J
Jon Lindstrom
Researcher at University of Pennsylvania
Publications - 442
Citations - 50369
Jon Lindstrom is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Acetylcholine receptor & Nicotinic agonist. The author has an hindex of 108, co-authored 441 publications receiving 48999 citations. Previous affiliations of Jon Lindstrom include University of California, San Diego & University of California, Riverside.
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Pathological mechanisms in experimental autoimmune myasthenia gravis. II. Passive transfer of experimental autoimmune myasthenia gravis in rats with anti-acetylcholine recepotr antibodies.
TL;DR: Passive transfer of experimental autoimmune myasthenia gravis (EAMG) was achieved using the gamma globulin fraction and purified IgG from sera of rats immunized with Electrophus electricus (eel) acetylcholine receptor (AChR) to demonstrate the critical role of anti- AChR antibodies in impairing neuromuscular transmission in EAMG.
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Effect of fibroblast growth factor on the division and fusion of bovine myoblasts.
TL;DR: Growth hormone, insulin and testosterone did not have significant effects on DNA synthesis in bovine myoblasts when compared to the FGF and FGF did not stimulate the proliferation of chick embryo myoblast, indicating that it is not active in all vertebrate species.
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Roles of Accessory Subunits in α4β2* Nicotinic Receptors
TL;DR: It is shown that both α5 and β3 efficiently assemble in human α4β2* AChRs expressed in permanently transfected human embryonic kidney (HEK) cell lines, which may explain why α5 or β3 seem to be transcribed at low levels in brain.
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Molecular studies of the neuronal nicotinic acetylcholine receptor family.
TL;DR: Certainly, the studies of these receptors are in rapid flux, with the availability of monoclonal antibody probes for localizing, purifying, and characterizing the proteins, and cDNA probes for determining sequences, localizing mRNAs, expressing functional receptors, and studying genetic regulation.
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Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures
Natasha Moser,Naguib Mechawar,I. Jones,A. Gochberg-Sarver,Avi Orr-Urtreger,Markus Plomann,Ramiro Salas,B. Molles,L. Marubio,U. Roth,Uwe Maskos,Ursula H. Winzer-Serhan,Jean-Pierre Bourgeois,A.-M. Le Sourd,M. De Biasi,Hannsjörg Schröder,Jon Lindstrom,Alfred Maelicke,Jean-Pierre Changeux,Andrea Wevers +19 more
TL;DR: Unexpectedly, for each of the antibodies tested, immunoreactivity was the same in wild‐type and knock‐out mice, implying that these antibodies are not suited for immunolocalization.