K
Kirsty Danielson
Researcher at University of Otago
Publications - 35
Citations - 1455
Kirsty Danielson is an academic researcher from University of Otago. The author has contributed to research in topics: Extracellular RNA & Heart failure. The author has an hindex of 16, co-authored 33 publications receiving 1085 citations. Previous affiliations of Kirsty Danielson include Wellington Management Company & Victoria University of Wellington.
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Journal ArticleDOI
exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids
Oscar Murillo,William Thistlethwaite,Joel Rozowsky,Sai Lakshmi Subramanian,Rocco Lucero,Neethu Shah,Andrew R. Jackson,Srimeenakshi Srinivasan,Allen Chung,Allen Chung,Clara D. Laurent,Robert R. Kitchen,Timur R. Galeev,Jonathan Warrell,James A. Diao,James A. Diao,Joshua A. Welsh,Kristina Hanspers,Anders Riutta,Sebastian Burgstaller-Muehlbacher,Ravi V. Shah,Ashish Yeri,Lisa M. Miller Jenkins,Mehmet Eren Ahsen,Carlos Cordon-Cardo,Navneet Dogra,Navneet Dogra,Stacey M. Gifford,Joshua T. Smith,Gustavo Stolovitzky,Gustavo Stolovitzky,Ashutosh K. Tewari,Benjamin H. Wunsch,Kamlesh K Yadav,Kirsty Danielson,Justyna Filant,Courtney Moeller,Parham Nejad,Anu Paul,Bridget Simonson,David K. Wong,David K. Wong,Xuan Zhang,Leonora Balaj,Roopali Gandhi,Anil K. Sood,Roger P. Alexander,Liang Wang,Chunlei Wu,David T.W. Wong,David J. Galas,Kendall Van Keuren-Jensen,Tushar Patel,Jennifer Jones,Saumya Das,Kei-Hoi Cheung,Alexander R. Pico,Andrew I. Su,Robert L. Raffai,Robert L. Raffai,Louise C. Laurent,Matthew E. Roth,Mark Gerstein,Aleksandar Milosavljevic +63 more
TL;DR: A model with six exRNA cargo types, each detectable in multiple biofluids, is presented and tools for deconvolution and analysis of user-provided case-control studies are provided to enable wide application of this model.
Journal ArticleDOI
Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation
Srimeenakshi Srinivasan,Ashish Yeri,Pike See Cheah,Pike See Cheah,Allen Chung,Kirsty Danielson,Peter De Hoff,Justyna Filant,Clara D. Laurent,Clara D. Laurent,Lucie D. Laurent,Rogan Magee,Courtney Moeller,Venkatesh L. Murthy,Parham Nejad,Anu Paul,Isidore Rigoutsos,Rodosthenis S. Rodosthenous,Ravi V. Shah,Bridget Simonson,Cuong To,David K. Wong,Irene K. Yan,Xuan Zhang,Leonora Balaj,Xandra O. Breakefield,George G. Daaboul,Roopali Gandhi,Jodi Lapidus,Eric Londin,Tushar Patel,Robert L. Raffai,Anil K. Sood,Roger P. Alexander,Saumya Das,Louise C. Laurent +35 more
TL;DR: An interactive web-based application (miRDaR) was developed to help investigators select the optimal exRNA isolation method for their studies and returns a ranked list of ex RNA isolation methods prioritized by complexity, expression level, and reproducibility.
Journal ArticleDOI
Diverse human extracellular RNAs are widely detected in human plasma
Jane E. Freedman,Mark Gerstein,Eric Mick,Joel Rozowsky,Daniel Levy,Robert R. Kitchen,Saumya Das,Ravi V. Shah,Kirsty Danielson,Lea M. Beaulieu,Fabio C. P. Navarro,Yaoyu E. Wang,Timur R. Galeev,Alex Holman,Raymond Y. Kwong,Venkatesh L. Murthy,Selim E. Tanriverdi,Milka Koupenova-Zamor,Ekaterina Mikhalev,Kahraman Tanriverdi +19 more
TL;DR: Over a thousand human extracellular RNAs including microRNAs, piwi-interacting RNA (piRNA), and small nucleolar RNAs are identified by analysing sequencing data from plasma-derived RNA from 40 individuals to demonstrate the broad and consistent detection of diverse classes of circulating non-cellular small-RNAs from a large population.
Journal ArticleDOI
Circulating MicroRNA-30d is Associated with Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study
Yonathan F. Melman,Ravi V. Shah,Ravi V. Shah,Kirsty Danielson,Junjie Xiao,Bridget Simonson,Andreas S. Barth,Khalid Chakir,Gregory D. Lewis,Zachary R Lavender,Quynh A. Truong,André G. Kléber,Ranendra K. Das,Anthony Rosenzweig,Yaoyu E. Wang,David A. Kass,Jagmeet P. Singh,Saumya Das +17 more
TL;DR: MiR-30d increase in cardiomyocytes correlates with areas of increased wall stress in HFDYS and is protective against deleterious tumor necrosis factor signaling and is associated with response to CRT in H FDYS in this translational pilot study.
Journal ArticleDOI
miRNA Signatures of Insulin Resistance in Obesity.
Angela Jones,Kirsty Danielson,Miles C. Benton,Miles C. Benton,Olivia Ziegler,Ravi V. Shah,Richard S. Stubbs,Saumya Das,Donia Macartney-Coxson +8 more
TL;DR: This study investigated plasma miRNAs in insulin resistance phenotypes in obesity by studying their role in obesity-related diseases and found associations with fasting insulin resistance and type 2 diabetes.