K
Katja Kivinen
Researcher at University of Cambridge
Publications - 53
Citations - 3747
Katja Kivinen is an academic researcher from University of Cambridge. The author has contributed to research in topics: Preeclampsia & Gene. The author has an hindex of 22, co-authored 44 publications receiving 3237 citations. Previous affiliations of Katja Kivinen include Karolinska Institutet & Wellcome Trust Sanger Institute.
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Journal ArticleDOI
Global transcriptional responses of fission yeast to environmental stress
Dongrong Chen,W. Mark Toone,Juan Mata,Rachel Lyne,Gavin Burns,Katja Kivinen,Alvis Brazma,Nic Jones,Jürg Bähler +8 more
TL;DR: Transcriptional responses of the fission yeast Schizosaccharomyces pombe to various environmental stresses were explored and promoter motifs associated with some of the groups of coregulated genes were identified.
Journal ArticleDOI
Periodic gene expression program of the fission yeast cell cycle
Gabriella Rustici,Juan Mata,Katja Kivinen,Pietro Liò,Christopher J. Penkett,Gavin Burns,Jacqueline Hayles,Alvis Brazma,Paul Nurse,Paul Nurse,Jürg Bähler +10 more
TL;DR: The genome-wide transcriptional program of the Schizosaccharomyces pombe cell cycle was studied in this paper, identifying 407 periodically expressed genes of which 136 show high-amplitude changes.
Journal ArticleDOI
The African Genome Variation Project shapes medical genetics in Africa
Deepti Gurdasani,Tommy Carstensen,Tommy Carstensen,Fasil Tekola-Ayele,Luca Pagani,Ioanna Tachmazidou,Konstantinos Hatzikotoulas,Savita Karthikeyan,Savita Karthikeyan,Louise Iles,Martin O. Pollard,Ananyo Choudhury,Graham R. S. Ritchie,Yali Xue,Jennifer L. Asimit,Rebecca N. Nsubuga,Elizabeth H. Young,Elizabeth H. Young,Cristina Pomilla,Cristina Pomilla,Katja Kivinen,K Rockett,Anatoli Kamali,Ayo P. Doumatey,Gershim Asiki,Janet Seeley,Fatoumatta Sisay-Joof,Muminatou Jallow,Stephen Tollman,Ephrem Mekonnen,Rosemary Ekong,Tamiru Oljira,Neil Bradman,Kalifa Bojang,Michèle Ramsay,Adebowale Adeyemo,Endashaw Bekele,Ayesha A. Motala,Shane A. Norris,Fraser J. Pirie,Pontiano Kaleebu,Dominic P. Kwiatkowski,Chris Tyler-Smith,Charles N. Rotimi,Eleftheria Zeggini,Manjinder S. Sandhu,Manjinder S. Sandhu +46 more
TL;DR: It is shown that modern imputation panels (sets of reference genotypes from which unobserved or missing genotypes in study sets can be inferred) can identify association signals at highly differentiated loci across populations in sub-Saharan Africa.
Journal ArticleDOI
Genome-wide and fine-resolution association analysis of malaria in West Africa
Muminatou Jallow,Yik Ying Teo,Yik Ying Teo,Kerrin S. Small,Kerrin S. Small,Kirk A. Rockett,Kirk A. Rockett,Panos Deloukas,Taane G. Clark,Taane G. Clark,Katja Kivinen,Kalifa Bojang,David J. Conway,Margaret Pinder,Giorgio Sirugo,Fatou Sisay-Joof,Stanley Usen,Sarah Auburn,Sarah Auburn,Suzannah Bumpstead,Susana Campino,Susana Campino,Alison J. Coffey,Andrew Dunham,Andrew E. Fry,Angela Green,Rhian Gwilliam,Sarah E. Hunt,Michael Inouye,Anna E. Jeffreys,Alieu Mendy,Aarno Palotie,Simon C. Potter,Jiannis Ragoussis,Jane Rogers,Kate Rowlands,Elilan Somaskantharajah,Pamela Whittaker,Claire Widden,Peter Donnelly,Bryan Howie,Jonathan Marchini,Andrew P. Morris,Miguel A. Sanjoaquin,Miguel A. Sanjoaquin,Eric A. Achidi,Tsiri Agbenyega,Angela Allen,Angela Allen,Olukemi K. Amodu,Patrick H. Corran,Abdoulaye A. Djimde,Amagana Dolo,Ogobara K. Doumbo,Chris Drakeley,Sarah J. Dunstan,Jennifer Evans,Jennifer Evans,Jeremy Farrar,Deepika Fernando,Tran Tinh Hien,Rolf D. Horstmann,Muntaser E. Ibrahim,Nadira D. Karunaweera,Gilbert Kokwaro,Kwadwo A. Koram,Martha M. Lemnge,Julie Makani,Kevin Marsh,Pascal Michon,David Modiano,Malcolm E. Molyneux,Ivo Mueller,Michael Parker,Norbert Peshu,Christopher V. Plowe,Odile Puijalon,John C. Reeder,Hugh Reyburn,Eleanor M. Riley,Anavaj Sakuntabhai,Pratap Singhasivanon,Sodiomon B. Sirima,Adama Tall,Terrie E. Taylor,Mahamadou A. Thera,Marita Troye-Blomberg,Thomas N. Williams,Michael T. Wilson,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +90 more
TL;DR: These findings provide proof of principle that fine-resolution multipoint imputation, based on population-specific sequencing data, can substantially boost authentic GWA signals and enable fine mapping of causal variants in African populations.
Journal ArticleDOI
Resistance to malaria through structural variation of red blood cell invasion receptors
Ellen M. Leffler,Ellen M. Leffler,Gavin Band,Gavin Band,George B.J. Busby,Katja Kivinen,Quang Si Le,Geraldine M. Clarke,Kalifa Bojang,David J. Conway,David J. Conway,Muminatou Jallow,Muminatou Jallow,Fatoumatta Sisay-Joof,Edith C. Bougouma,Valentina D. Mangano,David Modiano,Sodiomon B. Sirima,Eric A. Achidi,Tobias O. Apinjoh,Kevin Marsh,Carolyne M. Ndila,Norbert Peshu,Thomas N. Williams,Thomas N. Williams,Chris Drakeley,Alphaxard Manjurano,Alphaxard Manjurano,Hugh Reyburn,Eleanor M. Riley,David Kachala,Malcolm E. Molyneux,Malcolm E. Molyneux,Vysaul Nyirongo,Terrie Taylor,Nicole Thornton,Louise Tilley,Shane Grimsley,Eleanor Drury,Jim Stalker,Victoria Cornelius,Christina Hubbart,Anna E. Jeffreys,Kate Rowlands,Kirk A. Rockett,Kirk A. Rockett,Chris C. A. Spencer,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +48 more
TL;DR: A complex CNV called DUP4 is associated with resistance to severe malaria and fully explains the previously reported signal of association, and a systematic catalog of CNVs is provided, describing structural diversity that may have functional importance at this locus.