Juan E. Abrahante

TL;DR: Genome analysis identifies extremely streamlined metabolic pathways and a reliance on the host for nutrients in the parasite, which lacks an apicoplast and its genome, and possesses a degenerate mitochondrion that has lost its genome.

TL;DR: It is suggested that the relative timing of the IFN-I response and maximal virus replication is key in determining outcomes, at least in infected mice, and IFn-αβ or combination therapy may need to be used cautiously to treat viral infections in clinical settings.

TL;DR: Examination of the hb 3'UTR reveals potential binding sites for known fly miRNAs and finds that hbl-1/lin-57 is regulated by let-7, at least in the nervous system, which suggests evolutionary conservation of hunchback genes may include temporal control of cell fate specification and microRNA-mediated regulation.

TL;DR: Various hypotheses that might account for rapid expansion and diversification ofPRRSV are explored, including mechanisms specific to PRRSV and other arteriviruses, cellular modification processes, and immunological selection.

TL;DR: It is demonstrated that EditR is a robust, inexpensive tool that will facilitate the broad application of base editing technology, thereby fostering further innovation in this burgeoning field of gene editing.