M
Michael P. Osborne
Researcher at Georgetown University
Publications - 6
Citations - 605
Michael P. Osborne is an academic researcher from Georgetown University. The author has contributed to research in topics: Cancer screening & Breast cancer. The author has an hindex of 4, co-authored 6 publications receiving 578 citations.
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Journal ArticleDOI
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
Kelly A. Metcalfe,Daphna Birenbaum-Carmeli,Jan Lubinski,Jacek Gronwald,Henry T. Lynch,Pål Møller,Parviz Ghadirian,William D. Foulkes,Jan Klijn,Eitan Friedman,Eitan Friedman,Charmaine Kim-Sing,Peter Ainsworth,B. Rosen,Susan M. Domchek,T Wagner,Nadine Tung,Siranoush Manoukian,Fergus J. Couch,Ping Sun,Steven A. Narod,M. Daly,Howard M. Saal,Kevin Sweet,Dominique Stoppa Lyonnet,A. Eisen,G. Rennen,J. McLennan,Ruth Gershoni-Baruch,Judy Garber,Shelly Cummings,J. N. Weitzel,Beth Y. Karlan,Raluca N. Kurz,Wendy McKinnon,Marie E. Wood,Dawna Gilchrist,Albert E. Chudley,Michael P. Osborne,David A. Fishman,W. S. Meschino,Edmond G. Lemire,Christine Maugard,Gordon B. Mills,Sofia D. Merajver,Daniel Rayson,J. M. Collee +46 more
TL;DR: Nearly one‐half of the women at risk for breast cancer had taken no preventive option, relying solely on screening, and there were large differences in the uptake of the different preventive options by country of residence.
Journal ArticleDOI
Paroxetine Is an Effective Treatment for Hot Flashes: Results From a Prospective Randomized Clinical Trial
Vered Stearns,Rebecca Slack,Nancy Greep,Ronda Henry-Tilman,Michael P. Osborne,Craig A. Bunnell,Lynda Ullmer,Ann Gallagher,Jennifer Cullen,Edmund A. Gehan,Daniel F. Hayes,Claudine Isaacs +11 more
TL;DR: Paroxetine is an effective treatment for hot flashes in women with or without a prior breast cancer and was associated with a significant improvement in sleep compared with placebo.
Journal ArticleDOI
Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
Joanne Kotsopoulos,Jan Lubinski,Henry T. Lynch,Jan Klijn,Parviz Ghadirian,Susan L. Neuhausen,Charmaine Kim-Sing,William D. Foulkes,Pål Møller,Claudine Isaacs,Susan M. Domchek,Susan Randall,Kenneth Offit,Nadine Tung,Peter Ainsworth,Ruth Gershoni-Baruch,Andrea Eisen,Mary B. Daly,Beth Y. Karlan,Howard M. Saal,Fergus J. Couch,Barbara Pasini,T Wagner,Eitan Friedman,Eitan Friedman,Gad Rennert,Charis Eng,Charis Eng,Jeffrey N. Weitzel,Ping Sun,Steven A. Narod,Judy Garber,Michael P. Osborne,David A. Fishman,J. McLennan,Wendy McKinnon,Sofia D. Merajver,Håkan Olsson,D. Provencher,Boris Pasche,Gareth Evans,W. S. Meschino,Edmond G. Lemire,Albert E. Chudley,Daniel Rayson,C Bellati +45 more
TL;DR: It is suggested that an early first full-term birth does not confer protection against breast cancer in BRCA mutation carriers and opting for a prophylactic oophorectomy as a breast and/or ovarian cancer risk-reducing strategy should complete childbearing prior to age 40 when this prevention modality is most effective.
Ophira M. GinsburgCharmaine Kim-SingWilliam D. Foulkes • Parviz GhadirianHenry T. LynchPing SunSteven A. Narod • Hereditary Breast Cancer Clinical Study Group
Olufunmilayo I Olopade,Nadine Tung,Fergus J. Couch,Eitan Friedman,Andrea Eisen,Susan M. Domchek,Ruth Gershoni-Baruch,David Horsman,Howard M. Saal,Wendy S. Meschino,Kenneth Offit,Mark E. Robson,Michael P. Osborne,Dawna Gilchrist,Jeffrey N. Weitzel,Wendy McKinnon,Peter Ainsworth,M. B. Daly,Judy Garber,Kevin Sweet,Beth Karlan,Raluca Kurz,Claudine Isaacs,Susan L. Neuhausen,Siranoush Manoukian,Susan Armel,Rochelle Demsky,Jane McLennan,Ophira Ginsburg,Ginsburg P. Sun,Steven A. Narod,Charmaine Kim-Sing,W. D. Foulkes,Parviz Ghadirian,Henry T. Lynch,Dalla Lana +35 more
TL;DR: BRCA2 mutation carriers are at increased risk for skin cancer, compared with BRCA1 carriers, in par- ticular for basal cell carcinoma.
Journal ArticleDOI
Discussions of cancer screening: What do physicians say, what do patients hear, and how much shared decision making occurs?
James A. Talcott,Gina Aharonoff,Maureen Bezuhly,Jessica Herzstein,Michael P. Osborne,Floyd J. Fowler +5 more
TL;DR: Even immediately after the encounter, many patients and physicians recalled whether screening had been discussed and recommendations differently, and most SDM discussions were incomplete.