M
Mario Masellis
Researcher at Sunnybrook Health Sciences Centre
Publications - 290
Citations - 9815
Mario Masellis is an academic researcher from Sunnybrook Health Sciences Centre. The author has contributed to research in topics: Frontotemporal dementia & Medicine. The author has an hindex of 42, co-authored 212 publications receiving 6662 citations. Previous affiliations of Mario Masellis include Sunnybrook Research Institute & Centre for Addiction and Mental Health.
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Journal ArticleDOI
Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia
Kamen A. Tsvetanov,Kamen A. Tsvetanov,Stefano Gazzina,Stefano Gazzina,P. Simon Jones,John C. van Swieten,Barbara Borroni,Raquel Sánchez-Valle,Fermin Moreno,Robert Laforce,Caroline Graff,Caroline Graff,Matthis Synofzik,Matthis Synofzik,Daniela Galimberti,Daniela Galimberti,Mario Masellis,Maria Carmela Tartaglia,Elizabeth Finger,Rik Vandenberghe,Alexandre de Mendonça,Fabrizio Tagliavini,Isabel Santana,Simon Ducharme,Simon Ducharme,Christopher C Butler,Alexander Gerhard,Alexander Gerhard,A. Danek,Johannes Levin,Markus Otto,Giovanni B. Frisoni,Roberta Ghidoni,Sandro Sorbi,Jonathan D. Rohrer,James B. Rowe,James B. Rowe,Genfi Genetic Ftd Initiative +37 more
TL;DR: The presymptomatic phase of neurodegenerative disease can last many years, with sustained cognitive function despite progressive atrophy, in familial frontotemporal dementia (FTD).
Journal ArticleDOI
Orthostatic hypotension, cerebral hypoperfusion, and visuospatial deficits in Lewy body disorders.
Andrew D. Robertson,Michelle A. Messner,Zahra Shirzadi,Galit Kleiner-Fisman,Joyce Lee,Julia Hopyan,Anthony E. Lang,Sandra E. Black,Bradley J. MacIntosh,Mario Masellis +9 more
TL;DR: Findings provide new insight that regional cerebral hypoperfusion is related to orthostatic hypotension, and may be involved in domain-specific cognitive deficits in Lewy body disorders.
Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies
Yi Su,Shaney Flores,Guoqiao Wang,Russ C. Hornbeck,Benjamin Speidel,Nelly Joseph-Mathurin,Andrei G. Vlassenko,Brian A. Gordon,Robert A. Koeppe,William E. Klunk,R. Jack Clifford,Martin R. Farlow,Stephen Salloway,Barbara J. Snider,Sarah B. Berman,Erik D. Roberson,Jared Broschi,Ivonne Jimenez-Velazques,Christopher H. van Dyck,Douglas Galasko,Shauna H. Yuan,Suman Jayadev,Lawrence S. Honig,Serge Gauthier,Ging-Yuek Robin Hsiung,Mario Masellis,William S. Brooks,Michael J. Fulham,Roger Clarnette,Colin L. Masters,David Wallon,Didier Hannequin,Bruno Dubois,Jérémie Pariente,Raquel Sánchez-Valle,Catherine J. Mummery,John M. Ringman,Michel Bottlaender,Gregory Klein,Smiljana Milosavljevic-Ristic,Eric McDade,Chengjie Xiong,John C. Morris,Randall J. Bateman,Tammie L.S. Benzinger +44 more
TL;DR: In this article, a direct comparison of Pittsburgh compound B-based and florbetapir-based amyloid imaging in the same participants from two independent cohorts using a crossover design is presented.
Journal ArticleDOI
Brain degeneration in Parkinson's disease patients with cognitive decline: a coordinate-based meta-analysis.
Alexander Mihaescu,Mario Masellis,Ariel Graff-Guerrero,Jinhee Kim,Marion Criaud,Sang Soo Cho,Christine Ghadery,Mikaeel Valli,Antonio P. Strafella +8 more
TL;DR: The results found both a spectrum of increasing brain atrophy in PD cognitive impairment and supports the existence of sub-typing in PD-MCI.
