L
Lena M. Napolitano
Researcher at University of Michigan
Publications - 314
Citations - 20992
Lena M. Napolitano is an academic researcher from University of Michigan. The author has contributed to research in topics: ARDS & Intensive care. The author has an hindex of 62, co-authored 297 publications receiving 17573 citations. Previous affiliations of Lena M. Napolitano include United States Department of Veterans Affairs & Veterans Health Administration.
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Journal ArticleDOI
Current status of blood component therapy in surgical critical care.
TL;DR: An increased understanding of the pathophysiology of the anemia associated with critical care, related to the inflammatory response, downregulation of erythropoietin, and lack of iron availability due to macrophage sequestration is gained.
Journal ArticleDOI
Inappropriate initial antibiotic treatment for complicated skin and soft tissue infections in hospitalized patients: incidence and associated factors.
Benjamin A. Lipsky,Benjamin A. Lipsky,Lena M. Napolitano,Gregory J. Moran,Lien Vo,Susan C. Nicholson,Myoung Kim +6 more
TL;DR: Investigation of incidence of, and risk factors associated with, inappropriate initial antibiotic treatment (IIAT) in hospitalized adults treated with intravenous antibiotic(s) for complicated skin and soft tissue infections (cSSTIs) found IIAT for cS STIs was relatively frequent in these hospitalized patients, especially those with selected risk factors.
Journal ArticleDOI
Pharmacokinetics of oseltamivir and oseltamivir carboxylate in critically ill patients receiving continuous venovenous hemodialysis and/or extracorporeal membrane oxygenation.
Rachel F. Eyler,Michael Heung,Melissa Pleva,Kevin M. Sowinski,Pauline K. Park,Lena M. Napolitano,Bruce A. Mueller +6 more
TL;DR: To investigate oseltamivir and oselTAMivir carboxylate pharmacokinetics in critically ill patients who were receiving continuous venovenous hemodialysis and extracorporeal membrane oxygenation.
Journal ArticleDOI
Hepcidin in Trauma: Linking Injury, Inflammation, and Anemia
TL;DR: Hepcidin levels rise to extremely high but variable levels after trauma and are positively correlated with injury severity measured by ISS and duration of anemia and negatively correlated with hypoxia.
Journal ArticleDOI
A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway
Massimo Sartelli,Yoram Kluger,Luca Ansaloni,Jean Carlet,Adrian Brink,Adrian Brink,Timothy Craig Hardcastle,Ashish Khanna,Alain Chicom-Mefire,Jesús Rodríguez-Baño,Dilip Nathwani,Marc Mendelson,Richard R. Watkins,Céline Pulcini,Bojana Beović,Addison K. May,Kamal M.F. Itani,John E. Mazuski,Donald E. Fry,Donald E. Fry,Federico Coccolini,Kemal Rasxa,Philippe Montravers,Christian Eckmann,Lilian M. Abbo,Lilian M. Abbo,Salisu Abubakar,Fikri M. Abu-Zidan,A R K Adesunkanmi,Majdi N. Al-Hasan,Asma Althani,Jorge Eduardo Alvarenga Ticas,Shamshul Ansari,Shamshul Ansari,Rashid Ansumana,André Ricardo Araujo da Silva,Goran Augustin,Miklosh Bala,Zsolt J. Balogh,Oussema Baraket,Matteo Bassetti,Giovanni Bellanova,Marcelo A. Beltrán,Ofir Ben-Ishay,Walter L. Biffl,Marja A. Boermeester,Stephen M. Brecher,Juan Bueno,Miguel Caínzos,Kelly A. Cairns,Adrián Camacho-Ortiz,Marco Ceresoli,Sujith J Chandy,Jill R. Cherry-Bukowiec,Roberto