J
J. McLennan
Researcher at University of San Francisco
Publications - 2
Citations - 384
J. McLennan is an academic researcher from University of San Francisco. The author has contributed to research in topics: Breast cancer & Odds ratio. The author has an hindex of 2, co-authored 2 publications receiving 372 citations.
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Journal ArticleDOI
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
Kelly A. Metcalfe,Daphna Birenbaum-Carmeli,Jan Lubinski,Jacek Gronwald,Henry T. Lynch,Pål Møller,Parviz Ghadirian,William D. Foulkes,Jan Klijn,Eitan Friedman,Eitan Friedman,Charmaine Kim-Sing,Peter Ainsworth,B. Rosen,Susan M. Domchek,T Wagner,Nadine Tung,Siranoush Manoukian,Fergus J. Couch,Ping Sun,Steven A. Narod,M. Daly,Howard M. Saal,Kevin Sweet,Dominique Stoppa Lyonnet,A. Eisen,G. Rennen,J. McLennan,Ruth Gershoni-Baruch,Judy Garber,Shelly Cummings,J. N. Weitzel,Beth Y. Karlan,Raluca N. Kurz,Wendy McKinnon,Marie E. Wood,Dawna Gilchrist,Albert E. Chudley,Michael P. Osborne,David A. Fishman,W. S. Meschino,Edmond G. Lemire,Christine Maugard,Gordon B. Mills,Sofia D. Merajver,Daniel Rayson,J. M. Collee +46 more
TL;DR: Nearly one‐half of the women at risk for breast cancer had taken no preventive option, relying solely on screening, and there were large differences in the uptake of the different preventive options by country of residence.
Journal ArticleDOI
Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
Joanne Kotsopoulos,Jan Lubinski,Henry T. Lynch,Jan Klijn,Parviz Ghadirian,Susan L. Neuhausen,Charmaine Kim-Sing,William D. Foulkes,Pål Møller,Claudine Isaacs,Susan M. Domchek,Susan Randall,Kenneth Offit,Nadine Tung,Peter Ainsworth,Ruth Gershoni-Baruch,Andrea Eisen,Mary B. Daly,Beth Y. Karlan,Howard M. Saal,Fergus J. Couch,Barbara Pasini,T Wagner,Eitan Friedman,Eitan Friedman,Gad Rennert,Charis Eng,Charis Eng,Jeffrey N. Weitzel,Ping Sun,Steven A. Narod,Judy Garber,Michael P. Osborne,David A. Fishman,J. McLennan,Wendy McKinnon,Sofia D. Merajver,Håkan Olsson,D. Provencher,Boris Pasche,Gareth Evans,W. S. Meschino,Edmond G. Lemire,Albert E. Chudley,Daniel Rayson,C Bellati +45 more
TL;DR: It is suggested that an early first full-term birth does not confer protection against breast cancer in BRCA mutation carriers and opting for a prophylactic oophorectomy as a breast and/or ovarian cancer risk-reducing strategy should complete childbearing prior to age 40 when this prevention modality is most effective.