Journal ArticleDOI
White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study
Carole H. Sudre,Carole H. Sudre,Carole H. Sudre,Martina Bocchetta,Carolin Heller,Rhian S Convery,Mollie Neason,Katrina M. Moore,David M. Cash,David M. Cash,David L. Thomas,Ione O.C. Woollacott,Martha S. Foiani,Amanda Heslegrave,Rachelle Shafei,Caroline V. Greaves,John C. van Swieten,Fermin Moreno,Raquel Sánchez-Valle,Barbara Borroni,Robert Laforce,Mario Masellis,Maria Carmela Tartaglia,Caroline Graff,Daniela Galimberti,James B. Rowe,Elizabeth Finger,Matthis Synofzik,Rik Vandenberghe,Alexandre de Mendonça,Fabrizio Tagliavini,Isabel Santana,Simon Ducharme,Christopher C Butler,Alexander Gerhard,Johannes Levin,Adrian Danek,Giovanni B. Frisoni,Sandro Sorbi,Markus Otto,Henrik Zetterberg,Sebastien Ourselin,M. Jorge Cardoso,M. Jorge Cardoso,M. Jorge Cardoso,Jonathan D. Rohrer,Martin N. Rossor,Jason D. Warren,Nick C. Fox,Rita Guerreiro,Jose Bras,Jennifer M. Nicholas,Simon Mead,Lize C. Jiskoot,Lieke H.H. Meeter,Jessica L. Panman,Janne M. Papma,Rick van Minkelen,Y.A.L. Pijnenburg,Myriam Barandiaran,Begoña Indakoetxea,Alazne Gabilondo,Mikel Tainta,Maria de Arriba,Ana Gorostidi,Miren Zulaica,Jorge Villanua,Zigor Diaz,Sergi Borrego-Écija,Jaume Olives,Albert Lladó,Mircea Balasa,Anna Antonell,Núria Bargalló,Enrico Premi,Maura Cosseddu,Stefano Gazzina,Alessandro Padovani,Roberto Gasparotti,Silvana Archetti,Sandra E. Black,Sara Mitchell,Ekaterina Rogaeva,Morris Freedman,Ron Keren,David F. Tang-Wai,Linn Öijerstedt,Christin Andersson,Vesna Jelic,Håkan Thonberg,Andrea Arighi,Chiara Fenoglio,Elio Scarpini,Giorgio G. Fumagalli,Thomas E. Cope,Carolyn Timberlake,Timothy Rittman,Christen Shoesmith,Robart Bartha,Rosa Rademakers,Carlo Wilke,Hans-Otto Karnarth,Benjamin Bender,Rose Bruffaerts,Philip Vandamme,Mathieu Vandenbulcke,C. Ferreira,Gabriel Miltenberger,Carolina Maruta,Ana Verdelho,Sónia Afonso,Ricardo Taipa,Paola Caroppo,Giuseppe Di Fede,Giorgio Giaccone,Sara Prioni,Veronica Redaelli,Giacomina Rossi,Pietro Tiraboschi,Diana Duro,Maria Rosário Almeida,Miguel Castelo-Branco,Maria João Leitão,Miguel Tábuas-Pereira,Beatriz Santiago,Serge Gauthier,Pedro Rosa-Neto,Michele Veldsman,Toby Flanagan,Catharina Prix,Tobias Hoegen,Elisabeth Wlasich,Sandra V. Loosli,Sonja Schönecker,Elisa Semler,Sarah Anderl-Straub,Luisa Benussi,Giuliano Binetti,Roberta Ghidoni,Michela Pievani,Gemma Lombardi,Benedetta Nacmias,Camilla Ferrari,Valentina Bessi +143 more
TL;DR: Investigation of longitudinal change in WMH and the associations of WMH burden with grey matter (GM) loss, markers of neurodegeneration and cognitive function in GRN mutation carriers revealed that WMH load was higher in both symptomatic and presymptomatic groups compared with controls and this load increased over time.