Jelena-R. Ghadri

TL;DR: It is demonstrated that TTS can either be benign or a life-threating condition depending on the inciting stress factor, and a new classification based on triggers is proposed, which can serve as a clinical tool to predict short- and long-term outcomes of TTS.

TL;DR: Atypical TTS has different characteristics than typical TTS, including younger age of onset, more frequent ST-segment depression, higher prevalence of neurologic diseases, less pronounced reduction in left ventricular ejection fraction, and lower brain natriuretic peptide values on admission.

TL;DR: The data illustrate that TTS can be triggered by not only negative but also positive life events, and suggests that happy and sad life events may share similar final common emotional pathways, which can ultimately trigger TTS.

TL;DR: A clinical score is developed to estimate the probability of takotsubo syndrome and to distinguish TTS from ACS in the acute stage.

TL;DR: Current knowledge on the aetiology, presentation and treatment of Takotsubo syndrome is summarized.