M
Mark Fiers
Researcher at Katholieke Universiteit Leuven
Publications - 64
Citations - 9370
Mark Fiers is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 30, co-authored 55 publications receiving 7576 citations. Previous affiliations of Mark Fiers include Flanders Institute for Biotechnology & Wageningen University and Research Centre.
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Journal ArticleDOI
Genome sequence and analysis of the tuber crop potato.
Xun Xu,Shengkai Pan,Shifeng Cheng,Bo Zhang,Mu D,Peixiang Ni,Gengyun Zhang,Shuang Yang,Ruiqiang Li,Jun Wang,Gisella Orjeda,Frank Guzman,Torres M,Roberto Lozano,Olga Ponce,Diana Martinez,De la Cruz G,Chakrabarti Sk,Patil Vu,Konstantin G. Skryabin,Boris B. Kuznetsov,Nikolai V. Ravin,Tatjana V. Kolganova,Alexey V. Beletsky,Andrey V. Mardanov,Di Genova A,Dan Bolser,David M. A. Martin,Li G,Yang Y,Hanhui Kuang,Hu Q,Xiong X,Gerard J. Bishop,Boris Sagredo,Nilo Mejía,Zagorski W,Robert Gromadka,Jan Gawor,Pawel Szczesny,Sanwen Huang,Zhang Z,Liang C,He J,Li Y,He Y,Xu J,Youjun Zhang,Xie B,Du Y,Qu D,Merideth Bonierbale,Marc Ghislain,Herrera Mdel R,Giovanni Giuliano,Marco Pietrella,Gaetano Perrotta,Paolo Facella,O'Brien K,Sergio Enrique Feingold,Barreiro Le,Massa Ga,Luis Aníbal Diambra,Brett R Whitty,Brieanne Vaillancourt,Lin H,Alicia N. Massa,Geoffroy M,Lundback S,Dean DellaPenna,Buell Cr,Sanjeev Kumar Sharma,David Marshall,Robbie Waugh,Glenn J. Bryan,Destefanis M,Istvan Nagy,Dan Milbourne,Susan Thomson,Mark Fiers,Jeanne M. E. Jacobs,Kåre Lehmann Nielsen,Mads Sønderkær,Marina Iovene,Giovana Augusta Torres,Jiming Jiang,Richard E. Veilleux,Christian W. B. Bachem,de Boer J,Theo Borm,Bjorn Kloosterman,van Eck H,Erwin Datema,Hekkert Bt,Aska Goverse,van Ham Rc,Richard G. F. Visser +96 more
TL;DR: The potato genome sequence provides a platform for genetic improvement of this vital crop and predicts 39,031 protein-coding genes and presents evidence for at least two genome duplication events indicative of a palaeopolyploid origin.
Journal ArticleDOI
Complete genome sequence of Lactobacillus plantarum WCFS1
Michiel Kleerebezem,Jos Boekhorst,Richard van Kranenburg,Douwe Molenaar,Oscar P. Kuipers,R.J. Leer,Renato Tarchini,Sander Peters,Hans Sandbrink,Mark Fiers,Willem J. Stiekema,René Klein Lankhorst,Peter A. Bron,Sally M. Hoffer,Masja Nierop Groot,Robert Kerkhoven,Maaike C. de Vries,Björn M. Ursing,Willem M. de Vos,Roland J. Siezen +19 more
TL;DR: The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes, suggesting that these genes form a lifestyle adaptation region in the chromosome.
Journal ArticleDOI
iRegulon: from a gene list to a gene regulatory network using large motif and track collections.
Rekin's Janky,Annelien Verfaillie,Hana Imrichova,Bram Van de Sande,Laura Standaert,Valerie Christiaens,Gert Hulselmans,Koen Herten,Marina Naval Sanchez,Delphine Potier,Dmitry Svetlichnyy,Zeynep Kalender Atak,Mark Fiers,Jean-Christophe Marine,Stein Aerts +14 more
TL;DR: Over-activate p53 in breast cancer cells, followed by RNA-seq and ChIP-seq, and could identify an extensive up-regulated network controlled directly by p53 and a repressive network with no indication of direct p53 regulation but rather an indirect effect via E2F and NFY are mapped.
Journal ArticleDOI
Biochar induced soil microbial community change: Implications for biogeochemical cycling of carbon, nitrogen and phosphorus
Craig Anderson,Leo M. Condron,Timothy J. Clough,Mark Fiers,Alison Stewart,Robert A. Hill,Robert R. Sherlock +6 more
TL;DR: In this article, a controlled pot experiment was designed to investigate temporal changes in soil microbial ecology and physicochemical parameters in the presence and absence of biochar in both the rhizosphere and bulk soil using TRFLP coupled with a 454 new generation sequencing database.
Journal ArticleDOI
A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain
Kristofer Davie,Janssens J,Duygu Koldere,De Waegeneer M,Uli Pech,Łukasz Kreft,Sara Aibar,Samira Makhzami,Valerie Christiaens,Carmen Bravo González-Blas,Suresh Poovathingal,Gert Hulselmans,Katina I. Spanier,Thomas Moerman,Bram Vanspauwen,Sarah Geurs,Thierry Voet,Jeroen Lammertyn,Bernard Thienpont,Sha Liu,Nikos Konstantinides,Mark Fiers,Patrik Verstreken,Stein Aerts +23 more
TL;DR: A single-cell transcriptome atlas of the entire adult Drosophila melanogaster brain sampled across its lifespan is presented, allowing comprehensive exploration of all transcriptional states of an entire aging brain.