Michael Bachmann

TL;DR: It is shown that MSC inhibit the maturation of a subpopulation of human dendritic cells called slanDC, thereby impairing their ability to produce proinflammatory cytokines and to stimulate the proliferation of CD4+ and CD8+ T lymphocytes.

TL;DR: In this paper, the frequency and clinical relevance of plasmacytoid dendritic cells (pDCs) in primary tumor tissues from patients with colon cancer with different clinicopathological characteristics was investigated.

TL;DR: A novel modular platform technology in which T cell‐recruitment and tumor‐targeting domains of conventional bispecific antibodies are split to independent components, a universal effector module (EM) and replaceable monospecific/monovalent target modules (TMs) that form highly efficient T cell-retargeting complexes should allow for simultaneous retargeting of tumor antigens.

TL;DR: The SOX11-derived peptide LLRRYNVAKV is described which is capable of inducing human leukocyte antigen-A*0201-restricted and tumor-reactive CTLs and may serve as an attractive candidate for a T cell-based immunotherapy of glioma.

TL;DR: Experiments revealed that in non-dividing cells Nef is present both in the cytoplasm and the nucleus while in dividing cells the viral protein is present in the Cytoplasma and at the nuclear membrane.