Cirocchi,Elif Colak,Antonio Corcione,Oliver A. Cornely,Francesco Cortese,Yunfeng Cui,Daniel Curcio,Dimitris Damaskos,Koray Dasx,Samir Delibegovic,Zaza Demetrashvili,Belinda De Simone,Hamilton Petry de Souza,Jan J. De Waele,Sameer Dhingra,Jose J. Diaz,Isidoro Di Carlo,Francesco Di Marzo,Salomone Di Saverio,Agron Dogjani,Gereltuya Dorj,Laurent Dortet,Therese M. Duane,Hervé Dupont,Valery N. Egiev,Hani O. Eid,Mutasim M. Elmangory,Hany E. Marei,Mushira Enani,Kevin Escandón-Vargas,Mario Paulo Faro,Paula Ferrada,Domitilla Foghetti,Esteban Foianini,Gustavo Pereira Fraga,Sabrina Frattima,Chinmay Gandhi,Gianni Gattuso,Eleni Giamarellou,Wagih Ghnnam,George Gkiokas,Massimo Girardis,Debbie A. Goff,Carlos Augusto Gomes,Harumi Gomi,Rosio Isabel Guerra Gronerth,Xavier Guirao,Manuel Guzman-Blanco,Mainul Haque,Andreas Hecker,Markus Hell,Torsten Herzog,Lauri A. Hicks,Reinhold Kafka-Ritsch,Lillian S. Kao,Souha S. Kanj,Lewis J. Kaplan,Garima Kapoor,Aleksandar Karamarkovic,Jeffry L. Kashuk,Jakub Kenig,Faryal Khamis,Vladimir Khokha,Ronald Kiguba,Andrew W. Kirkpatrick,Hartwig Kørner,Kaoru Koike,Kenneth Y.Y. Kok,Kateryna Kon,Victor Y. Kong,Kenji Inaba,Orestis Ioannidis,Arda Isik,Katia Iskandar,Maurizio Labbate,Francesco M. Labricciosa,Katrien Lagrou,Leonel Lagunes,Rifat Latifi,Kostas Lasithiotakis,Ramanan Laxminarayan,Jae Gil Lee,Marc Leone,Ari Leppäniemi,Yousheng Li,Stephen Y. Liang,Kui Hin Liau,Andrey Litvin,Tonny Loho,Warren Lowman,Gustavo M. Machain,Ronald V. Maier,Ramiro Manzano-Nunez,Athanasios Marinis,Cristina Marmorale,Ignacio Martin-Loeches,Sanjay Marwah,Emilio Maseda,Michael McFarlane,Renato Bessa Melo,Maria Rita Melotti,Ziad A. Memish,Dominik Mertz,Cristian Mesina,Francesco Menichetti,Shyam Kumar Mishra,Giulia Montori,Ernest E. Moore,Frederick A. Moore,Noel Naidoo,Lena M. Napolitano,Ionut Negoi,David P. Nicolau,Ioannis Nikolopoulos,Carl Erik Nord,Richard Ofori-Asenso,Iyiade Olaoye,Abdelkarim H. Omari,Carlos A. Ordoñez,Mouaqit Ouadii,Abdoul Salam Ouedraogo,Leonardo Pagani,José Artur Paiva,José Gustavo Parreira,Francesco Pata,Jorge Pereira,Nuno R. Pereira,Nicola Petrosillo,Edoardo Picetti,Tadeja Pintar,Alfredo Ponce-de-León,Zagorka Popovski,Garyphallia Poulakou,Jacobus Preller,Adrián Puello Guerrero,Guntars Pupelis,Martha Quiodettis,Timothy M. Rawson,Martin Reichert,Konrad Reinhart,Miran Rems,Jordi Rello,Sandro Rizoli,Jason A. Roberts,Ines Rubio-Perez,Etienne Ruppe,Boris Sakakushev,Ibrahima Sall,Hossein Samadi Kafil,James M. Sanders,Norio Sato,Robert G. Sawyer,Thomas M. Scalea,Rodolfo Scibé,Luigia Scudeller,Helmut Alfredo Segovia Lohse,Gabriele Sganga,Nusrat Shafiq,Jay N Shah,Patrizia Spigaglia,Shanoo Suroowan,Constantinos Tsioutis,Costi D. Sifri,Boonying Siribumrungwong,Michael Sugrue,Peep Talving,Boun Kim Tan,Antonio Tarasconi,Carlo Tascini,Jonathan Tilsed,Jean-François Timsit,Mario Tumbarello,Ngo Tat Trung,Jan Ulrych,Selman Uranues,George C. Velmahos,András Vereczkei,Pierluigi Viale,Jordi Vila Estape,Claudio Viscoli,Florian M.E. Wagenlehner,Brian J. Wright,Yonghong Xiao,Kuo Ching Yuan,Sanoop K. Zachariah,Jean-Ralph Zahar,Paulo Mergulhão,Fausto Catena +241 more
TL;DR: This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use of antibiotic agents and antifungal agents in hospitals worldwide especially focusing on surgical infections.