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Karl Peter Giese

Researcher at King's College London

Publications -  78
Citations -  7447

Karl Peter Giese is an academic researcher from King's College London. The author has contributed to research in topics: Ca2+/calmodulin-dependent protein kinase & Long-term potentiation. The author has an hindex of 38, co-authored 73 publications receiving 6980 citations. Previous affiliations of Karl Peter Giese include École Polytechnique Fédérale de Lausanne & Cold Spring Harbor Laboratory.

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Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning.

TL;DR: The autophosphorylation of alphaCaMKII at Thr286 appears to be required for LTP and learning.
Journal ArticleDOI

Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain

TL;DR: Cloning and sequencing of cDNAs isolated from a rat cortex cDNA library reveals that a gene family encodes several highly homologous K+ channel forming (RCK) proteins, which suggest the molecular basis for the diversity of voltage‐gated K+ channels in mammalian brain is based on the expression of several RCK proteins by a family of genes.
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Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

TL;DR: It is demonstrated that P0 is essential for the normal spiraling, compaction, and maintenance of the peripheral myelin sheath and the continued integrity of associated axons and suggested that this protein conveys a signal that regulates Schwann cell gene expression.