K
Karl Peter Giese
Researcher at King's College London
Publications - 78
Citations - 7447
Karl Peter Giese is an academic researcher from King's College London. The author has contributed to research in topics: Ca2+/calmodulin-dependent protein kinase & Long-term potentiation. The author has an hindex of 38, co-authored 73 publications receiving 6980 citations. Previous affiliations of Karl Peter Giese include École Polytechnique Fédérale de Lausanne & Cold Spring Harbor Laboratory.
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Journal ArticleDOI
Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning.
TL;DR: The autophosphorylation of alphaCaMKII at Thr286 appears to be required for LTP and learning.
Journal ArticleDOI
Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain
Walter Stühmer,J. P. Ruppersberg,Klaus-Hasso Schro̊ter,Bert Sakmann,M. Stocker,Karl Peter Giese,A. Perschke,A. Baumann,Olaf Pongs +8 more
TL;DR: Cloning and sequencing of cDNAs isolated from a rat cortex cDNA library reveals that a gene family encodes several highly homologous K+ channel forming (RCK) proteins, which suggest the molecular basis for the diversity of voltage‐gated K+ channels in mammalian brain is based on the expression of several RCK proteins by a family of genes.
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Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons
TL;DR: It is demonstrated that P0 is essential for the normal spiraling, compaction, and maintenance of the peripheral myelin sheath and the continued integrity of associated axons and suggested that this protein conveys a signal that regulates Schwann cell gene expression.
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Mutant mice and neuroscience: Recommendations concerning genetic background
Alcino J. Silva,Elizabeth M. Simpson,Joseph S. Takahashi,Hans-Peter Lipp,Shigetada Nakanishi,Jeanne M. Wehner,Karl Peter Giese,Tim Tully,Ted Abel,Paul F. Chapman,Kevin Fox,Seth G. N. Grant,Shigeyoshi Itohara,Richard Lathe,Mark Mayford,James O. McNamara,Roger J. Morris,Marina R. Picciotto,John C. Roder,Hee-Sup Shin,Paul A. Slesinger,Daniel R. Storm,Michael P. Stryker,Susumu Tonegawa,Yanyan Wang,David P. Wolfer +25 more
TL;DR: The following scientists made significant contributions to the recommendations in the report on climate change made by the United Nations Educational, Scientific and Cultural Organization (UNESCO) in 2016.
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Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin.
Dirk Montag,Karl Peter Giese,Udo Bartsch,Rudolf Martini,Yolande Lang,Horst Blüthmann,Jeevajothie Karthigasan,Daniel A. Kirschner,Eva Sabine Wintergerst,Klaus-Armin Nave,Jürgen Zielasek,Klaus V. Toyka,Hans-Peter Lipp,Melitta Schachner +13 more
TL;DR: Observations suggest that MAG participates in the formation of the periaxonal cytoplasmic collar of oligodendrocytes and in the recognition between oligodendedrocyte processes and axons.