J
Jon Lindstrom
Researcher at University of Pennsylvania
Publications - 442
Citations - 50369
Jon Lindstrom is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Acetylcholine receptor & Nicotinic agonist. The author has an hindex of 108, co-authored 441 publications receiving 48999 citations. Previous affiliations of Jon Lindstrom include University of California, San Diego & University of California, Riverside.
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Journal ArticleDOI
Bipolar cells of the chick retina containing α-bungarotoxin-sensitive nicotinic acetylcholine receptors
TL;DR: Two distinct groups of cholinoceptive bipolar cells exist in the chick retina, one that contains PKC-LI, and another one that does not.
Journal ArticleDOI
Ion channel modulation as the basis for general anesthesia.
Toshio Narahashi,Gary L. Aistrup,Jon Lindstrom,William Marszalec,Keiichi Nagata,Fan Wang,Jay Z. Yeh +6 more
TL;DR: Modulation of the function of the GABA(A) and neuronal nicotinic acetylcholine receptor channels caused by general anesthetics and modulation of the glutamate receptor-channel by halothane, enflurane, isofluranes, and n-octanol was channel state-dependent.
Journal ArticleDOI
Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function.
Heidi C. O'Neill,Duncan Laverty,Natalie E. Patzlaff,Bruce N. Cohen,Carlos Fonck,Sheri McKinney,J. Michael McIntosh,Jon Lindstrom,Henry A. Lester,Sharon R. Grady,Michael J. Marks +10 more
TL;DR: Investigating changes in nicotinic receptor function and expression that may explain the behavioral phenotype of β2VL mice indicates decreases in maximal response for certain measures are larger than expected given the decrease in receptor expression.
Journal Article
Glucose tolerance and cardiovascular mortality
Aulikki Nissinen,Juha Pekkanen,Jaakko Tuomilehto,Pekka Jousilahti,Jon Lindstrom,Johan G. Eriksson,Qiao Q +6 more
TL;DR: The Diabetes Epidemiology: Collaborative Analysis of Diagnostic Criteria in Europe study showed that asymptomatic diabetes as well as impaired glucose tolerance, detected by elevated 2-hour glucose, increased the risk of death from cardiovascular causes and all causes, independently of other known risk factors and the level of fasting glucose.
Journal ArticleDOI
Inhibition of acetylcholine receptor assembly by activity in primary cultures of embryonic rat muscle cells.
TL;DR: This study examines the synthesis and post-translational fate of receptor alpha subunit in actively contracting and tetrodotoxin-inhibited rat muscle cultures and finds that in active and inactive cultures, newly synthesized subunit acquires the ability to bind alpha-bungarotoxin with the same kinetics.