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Jon Lindstrom

Researcher at University of Pennsylvania

Publications -  442
Citations -  50369

Jon Lindstrom is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Acetylcholine receptor & Nicotinic agonist. The author has an hindex of 108, co-authored 441 publications receiving 48999 citations. Previous affiliations of Jon Lindstrom include University of California, San Diego & University of California, Riverside.

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Journal ArticleDOI

β3 subunits promote expression and nicotine-induced Up-regulation of human nicotinic α6* nicotinic acetylcholine receptors expressed in transfected cell lines

TL;DR: It is demonstrated that both cell type and the accessory subunit β3 can play important roles in α6* AChR expression, stability, and up-regulation by nicotine.
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Refinement of the localization of the gene for neuronal nicotinic acetylcholine receptor α4 subunit (CHRNA4) to human chromosome 20q13.2-q13.3

TL;DR: Using a human fetal brain genomic library and a P1 clone library from Genome Systems Inc, a cosmid and P1-clone walk has been initiated from the polymorphic markers D20S19, D20s20, D 20S24, and D20 S73.
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Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study.

TL;DR: Two polymorphisms in the extracellular domain of the leptin receptor predicted the conversion to type 2 diabetes in high-risk individuals with IGT and the Del/Ins polymorphism in the 3′UTR of LEPR was associated with body weight.
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Associations between childhood refraction and parental smoking.

TL;DR: The associations of less prevalent myopia and a more hyperopic mean refraction with both prenatal and childhood exposures to tobacco smoke suggest that nongenetic, environmental exposures may have long-term influences on refraction and that further study of the role of nicotinic acetylcholine receptors in refractive development is warranted.