M
Michael Bachmann
Researcher at Helmholtz-Zentrum Dresden-Rossendorf
Publications - 402
Citations - 16252
Michael Bachmann is an academic researcher from Helmholtz-Zentrum Dresden-Rossendorf. The author has contributed to research in topics: Antigen & Chimeric antigen receptor. The author has an hindex of 63, co-authored 360 publications receiving 14388 citations. Previous affiliations of Michael Bachmann include ACADIA Pharmaceuticals Inc. & University of Southern California.
Papers
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Journal ArticleDOI
Engineered extracellular matrix components do not alter the immunomodulatory properties of mesenchymal stromal cells in vitro.
Rebekka Wehner,Christina Taubert,Tanja Mende,Christian Gaebler,Ana Valeria Gouveia de Andrade,Martin Bornhäuser,Carsten Werner,Torsten Tonn,Torsten Tonn,Knut Schäkel,Michael Bachmann,Marc Schmitz +11 more
TL;DR: Fibronectin, fibrillar collagen I, tropocollagen and collagen I/heparin maintain important immunosuppressive properties of MSCs, which support their suitablility as carriers for MSC transplants in tissue engineering.
Journal Article
Protein kinase C phosphorylates the sponge aggregation receptor after its binding to the homologous aggregation factor.
H. C. Schröder,V. Amberger,K. Renneisen,Michael Bachmann,Branko Kurelec,G. Uhlenbruck,W. E. G. Müller +6 more
TL;DR: The results support the idea that phosphorylation of pp43.5 (= aggregation receptor) results in an inhibition of its function, i.e., the transduction of the growth factor (= aggregation factor) signal.
Journal ArticleDOI
And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling
Nicole Berndt,Claudia C. Bippes,Irene Michalk,Tabea Bartsch,Claudia Arndt,Edinson Puentes-Cala,Javier Andrés Soto,Javier Andrés Soto,Liliana R. Loureiro,Alexandra Kegler,Dominik Bachmann,Joanne K Gross,Tim Gross,Biji T. Kurien,R. Hal Scofield,A. Darise Farris,Judith A. James,Ralf Bergmann,Ralf Bergmann,Marc Schmitz,Anja Feldmann,Michael Bachmann,Michael Bachmann +22 more
TL;DR: In this paper, it was shown that ligands of toll-like receptors lead to a redox-dependent shuttling of La protein and showed that translocation of La proteins can be triggered in a ligand/receptor-dependent manner under physiological conditions.
Journal ArticleDOI
Directed migration of cells from the sponge Geodia cydonium.
Bärbel Diehl-Seifert,Verena Amberger,Monika Gramzow,Renato Batel,Michael Bachmann,Heinz C. Schröder,Werner E.G. Müller +6 more
TL;DR: The migration behavior of cells from the sponge Geodia cydonium was studied in vitro, applying the 'Tissue Culture Slide Chamber' technique, and evidence is presented that the chemotactic receptor on the cell surface is, in an hitherto unknown manner, coupled with the intracellularly present actin filaments.
Book ChapterDOI
SDS-PAGE to Immunoblot in One Hour
Biji T. Kurien,Biji T. Kurien,Biji T. Kurien,Debashish Danda,Michael Bachmann,R. Hal Scofield,R. Hal Scofield,R. Hal Scofield +7 more
TL;DR: An ultra-rapid method for electrophoresing proteins on sodium dodecyl sulfate-polyacrylamide gel Electrophoresis, transfer of proteins to nitrocellulose membranes, and immunoblotting is described here.