima Ailal,J. Najib,Ismail Reisli,Adil Zamani,Şebnem Yosunkaya,Saniye Gulle-Girit,Alisan Yildiran,Funda Erol Cipe,Selda Hançerli Törün,Ayse Metin,Basak Yildiz Atikan,Nevin Hatipoğlu,Cigdem Aydogmus,Sara Sebnem Kilic,Figen Dogu,Neslihan Edeer Karaca,Guzide Aksu,Necil Kutukculer,Melike Keser-Emiroglu,Ayper Somer,Gönül Tanır,Caner Aytekin,Parisa Adimi,Seyed Alireza Mahdaviani,Setareh Mamishi,Aziz Bousfiha,Ozden Sanal,Davood Mansouri,Jean-Laurent Casanova,Laurent Abel,Laurent Abel,Laurent Abel +44 more
TL;DR: The conditions conferring a predisposition to childhood clinical diseases caused by mycobacteria, including not only M.tb but also weakly virulent mycOBacteria, such as BCG vaccines and environmental myc Cobacteria are reviewed.
Journal ArticleDOI
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23
Rubén Martínez-Barricarte,Janet Markle,Cindy S. Ma,Elissa K. Deenick,Noé Ramírez-Alejo,Federico Mele,Daniela Latorre,Seyed Alireza Mahdaviani,Caner Aytekin,Davood Mansouri,Vanessa L. Bryant,Vanessa L. Bryant,Vanessa L. Bryant,Fabienne Jabot-Hanin,Caroline Deswarte,Caroline Deswarte,Alejandro Nieto-Patlán,Laura Surace,Gaspard Kerner,Gaspard Kerner,Yuval Itan,Yuval Itan,Sandra Jovic,Danielle T. Avery,Natalie Wong,Geetha Rao,Etienne Patin,Etienne Patin,Satoshi Okada,Benedetta Bigio,Bertrand Boisson,Bertrand Boisson,Bertrand Boisson,Franck Rapaport,Yoann Seeleuthner,Yoann Seeleuthner,Monika Schmidt,Aydan Ikinciogullari,Figen Dogu,Gönül Tanır,Payam Tabarsi,Mohammed Reza Bloursaz,Julia K. Joseph,Avneet Heer,Xiao-Fei Kong,Mélanie Migaud,Mélanie Migaud,Tomi Lazarov,Frederic Geissmann,Frederic Geissmann,Frederic Geissmann,Bernhard Fleckenstein,Cecilia S. Lindestam Arlehamn,Alessandro Sette,Alessandro Sette,Anne Puel,Anne Puel,Anne Puel,Jean-François Emile,Esther van de Vosse,Lluis Quintana-Murci,Lluis Quintana-Murci,James P. Di Santo,Laurent Abel,Laurent Abel,Laurent Abel,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Jacinta Bustamante,Stuart G. Tangye,Federica Sallusto,Jean-Laurent Casanova +72 more
TL;DR: These experiments of nature show that human IL-12 and IL-23 are both required for optimal IFN-γ–dependent immunity to mycobacteria, both individually and much more so cooperatively.
Journal ArticleDOI
IL-12Rβ1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey.
Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Jamila El Baghdadi,Nima Parvaneh,Aziz Bousfiha,Jacinta Bustamante,Jacinta Bustamante,Jacqueline Feinberg,Jacqueline Feinberg,Arina Samarina,Arina Samarina,Audrey V. Grant,Audrey V. Grant,Lucile Janniere,Lucile Janniere,Naima El Hafidi,Amal Hassani,Daniel K. Nolan,Daniel K. Nolan,J. Najib,Yildiz Camcioglu,Nevin Hatipoğlu,Cigdem Aydogmus,Gönül Tanır,Caner Aytekin,Melike Keser,Ayper Somer,Guside Aksu,Necil Kutukculer,Davood Mansouri,Alireza Mahdaviani,Setareh Mamishi,Alexandre Alcaïs,Alexandre Alcaïs,Alexandre Alcaïs,Laurent Abel,Laurent Abel,Laurent Abel,Jean-Laurent Casanova +39 more
TL;DR: The findings suggest that IL-12Rβ1 deficiency is not a very rare cause of pediatric tuberculosis in these countries, where it should be considered in selected children with severe disease.
Journal ArticleDOI
Clinical Features of Candidiasis in Patients With Inherited Interleukin 12 Receptor β1 Deficiency
Monia Ouederni,Özden Sanal,Aydan Ikinciogullari,Ilhan Tezcan,Figen Dogu,Ithaisa Sologuren,Sigifredo Pedraza-Sánchez,Melike Keser,Gönül Tanır,Chris Nieuwhof,Elena Colino,Dinakantha S. Kumararatne,Jacov Levy,Necil Kutukculer,Caner Aytekin,Estefanía Herrera-Ramos,Micah M. Bhatti,Neslihan Edeer Karaca,Ridha Barbouche,Arnon Broides,Ekaterini Goudouris,José Luis Franco,Nima Parvaneh,Ismail Reisli,Alexis Strickler,Anna Shcherbina,Ayper Somer,Anthony W. Segal,Alfonso Angel-Moreno,Jose Luis Lezana-Fernández,Mohamed Bejaoui,Miriam Bobadilla-Del Valle,Salem Kachboura,Timothy Sentongo,Imen Ben-Mustapha,Jacinta Bustamante,Jacinta Bustamante,Capucine Picard,Capucine Picard,Anne Puel,Anne Puel,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Laurent Abel,Laurent Abel,Laurent Abel,Jean-Laurent Casanova,Carlos Rodríguez-Gallego +48 more
TL;DR: Patients who are deficient in IL-12Rβ1 may have candidiasis, usually mucocutaneous, which is frequently recurrent or persistent, andCandidiasis may be the first clinical manifestation in these patients.
Journal ArticleDOI
Presentation, complications, and treatment outcome of brucellosis in Turkish children
TL;DR: This data indicates that among children in endemic Brucella melitensis areas such as Turkey, children represent 20–25% of cases and should be considered as a public health problem.