M
Michael Bachmann
Researcher at Helmholtz-Zentrum Dresden-Rossendorf
Publications - 402
Citations - 16252
Michael Bachmann is an academic researcher from Helmholtz-Zentrum Dresden-Rossendorf. The author has contributed to research in topics: Antigen & Chimeric antigen receptor. The author has an hindex of 63, co-authored 360 publications receiving 14388 citations. Previous affiliations of Michael Bachmann include ACADIA Pharmaceuticals Inc. & University of Southern California.
Papers
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Journal ArticleDOI
Detection of autoantibodies to tumour-associated antigens in sera of patients with systemic autoimmunity using a novel protein microblot array.
Ulrich Canzler,Holger Bartsch,S. Ulitzsch,Biji T. Kurien,Yaser Dorri,Scofield Rh,K. Grossmann,W. Lehmann,Christian Pilarsky,Axel Denz,Robert Grützmann,Karsten Conrad,Marc Schmitz,Ernst Peter Rieber,W. Distler,Michael Bachmann +15 more
TL;DR: Using this novel assay, the frequency of autoantibodies to the selected tumour‐associated antigens is increased between 2‐ and 14‐fold in patients with systemic autoimmunity compared with an age‐matched control group.
Journal ArticleDOI
Cytotoxic response of human regulatory T cells upon T-cell receptor-mediated activation: a matter of purity.
Stefanie Koristka,Marc Cartellieri,Claudia Arndt,Anja Feldmann,Anja Feldmann,Katrin Töpfer,Irene Michalk,Achim Temme,G. Ehninger,Michael Bachmann +9 more
TL;DR: Rec recombinant bispecific antibodies (bsAb) were applied for antigen-specific redirection of polyclonal human T cells as surrogate for T-cell receptor (TCR)-mediated stimulation and have been proven to be highly effective in inducing the lytic capacity of both CD4+ and CD8+ Teffs.
Posted ContentDOI
COVID-19 is associated with relative ADAMTS13 deficiency and VWF multimer formation resembling TTP
Adrian Doevelaar,Martin Bachmann,Bodo Hoelzer,Felix S. Seibert,Benjamin S Rohn,Frederic Bauer,Oliver Witzke,Ulf Dittmer,Michael Bachmann,Serap Yilmaz,Rita Dittmer,Sonja Schneppenheim,Nina Babel,Ulrich Budde,Timm H. Westhoff +14 more
TL;DR: COVID-19 is associated with a substantial increase in VWF levels, which can exceed the ADAMTS13 processing capacity resulting in the formation of large VWF multimers identical to TTP.
Patent
Method for protecting a vehicle with an automatic parking brake
TL;DR: In this paper, a method for holding a vehicle at a standstill includes a first phase in which the brake pressure at the wheel brakes is retained so that the vehicle is held automatically by the service brake, and the braking force is then transferred to a parking brake so that in a second phase the vehicle was held solely by the parking brake.
Journal ArticleDOI
An altered intracellular distribution of the autoantigen La/SS-B when translated from a La mRNA isoform.
Daniel Grölz,Michael Bachmann +1 more
TL;DR: Transcription of the gene encoding for the nuclear autoantigen La resulted in La mRNA isoforms that encoded for three open reading frames upstream of the La protein reading frame and the translational efficiency was about 14% of exon 1 La mRNA using rabbit reticulolysate for in vitro translation.