G
Grégoire Le Gal
Researcher at Ottawa Hospital Research Institute
Publications - 89
Citations - 2869
Grégoire Le Gal is an academic researcher from Ottawa Hospital Research Institute. The author has contributed to research in topics: Pulmonary embolism & Population. The author has an hindex of 15, co-authored 87 publications receiving 1837 citations. Previous affiliations of Grégoire Le Gal include European University of Brittany & Ottawa University.
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Journal ArticleDOI
Apixaban to Prevent Venous Thromboembolism in Patients with Cancer
Marc Carrier,Karim Abou-Nassar,Ranjeeta Mallick,Vicky Tagalakis,Sudeep Shivakumar,Ariah Schattner,Philip Kuruvilla,Danny Hill,Silvana Spadafora,Katerine Marquis,Mateya Trinkaus,Anna Tomiak,Agnes Y.Y. Lee,Peter L. Gross,Alejandro Lazo-Langner,Robert El-Maraghi,Glenwood D. Goss,Grégoire Le Gal,David J. Stewart,Tim Ramsay,Marc A. Rodger,Debra Witham,Philip S. Wells,Avert Investigators +23 more
TL;DR: Apixaban therapy resulted in a significantly lower rate of venous thromboembolism than did placebo among intermediate‐to‐high‐risk ambulatory patients with cancer who were starting chemotherapy.
Journal ArticleDOI
Prevention, Diagnosis, and Treatment of VTE in Patients With Coronavirus Disease 2019: CHEST Guideline and Expert Panel Report.
Lisa K. Moores,Tobias Tritschler,Tobias Tritschler,Shari B. Brosnahan,Marc Carrier,Jacob F. Collen,Jacob F. Collen,Kevin C. Doerschug,Aaron B. Holley,Aaron B. Holley,David Jiménez,Grégoire Le Gal,Parth Rali,Philip S. Wells +13 more
TL;DR: The evidence on the optimal strategies to prevent, diagnose, and treat venous thromboembolism in patients with COVID-19 is sparse, but rapidly evolving.
Journal ArticleDOI
American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism.
Wendy Lim,Grégoire Le Gal,Shannon M. Bates,Marc Philip Righini,Marc Philip Righini,Linda B. Haramati,Eddy Lang,Eddy Lang,Jeffrey A. Kline,Sonja Chasteen,Marcia Snyder,Payal M. Patel,Meha Bhatt,Parth Patel,Cody Braun,Housne Ara Begum,Wojtek Wiercioch,Holger J. Schünemann,Reem A. Mustafa,Reem A. Mustafa +19 more
TL;DR: These evidence-based guidelines are intended to support patients, clinicians, and health care professionals in VTE diagnosis by recommending using D-dimer as the initial test and research is needed on new diagnostic modalities and on clinical decision rules for patients with suspected recurrent VTE.
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Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism
Marine Germain,Marine Germain,Marine Germain,Daniel I. Chasman,Hugoline G. de Haan,Weihong Tang,Sara Lindström,Lu-Chen Weng,Mariza de Andrade,Marieke C H De Visser,Kerri L. Wiggins,Pierre Suchon,Noémie Saut,David M. Smadja,Grégoire Le Gal,Astrid van Hylckama Vlieg,Antonio Fabio Di Narzo,Ke Hao,Christopher P. Nelson,Christopher P. Nelson,Ares Rocanin-Arjo,Ares Rocanin-Arjo,Ares Rocanin-Arjo,Lasse Folkersen,Ramin Monajemi,Lynda M. Rose,Jennifer A. Brody,Eline Slagboom,Dylan Aïssi,Dylan Aïssi,Dylan Aïssi,Jean-François Deleuze,Panos Deloukas,Christophe Tzourio,Jean-François Dartigues,Claudine Berr,Kent D. Taylor,Mete Civelek,Per Eriksson,Bruce M. Psaty,Jeanine Houwing-Duitermaat,Alison H. Goodall,Alison H. Goodall,François Cambien,François Cambien,François Cambien,Peter Kraft,Philippe Amouyel,Nilesh J. Samani,Nilesh J. Samani,Saonli Basu,Paul M. Ridker,Frits R. Rosendaal,Christopher Kabrhel,Aaron R. Folsom,John A. Heit,Pieter H. Reitsma,David-Alexandre Trégouët,David-Alexandre Trégouët,David-Alexandre Trégouët,Nicholas L. Smith,Pierre-Emmanuel Morange +61 more
TL;DR: A meta-analysis of genome-wide association studies to identify additional VTE susceptibility genes uncovered unexpected actors of VTE etiology and pave the way for novel mechanistic concepts of V TE pathophysiology.
Journal ArticleDOI
Meta-analysis of low molecular weight heparin to prevent recurrent placenta-mediated pregnancy complications
Marc A. Rodger,Marc A. Rodger,Marc Carrier,Grégoire Le Gal,Ida Martinelli,Annalisa Perna,Évelyne Rey,J.I.P. de Vries,Jean-Christophe Gris +8 more
TL;DR: A meta-analysis of randomized controlled trials comparing low-molecular-weight heparin (LMWH) vs no LMWH for the prevention of recurrent placenta-mediated pregnancy complications found LMWH may be a promising therapy for recurrent, especially severe, placentA- mediated pregnancy complications, but further research is required.