E
Edmond G. Lemire
Researcher at University of Saskatchewan
Publications - 58
Citations - 1452
Edmond G. Lemire is an academic researcher from University of Saskatchewan. The author has contributed to research in topics: Breast cancer & Gene. The author has an hindex of 15, co-authored 57 publications receiving 1294 citations. Previous affiliations of Edmond G. Lemire include Royal University Hospital.
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Journal ArticleDOI
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
Kelly A. Metcalfe,Daphna Birenbaum-Carmeli,Jan Lubinski,Jacek Gronwald,Henry T. Lynch,Pål Møller,Parviz Ghadirian,William D. Foulkes,Jan Klijn,Eitan Friedman,Eitan Friedman,Charmaine Kim-Sing,Peter Ainsworth,B. Rosen,Susan M. Domchek,T Wagner,Nadine Tung,Siranoush Manoukian,Fergus J. Couch,Ping Sun,Steven A. Narod,M. Daly,Howard M. Saal,Kevin Sweet,Dominique Stoppa Lyonnet,A. Eisen,G. Rennen,J. McLennan,Ruth Gershoni-Baruch,Judy Garber,Shelly Cummings,J. N. Weitzel,Beth Y. Karlan,Raluca N. Kurz,Wendy McKinnon,Marie E. Wood,Dawna Gilchrist,Albert E. Chudley,Michael P. Osborne,David A. Fishman,W. S. Meschino,Edmond G. Lemire,Christine Maugard,Gordon B. Mills,Sofia D. Merajver,Daniel Rayson,J. M. Collee +46 more
TL;DR: Nearly one‐half of the women at risk for breast cancer had taken no preventive option, relying solely on screening, and there were large differences in the uptake of the different preventive options by country of residence.
Journal ArticleDOI
Clinical and mutational spectrum of neurofibromatosis type 1-like syndrome.
Ludwine Messiaen,S. Yao,Hilde Brems,Tom Callens,Achara Sathienkijkanchai,Ellen Denayer,Emily Spencer,Pamela Arn,Dusica Babovic-Vuksanovic,Carolyn Bay,Gary Bobele,Bruce H. Cohen,Luis F. Escobar,Deborah L. Eunpu,Theresa A. Grebe,Robert M. Greenstein,Rachel K. Hachen,Mira Irons,David Kronn,Edmond G. Lemire,Kathleen A. Leppig,Cynthia Lim,Marie T. McDonald,Vinodh Narayanan,Amy Pearn,Robert Pedersen,Berkley R. Powell,Lawrence R. Shapiro,David Skidmore,David Tegay,Heidi Thiese,Elaine H. Zackai,Raymon Vijzelaar,Koji Taniguchi,Koji Taniguchi,Toranoshin Ayada,Fuyuki Okamoto,Akihiko Yoshimura,Akihiko Yoshimura,Annabel H. A. Parret,Bruce R. Korf,Eric Legius +41 more
TL;DR: A high SPRED1 mutation detection rate was found in NF1 mutation-negative families with an autosomal dominant phenotype of CALMs with or without freckling and no other NF1 features, and NFLS was not associated with the peripheral and central nervous system tumors seen inNF1.
Journal ArticleDOI
GPSM2 Mutations Cause the Brain Malformations and Hearing Loss in Chudley-McCullough Syndrome
Dan Doherty,Albert E. Chudley,Gail Coghlan,Gisele E. Ishak,A. Micheil Innes,Edmond G. Lemire,R. Curtis Rogers,Aizeddin A. Mhanni,Ian G. Phelps,Steven J.M. Jones,Shing Hei Zhan,Anthony P. Fejes,Hashem Shahin,Moien Kanaan,Hatice Akay,Mustafa Tekin,Mustafa Tekin,Barbara Triggs-Raine,Teresa Zelinski +18 more
TL;DR: The gene product, GPSM2, is required for orienting the mitotic spindle during cell division in multiple tissues, suggesting that the sensorineural hearing loss and characteristic brain malformations of CMS are due to defects in asymmetric cell divisions during development.
Journal ArticleDOI
Nonspecific interstitial pneumonia and usual interstitial pneumonia with mutation in surfactant protein C in familial pulmonary fibrosis.
Rajni Chibbar,Francis Shih,Monica Båga,Emina Torlakovic,Kumar Ramlall,Robert Skomro,Donald W. Cockcroft,Edmond G. Lemire +7 more
TL;DR: Observations suggest that individuals with this particular mutation in surfactant protein C gene might be at increased risk of interstitial lung disease of variety of types.
Journal ArticleDOI
Further expansion of the phenotypic spectrum associated with mutations in ALDH18A1, encoding Δ¹-pyrroline-5-carboxylate synthase (P5CS).
David Skidmore,David Chitayat,Timothy R. Morgan,Alek Hinek,Bjoern Fischer,Aikaterini Dimopoulou,Gino R. Somers,William Halliday,Susan Blaser,Yenge Diambomba,Edmond G. Lemire,Uwe Kornak,Stephen P. Robertson +12 more
TL;DR: The findings presented here emphasize the pleiotropic presentation of this group of conditions and suggest that multiple components of the extracellular matrix are perturbed in these disorders.