M
María Berdasco
Researcher at University of Oviedo
Publications - 69
Citations - 5357
María Berdasco is an academic researcher from University of Oviedo. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 31, co-authored 66 publications receiving 4528 citations. Previous affiliations of María Berdasco include Carlos III Health Institute & Catalan Institution for Research and Advanced Studies.
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Journal ArticleDOI
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
Biola M. Javierre,Agustín F. Fernández,Julia Richter,Fatima Al-Shahrour,J. Ignacio Martin-Subero,Javier Rodríguez-Ubreva,María Berdasco,Mario F. Fraga,Terrance P. O'Hanlon,Lisa G. Rider,Filipe V. Jacinto,F. Javier López-Longo,Joaquín Dopazo,Marta Forn,Miguel A. Peinado,Luis Carreño,Amr H. Sawalha,John B. Harley,Reiner Siebert,Manel Esteller,Frederick W. Miller,Esteban Ballestar +21 more
TL;DR: The findings not only identify potentially relevant DNA methylation markers for the clinical characterization of SLE patients but also support the notion that epigenetic changes may be critical in the clinical manifestations of autoimmune disease.
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Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
María Berdasco,Manel Esteller +1 more
TL;DR: An overview of how epigenetic factors, including genomic DNA methylation, histone modifications, and microRNA regulation, contribute to normal development, paying special attention to their role in regulating tissue-specific genes, is provided.
Journal ArticleDOI
A DNA methylation fingerprint of 1628 human samples
Augustin F. Fernandez,Yassen Assenov,José I. Martín-Subero,Balázs Bálint,Reiner Siebert,Hiroaki Taniguchi,Hiroyuki Yamamoto,Manuel Hidalgo,Manuel Hidalgo,Aik Choon Tan,Oliver Galm,Isidre Ferrer,Montse Sanchez-Cespedes,Alberto Villanueva,Javier Carmona,Jose V. Sanchez-Mut,María Berdasco,Victor Moreno,Gabriel Capellá,David Monk,Esteban Ballestar,Santiago Ropero,Ramon Martinez,Marta Sanchez-Carbayo,Felipe Prosper,Xabier Agirre,Mario F. Fraga,Mario F. Fraga,Osvaldo Graña,Luis A. Pérez-Jurado,Jaume Mora,Susana Puig,Jaime Prat,Lina Badimon,Annibale Alessandro Puca,Stephen J. Meltzer,Thomas Lengauer,John Bridgewater,Christoph Bock,Manel Esteller +39 more
TL;DR: The DNA methylation patterns identified across the largest spectrum of samples, tissues, and diseases reported to date constitute a baseline for developing higher-resolutionDNA methylation maps and provide important clues concerning the contribution of CpG methylation to tissue identity and its changes in the most prevalent human diseases.
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A Role for RNAi in the Selective Correction of DNA Methylation Defects
Felipe Karam Teixeira,Fabiana Heredia,Alexis Sarazin,François Roudier,François Roudier,Martine Boccara,Martine Boccara,Constance Ciaudo,Constance Ciaudo,Corinne Cruaud,Julie Poulain,María Berdasco,Mario F. Fraga,Olivier Voinnet,Patrick Wincker,Manel Esteller,Vincent Colot,Vincent Colot +17 more
TL;DR: An important role for RNAi is suggested in protecting genomes against long-term epigenetic defects by demonstrating the existence of an efficient mechanism that protects against transgenerational loss of DNA methylation in Arabidopsis.
Journal ArticleDOI
Clinical epigenetics: seizing opportunities for translation.
María Berdasco,Manel Esteller +1 more
TL;DR: Beyond helping to understand disease biology, clinical epigenetics is being incorporated into patient management in oncology, as well as being explored for clinical applicability for other human pathologies such as neurological and infectious diseases and immune system disorders.