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Harro Seelaar
Researcher at Erasmus University Rotterdam
Publications - 112
Citations - 11447
Harro Seelaar is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Frontotemporal dementia & Medicine. The author has an hindex of 25, co-authored 63 publications receiving 9260 citations. Previous affiliations of Harro Seelaar include Erasmus University Medical Center.
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Journal ArticleDOI
Midcingulate involvement in progressive supranuclear palsy and tau positive frontotemporal dementia
Wang Zheng Chiu,Janne M. Papma,Inge de Koning,Laura Donker Kaat,Harro Seelaar,Ambroos E.M. Reijs,Roelf Valkema,D. Hasan,Agnita J.W. Boon,John C. van Swieten +9 more
TL;DR: The posterior part of the MCC is prominently involved in the neurodegenerative process of PSP, and the severity of its hypoperfusion correlated with the extent of executive dysfunction in FTD tau.
Journal ArticleDOI
Frontotemporal dementia: correlations between psychiatric symptoms and pathology
Marta Scarioni,Priya Gami-Patel,Yannick Timar,Harro Seelaar,John C. van Swieten,Annemieke J. M. Rozemuller,Annemieke J. M. Rozemuller,Annemiek Dols,Elio Scarpini,Elio Scarpini,Daniela Galimberti,Daniela Galimberti,J. J. M. Hoozemans,Yolande A.L. Pijnenburg,Anke A. Dijkstra +14 more
TL;DR: This study set out to investigate the relationship between pathological and clinical presentation at single symptom level, including neuropsychiatric features, in frontotemporal dementia.
Journal ArticleDOI
Symmetrical Corticobasal Syndrome Caused by a Novel c.314dup Progranulin Mutation
Elise G.P. Dopper,Harro Seelaar,Wang Zheng Chiu,Inge de Koning,Rick van Minkelen,Matt Baker,Annemieke J. M. Rozemuller,Rosa Rademakers,John C. van Swieten +8 more
TL;DR: A novel GRN mutation is found in a patient with an atypical (CBS) presentation with symmetric neuroimaging findings in an important cause of CBS associated with FTLD-TDP type 3 pathology, sometimes in sporadic cases.
Journal ArticleDOI
Differential early subcortical involvement in genetic FTD within the GENFI cohort.
Martina Bocchetta,Emily Todd,Georgia Peakman,David M. Cash,Rhian S Convery,Lucy L. Russell,David L. Thomas,Juan Eugenio Iglesias,John C. van Swieten,Lize C. Jiskoot,Harro Seelaar,Barbara Borroni,Daniela Galimberti,Raquel Sánchez-Valle,R Laforce,F. Moreno,Matthis Synofzik,Caroline Graff,M Masellis,Maria Carmela Tartaglia,James B. Rowe,Rik Vandenberghe,Elizabeth Finger,Fabrizio Tagliavini,A Mendonca,Isabel Santana,Chris R. Butler,Simon Ducharme,A. Gerhard,A. Danek,Johannes Levin,Markus Otto,Sandro Sorbi,Isabelle Le Ber,F. Pasquier,Jonathan D. Rohrer,Genetic Frontotemporal dementia Initiative +36 more
TL;DR: In this article, the extent of subcortical involvement, particularly within subregions, and how this differs between genetic groups were investigated using parcellation methods on volumetric 3-T-T1-weighted MRI scans.
Journal ArticleDOI
Brain perfusion patterns in familial frontotemporal lobar degeneration
Harro Seelaar,Janne M. Papma,Gaëtan Garraux,I. de Koning,Ambroos E.M. Reijs,Roelf Valkema,A. J. M. Rozemuller,Eric Salmon,J. C. van Swieten +8 more
TL;DR: Familial FTLD-TDP shows relatively more posterior hypoperfusion, including the precuneus and inferior parietal lobule, possibly related to significant memory impairment and post hoc analysis of families with unknown genetic defect vs MAPT revealed less perfusion in the right frontal and parietal lobe.