M
Michael Bachmann
Researcher at Helmholtz-Zentrum Dresden-Rossendorf
Publications - 402
Citations - 16252
Michael Bachmann is an academic researcher from Helmholtz-Zentrum Dresden-Rossendorf. The author has contributed to research in topics: Antigen & Chimeric antigen receptor. The author has an hindex of 63, co-authored 360 publications receiving 14388 citations. Previous affiliations of Michael Bachmann include ACADIA Pharmaceuticals Inc. & University of Southern California.
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Journal ArticleDOI
Expression of M-cadherin protein in myogenic cells during prenatal mouse development and differentiation of embryonic stem cells in culture.
Olaf Rose,Jürgen Rohwedel,Sigrid Reinhardt,Michael Bachmann,Matthias Cramer,Max Rotter,Anna M. Wobus,Anna Starzinski-Powitz +7 more
TL;DR: The results are in line with the idea that M‐cadherin might play a central role in myogenic morphogenesis, and coexpressed with the neuronal cell adhesion molecule N‐CAM which has been shown to mediate cell‐cell contact inMyogenic cells.
Journal ArticleDOI
Breast Cancer Cell Colonization of the Human Bone Marrow Adipose Tissue Niche
Zachary S. Templeton,Wen Rong Lie,Weiqi Wang,Yael Rosenberg-Hasson,Rajiv V. Alluri,John S. Tamaresis,Michael Bachmann,Kitty Lee,William J. Maloney,Christopher H. Contag,Bonnie L. King +10 more
TL;DR: Results show that breast cancer cells migrate to human bone tissue-conditioned medium in association with increasing levels of leptin and IL-1β, and colonize the bone marrow adipose tissue compartment of cultured fragments.
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Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology "UniCAR".
Anja Feldmann,Claudia Arndt,Ralf Bergmann,Simon Loff,Marc Cartellieri,Dominik Bachmann,Roberta Aliperta,Mirjam Hetzenecker,Florian Ludwig,Susann Albert,Pauline Ziller-Walter,Alexandra Kegler,Stefanie Koristka,Sebastian Gärtner,Marc Schmitz,Armin Ehninger,Gerhard Ehninger,Jens Pietzsch,Jens Pietzsch,Jörg Steinbach,Michael Bachmann +20 more
TL;DR: Preclinical data is presented summarizing the retargeting of UniCAR T cells to PCa cells using TMs directed to prostate stem cell- (PSCA) or/and prostate specific membrane antigen (PSMA) in the presence of the respective TM(s).
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Dendritic cell-based immunotherapy for prostate cancer.
Hanka Jähnisch,Susanne Füssel,Andrea Kiessling,Rebekka Wehner,Stefan Zastrow,Michael Bachmann,Ernst Peter Rieber,Manfred P. Wirth,Marc Schmitz +8 more
TL;DR: Dendritic cells (DCs) are professional antigen-presenting cells (APCs), which display an extraordinary capacity to induce, sustain, and regulate T-cell responses providing the opportunity of DC-based cancer vaccination strategies.
Journal ArticleDOI
Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay.
Mobin Karimi,Eric Lee,Michael Bachmann,Ana M. Salicioni,Edward M. Behrens,Taku Kambayashi,Cynthia L. Baldwin +6 more
TL;DR: It is concluded that the bioluminescence-based measurement of cytotoxicity offers a superior non-radioactive alternative to the chromium-release assay that is more robust and quicker to perform.