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Ivan Sadowski
Researcher at University of British Columbia
Publications - 65
Citations - 5275
Ivan Sadowski is an academic researcher from University of British Columbia. The author has contributed to research in topics: Transcription factor & Transcription (biology). The author has an hindex of 33, co-authored 62 publications receiving 4971 citations. Previous affiliations of Ivan Sadowski include Harvard University.
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GAL4-VP16 is an unusually potent transcriptional activator
TL;DR: It is shown that the hybrid protein (GAL4-VP16) activates transcription unusually efficiently in mammalian cells when bound close to, or at large distances from the gene, and suggested that the activating region of VP16 may be near-maximally potent.
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A vector for expressing GAL4(1–147) fusions tn mammalian cells
Ivan Sadowski,Mark Ptashne +1 more
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A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps.
TL;DR: In-frame linker insertion mutations in Fujinami avian sarcoma virus, which introduced dipeptide insertions into the most stringently conserved segment of this N-terminal domain in P130gag-fps, impaired the ability of the virus to transform rat-2 cells.
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A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Henri Marc Bourbon,Andrés Aguilera,Aseem Z. Ansari,Francisco J. Asturias,Arnold J. Berk,Stefan Björklund,T. Keith Blackwell,Tilman Borggrefe,Michael Carey,Marian Carlson,Joan W. Conaway,Ronald C. Conaway,Scott W. Emmons,Joseph D. Fondell,Leonard P. Freedman,Toshio Fukasawa,Claes M. Gustafsson,Min Han,Xi He,Paul K. Herman,Alan G. Hinnebusch,Steen Holmberg,Frank C. P. Holstege,Judith A. Jaehning,Young Joon Kim,Laurent Kuras,Achim Leutz,John T. Lis,Michael Meisterernest,Anders M. Näär,Kim Nasmyth,Jeffrey D. Parvin,Mark Ptashne,Danny Reinberg,Hans Ronne,Hans Ronne,Ivan Sadowski,Hiroshi Sakurai,Matthias Sipiczki,Paul W. Sternberg,David J. Stillman,Randy Strich,Kevin Struhl,Jasper Q. Svejstrup,Simon Tuck,Fred Winston,Robert G. Roeder,Roger D. Kornberg +47 more
TL;DR: A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II is proposed.
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GAL4 fusion vectors for expression in yeast or mammalian cells
TL;DR: Two sets of vectors are described that simplify the production of fusion proteins containing the DNA-binding domain of GAL4, a protein fragment that binds to a specific 17-bp nucleotide sequence, but is incapable of activating transcription unless fused to a protein that can contribute an activating function.