J
Jon Lindstrom
Researcher at University of Pennsylvania
Publications - 442
Citations - 50369
Jon Lindstrom is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Acetylcholine receptor & Nicotinic agonist. The author has an hindex of 108, co-authored 441 publications receiving 48999 citations. Previous affiliations of Jon Lindstrom include University of California, San Diego & University of California, Riverside.
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Journal ArticleDOI
Immunization of bm12 Mice with High Doses of Acetylcholine Receptor Overcomes Their Resistance to Experimental Autoimmune Myasthenia Gravisa
Peter I. Karachunski,Norma Ostlie,Sijin Lei,David K. Okita,Jon Lindstrom,Bianca M. Conti-Fine +5 more
Journal ArticleDOI
Potentiation of acetylcholine receptors by divalent cations.
TL;DR: These studies are helping to reveal how movements initiated by agonist binding to ACh binding sites are propagated through the extracellular domain of AChRs to regulate opening of the cation channel through the membrane.
Journal ArticleDOI
Differential localization of acetylcholinesterase in relation to pre- and postsynaptic nicotinic receptors in the chick brain.
TL;DR: Immunofluorescence and confocal microscopy were combined to study the distribution of acetylcholinesterase in relation to the localization of the beta2 subunit of the nicotinic acetylCholine receptors in the chick brain, finding that data may represent a morphological substrate for possible differential actions of acetolcholiersterase at presynaptic and postsynaptic nicotinics sites.
-Conotoxin PIA Is Selective for6 Subunit-Containing Nicotinic Acetylcholine Receptors
Cheryl Dowell,Baldomero M. Olivera,James E. Garrett,Sarah T. Staheli,Maren Watkins,Alexander Kuryatov,Doju Yoshikami,Jon Lindstrom,J. Michael Mcintosh +8 more
TL;DR: The predicted peptide, α-conotoxin PIA, potently blocks the chimeric α6/α3β2β3 subunit combination as expressed in oocytes but neither the muscle nor the major neuronal nAChR α4β2.