Helen R. Fryer

TL;DR: It is shown that virus evolution and trafficking between tissue compartments continues in patients with undetectable levels of virus in their bloodstream, revealing that HIV-1 can continue to replicate and replenish the viral reservoir despite potent antiretroviral therapy.

TL;DR: In this article , the authors demonstrate substantial evasion of neutralization by Omicron BA.1 and BA.2 variants in vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2 and mRNA-1273.529.

TL;DR: In this article , the authors investigated anti-spike IgG antibody responses and correlates of protection after second doses of ChAdOx1 or BNT162b2 vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

TL;DR: A novel in vivo experimental method and accompanying mathematical analysis provide greater insight into the relative fitness, both within the host and between hosts, of two different influenza virus strains compared to more traditional methods that infect ferrets with only pure populations of viruses.

TL;DR: A mathematical model of within-host evolution of escape mutants, transmission of these variants between hosts and subsequent reversion in new hosts is presented and used to explain why some escape mutants appear to have stable prevalence whilst others are spreading through the population.