M
Michael Bachmann
Researcher at Helmholtz-Zentrum Dresden-Rossendorf
Publications - 402
Citations - 16252
Michael Bachmann is an academic researcher from Helmholtz-Zentrum Dresden-Rossendorf. The author has contributed to research in topics: Antigen & Chimeric antigen receptor. The author has an hindex of 63, co-authored 360 publications receiving 14388 citations. Previous affiliations of Michael Bachmann include ACADIA Pharmaceuticals Inc. & University of Southern California.
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Journal ArticleDOI
D-GPCR: a novel putative G protein-coupled receptor overexpressed in prostate cancer and prostate.
Bernd Weigle,Susanne Fuessel,Reinhard Ebner,Achim Temme,Marc Schmitz,Sandra Schwind,Andrea Kiessling,Michael A. Rieger,Axel Meye,Michael Bachmann,Manfred P. Wirth,E. Peter Rieber +11 more
TL;DR: The novel protein D-GPCR that is selectively overexpressed in human prostate cancer and prostate and belongs to the subfamily of odorant-like orphan G protein-coupled receptors is identified and its utility as a novel target in immunotherapy of prostate cancer is identified.
Journal ArticleDOI
UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells
Claudia Arndt,Liliana R. Loureiro,Anja Feldmann,Justyna Jureczek,Justyna Jureczek,Ralf Bergmann,Ralf Bergmann,Domokos Máthé,Nikolett Hegedüs,Nicole Berndt,Stefanie Koristka,Nicola Mitwasi,Frederick Fasslrinner,Chris Lamprecht,Alexandra Kegler,Alexandra Kegler,Anja Hoffmann,Tabea Bartsch,Ayşe Sedef Köseer,Gary F. Egan,Marc Schmitz,Marc Schmitz,Marc Schmitz,Václav Hořejší,Mechthild Krause,Anna Dubrovska,Michael Bachmann +26 more
TL;DR: The obtained data underline that the UniCAR system is able to overcome radioresistance and represents an attractive technology for the development of combined radioimmunotherapeutic approaches that might improve the outcome of patients with metastatic radioresistant tumor diseases.
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Evidence for a direct interaction of Rev protein with nuclear envelope mRNA - translocation system
Karin Pfeifer,Barbara E. Weiler,Durdica Ugarkovic,Michael Bachmann,Heinz C. Schröder,Werner E.G. Müller +5 more
TL;DR: Evidence is presented that Rev down-regulates the NTPase-driven transport of mRNA lacking the RRE, most likely via binding to the mRNA carrier within the envelope, in contrast to the efflux of RRE-free RNA.
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D-TMPP: a novel androgen-regulated gene preferentially expressed in prostate and prostate cancer that is the first characterized member of an eukaryotic gene family.
Andrea Kiessling,Bernd Weigle,Susanne Fuessel,Reinhard Ebner,Axel Meye,Michael A. Rieger,Marc Schmitz,Achim Temme,Michael Bachmann,Manfred P. Wirth,E. Peter Rieber +10 more
TL;DR: The novel gene Dresden‐transmembrane protein of the prostate (D‐TMPP) is identified that is overexpressed in human prostate and prostate cancer.
Journal ArticleDOI
Functional DNA Delivery Enabled by Lipid-Modified Charge-Altering Releasable Transporters (CARTs).
Nancy L. Benner,Katherine E. Near,Michael Bachmann,Christopher H. Contag,Robert M. Waymouth,Paul A. Wender +5 more
TL;DR: CART-pDNA complexes represent a new DNA delivery system for research and clinical applications and shows enhanced performance relative to the commercial transfection agent Lipofectamine 2000 (L2000).